Study on Photon Transport Problem Based on the Platform of Molecular Optical Simulation Environment

As an important molecular imaging modality, optical imaging has attracted increasing attention in the recent years. Since the physical experiment is usually complicated and expensive, research methods based on simulation platforms have obtained extensive attention. We developed a simulation platform named Molecular Optical Simulation Environment (MOSE) to simulate photon transport in both biological tissues and free space for optical imaging based on noncontact measurement. In this platform, Monte Carlo (MC) method and the hybrid radiosity-radiance theorem are used to simulate photon transport in biological tissues and free space, respectively, so both contact and noncontact measurement modes of optical imaging can be simulated properly. In addition, a parallelization strategy for MC method is employed to improve the computational efficiency. In this paper, we study the photon transport problems in both biological tissues and free space using MOSE. The results are compared with Tracepro, simplified spherical harmonics method (SPn), and physical measurement to verify the performance of our study method on both accuracy and efficiency

Photonic Quantum Simulators

Quantum simulators are controllable quantum systems that can be used to mimic other quantum systems. They have the potential to enable the tackling of problems that are intractable on conventional computers. The photonic quantum technology available today is reaching the stage where significant advantages arise for the simulation of interesting problems in quantum chemistry, quantum biology and solid-state physics. In addition, photonic quantum systems also offer the unique benefit of being mobile over free space and in waveguide structures, which opens new perspectives to the field by enabling the natural investigation of quantum transport phenomena. Here, we review recent progress in the field of photonic quantum simulation, which should break the ground towards the realization of versatile quantum simulators.Chemistry and Chemical Biolog

GEANT4 : a simulation toolkit

Abstract Geant4 is a toolkit for simulating the passage of particles through matter. It includes a complete range of functionality including tracking, geometry, physics models and hits. The physics processes offered cover a comprehensive range, including electromagnetic, hadronic and optical processes, a large set of long-lived particles, materials and elements, over a wide energy range starting, in some cases, from 250 eV and extending in others to the TeV energy range. It has been designed and constructed to expose the physics models utilised, to handle complex geometries, and to enable its easy adaptation for optimal use in different sets of applications. The toolkit is the result of a worldwide collaboration of physicists and software engineers. It has been created exploiting software engineering and object-oriented technology and implemented in the C++ programming language. It has been used in applications in particle physics, nuclear physics, accelerator design, space engineering and medical physics. PACS: 07.05.Tp; 13; 2

Micro-Channel Arrays by Two Photon Lithography for Cell Migration Studies

Metastasis is a dynamic process in which cancer cells begin to move. Understanding how these cells acquire increased motility is a stimulating and necessary goal. The goal of this thesis is to produce a microfluidic device that allows the study of chemotaxis of Neuroblastoma cells and the device was fabricated using an innovative two-photon polymerization (2PP) technology.openEmbargo temporaneo per motivi di segretezza e/o di proprietà dei risultati e/o informazioni sensibil

Qualitative Simulation of Photon Transport in Free Space Based on Monte Carlo Method and Its Parallel Implementation

During the past decade, Monte Carlo method has obtained wide applications in optical imaging to simulate photon transport process inside tissues. However, this method has not been effectively extended to the simulation of free-space photon transport at present. In this paper, a uniform framework for noncontact optical imaging is proposed based on Monte Carlo method, which consists of the simulation of photon transport both in tissues and in free space. Specifically, the simplification theory of lens system is utilized to model the camera lens equipped in the optical imaging system, and Monte Carlo method is employed to describe the energy transformation from the tissue surface to the CCD camera. Also, the focusing effect of camera lens is considered to establish the relationship of corresponding points between tissue surface and CCD camera. Furthermore, a parallel version of the framework is realized, making the simulation much more convenient and effective. The feasibility of the uniform framework and the effectiveness of the parallel version are demonstrated with a cylindrical phantom based on real experimental results