84 research outputs found

    Automatic Localization of Epileptic Spikes in EEGs of Children with Infantile Spasms

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    Infantile Spasms (ISS) characterized by electroencephalogram (EEG) recordings exhibiting hypsarrythmia (HYPS) are a severe form of epilepsy. Many clinicians have been trying to improve ISS outcomes; however, quantification of discharges from hypsarrythmic EEG readings remains challenging. This thesis describes the development of a novel method that assists clinicians to successfully localize the epileptic discharges associated with ISS in HYPS. The approach includes: construct the time-frequency domain (TFD) of the EEG recording using matching pursuit TFD (MP-TFD), decompose the TFD matrix into two submatrices using nonnegative matrix factorizations (NMF), and employ the decomposed vectors to locate the spikes. The proposed method was employed to an EEG dataset of five ISS individuals, and identification of spikes was compared with those which were identified by the epileptologists and those obtained using clinical software (Persyst). Performance evaluations showed results based on classification techniques: thresholdings, and support vector machine (SVM). Using the thresholdings, average true positive (TP) and false negative (FN) percentages of 86% and 14% were achieved, which represented a significant improvement over the use of Persyst, which only achieved average TP and FN percentages of 4% and 96%, respectively. Using SVM, the percentage of area under curve (AUC) of receiver operating characteristic (ROC) was significantly improved up to 98.56%. In summary, the proposed novel algorithm based on MP-TFD and NMF was able to successfully detect the epileptic discharges from the dataset. The development of the proposed automated method can potentially assist clinicians to successfully localize the epileptic discharges associated with ISS in HYPS. The quantitative assessment of spike detection, as well as other features of HYPS, is expected to allow a more accurate assessment of the relevance of EEG to clinical outcomes, which is significant in therapy management of ISS

    Towards the automated analysis of simple polyphonic music : a knowledge-based approach

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    PhDMusic understanding is a process closely related to the knowledge and experience of the listener. The amount of knowledge required is relative to the complexity of the task in hand. This dissertation is concerned with the problem of automatically decomposing musical signals into a score-like representation. It proposes that, as with humans, an automatic system requires knowledge about the signal and its expected behaviour to correctly analyse music. The proposed system uses the blackboard architecture to combine the use of knowledge with data provided by the bottom-up processing of the signal's information. Methods are proposed for the estimation of pitches, onset times and durations of notes in simple polyphonic music. A method for onset detection is presented. It provides an alternative to conventional energy-based algorithms by using phase information. Statistical analysis is used to create a detection function that evaluates the expected behaviour of the signal regarding onsets. Two methods for multi-pitch estimation are introduced. The first concentrates on the grouping of harmonic information in the frequency-domain. Its performance and limitations emphasise the case for the use of high-level knowledge. This knowledge, in the form of the individual waveforms of a single instrument, is used in the second proposed approach. The method is based on a time-domain linear additive model and it presents an alternative to common frequency-domain approaches. Results are presented and discussed for all methods, showing that, if reliably generated, the use of knowledge can significantly improve the quality of the analysis.Joint Information Systems Committee (JISC) in the UK National Science Foundation (N.S.F.) in the United states. Fundacion Gran Mariscal Ayacucho in Venezuela

    Time-Frequency Analysis of Systems with Changing Dynamic Properties

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    Time-frequency analysis methods transform a time series into a two-dimensional representation of frequency content with respect to time. The Fourier Transform identifies the frequency content of a signal (as a sum of weighted sinusoidal functions) but does not give useful information regarding changes in the character of the signal, as all temporal information is encoded in the phase of the transform. A time-frequency representation, by expressing frequency content at different sections of a record, allows for analysis of evolving signals. The time-frequency transformation most commonly encountered in seismology and civil engineering is a windowed Fourier Transform, or spectrogram; by comparing the frequency content of the first portion of a record with the last portion of the record, it is straightforward to identify the changes between the two segments. Extending this concept to a sliding window gives the spectrogram, where the Fourier transforms of successive portions of the record are assembled into a time-frequency representation of the signal. The spectrogram is subject to an inherent resolution limitation, in accordance with the uncertainty principle, that precludes a perfect representation of instantaneous frequency content. The wavelet transform was introduced to overcome some of the shortcomings of Fourier analysis, though wavelet methods are themselves unsuitable for many commonly encountered signals. The Wigner-Ville Distribution, and related refinements, represent a class of advanced time-frequency analysis tools that are distinguished from Fourier and wavelet methods by an increase in resolution in the time-frequency plane. I introduce several time-frequency representations and apply them to various synthetic signals as well as signals from instrumented buildings. vi For systems of interest to engineers, investigating the changing properties of a system is typically performed by analyzing vibration data from the system, rather than direct inspection of each component. Nonlinear elastic behavior in the forcedisplacement relationship can decrease the apparent natural frequencies of the system - these changes typically occur over fractions of a second in moderate to strong excitation and the system gradually recovers to pre-event levels. Structures can also suffer permanent damage (e.g., plastic deformation or fracture), permanently decreasing the observed natural frequencies as the system loses stiffness. Advanced time-frequency representations provide a set of exploratory tools for analyzing changing frequency content in a signal, which can then be correlated with damage patterns in a structure. Modern building instrumentation allows for an unprecedented investigation into the changing dynamic properties of structures: a framework for using time-frequency analysis methods for instantaneous system identification is discussed

    Diagnostic des machines dans le plan temps-frƩquence

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    Using short-time Fourier transform in machinery fault diagnosis -- Time-frequency distributions and their application to machinery fault detection -- Application of wavelet transform in machine fault detection -- Time-frequency algorithms and their applications

    A tutorial on onset detection in music signals

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