A Literature Survey of Cooperative Caching in Content Distribution Networks

Content distribution networks (CDNs) which serve to deliver web objects (e.g., documents, applications, music and video, etc.) have seen tremendous growth since its emergence. To minimize the retrieving delay experienced by a user with a request for a web object, caching strategies are often applied - contents are replicated at edges of the network which is closer to the user such that the network distance between the user and the object is reduced. In this literature survey, evolution of caching is studied. A recent research paper [15] in the field of large-scale caching for CDN was chosen to be the anchor paper which serves as a guide to the topic. Research studies after and relevant to the anchor paper are also analyzed to better evaluate the statements and results of the anchor paper and more importantly, to obtain an unbiased view of the large scale collaborate caching systems as a whole.Comment: 5 pages, 5 figure

A CQM-based approach to solving a combinatorial problem with applications in drug design

The use of D-Wave's Leap Hybrid solver is demonstrated here in solving a Knapsack optimization problem: finding meal combinations from a fixed menu that fit a diner's constraints. This is done by first formulating the optimization problem as a Constrained Quadratic Model (CQM) and then submitting it to a quantum annealer. We highlight here the steps needed, as well as the implemented code, and provide solutions from a Chicken and Waffle restaurant menu. Additionally, we discuss how this model may be generalized to find optimal drug molecules within a large search space with many complex, and often contradictory, structures and property constraints.Comment: 10 pages, 2 table

Discovering Valuable Items from Massive Data

Suppose there is a large collection of items, each with an associated cost and an inherent utility that is revealed only once we commit to selecting it. Given a budget on the cumulative cost of the selected items, how can we pick a subset of maximal value? This task generalizes several important problems such as multi-arm bandits, active search and the knapsack problem. We present an algorithm, GP-Select, which utilizes prior knowledge about similarity be- tween items, expressed as a kernel function. GP-Select uses Gaussian process prediction to balance exploration (estimating the unknown value of items) and exploitation (selecting items of high value). We extend GP-Select to be able to discover sets that simultaneously have high utility and are diverse. Our preference for diversity can be specified as an arbitrary monotone submodular function that quantifies the diminishing returns obtained when selecting similar items. Furthermore, we exploit the structure of the model updates to achieve an order of magnitude (up to 40X) speedup in our experiments without resorting to approximations. We provide strong guarantees on the performance of GP-Select and apply it to three real-world case studies of industrial relevance: (1) Refreshing a repository of prices in a Global Distribution System for the travel industry, (2) Identifying diverse, binding-affine peptides in a vaccine de- sign task and (3) Maximizing clicks in a web-scale recommender system by recommending items to users