14,093 research outputs found
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Ensuring Access to Safe and Nutritious Food for All Through the Transformation of Food Systems
One Small Step for Generative AI, One Giant Leap for AGI: A Complete Survey on ChatGPT in AIGC Era
OpenAI has recently released GPT-4 (a.k.a. ChatGPT plus), which is
demonstrated to be one small step for generative AI (GAI), but one giant leap
for artificial general intelligence (AGI). Since its official release in
November 2022, ChatGPT has quickly attracted numerous users with extensive
media coverage. Such unprecedented attention has also motivated numerous
researchers to investigate ChatGPT from various aspects. According to Google
scholar, there are more than 500 articles with ChatGPT in their titles or
mentioning it in their abstracts. Considering this, a review is urgently
needed, and our work fills this gap. Overall, this work is the first to survey
ChatGPT with a comprehensive review of its underlying technology, applications,
and challenges. Moreover, we present an outlook on how ChatGPT might evolve to
realize general-purpose AIGC (a.k.a. AI-generated content), which will be a
significant milestone for the development of AGI.Comment: A Survey on ChatGPT and GPT-4, 29 pages. Feedback is appreciated
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Quantifying and Explaining Machine Learning Uncertainty in Predictive Process Monitoring: An Operations Research Perspective
This paper introduces a comprehensive, multi-stage machine learning
methodology that effectively integrates information systems and artificial
intelligence to enhance decision-making processes within the domain of
operations research. The proposed framework adeptly addresses common
limitations of existing solutions, such as the neglect of data-driven
estimation for vital production parameters, exclusive generation of point
forecasts without considering model uncertainty, and lacking explanations
regarding the sources of such uncertainty. Our approach employs Quantile
Regression Forests for generating interval predictions, alongside both local
and global variants of SHapley Additive Explanations for the examined
predictive process monitoring problem. The practical applicability of the
proposed methodology is substantiated through a real-world production planning
case study, emphasizing the potential of prescriptive analytics in refining
decision-making procedures. This paper accentuates the imperative of addressing
these challenges to fully harness the extensive and rich data resources
accessible for well-informed decision-making
Preparation, modification, and clinical application of porous tantalum scaffolds
Porous tantalum (Ta) implants have been developed and clinically applied as high-quality implant biomaterials in the orthopedics field because of their excellent corrosion resistance, biocompatibility, osteointegration, and bone conductivity. Porous Ta allows fine bone ingrowth and new bone formation through the inner space because of its high porosity and interconnected pore structure. It contributes to rapid bone integration and long-term stability of osseointegrated implants. Porous Ta has excellent wetting properties and high surface energy, which facilitate the adhesion, proliferation, and mineralization of osteoblasts. Moreover, porous Ta is superior to classical metallic materials in avoiding the stress shielding effect, minimizing the loss of marginal bone, and improving primary stability because of its low elastic modulus and high friction coefficient. Accordingly, the excellent biological and mechanical properties of porous Ta are primarily responsible for its rising clinical translation trend. Over the past 2 decades, advanced fabrication strategies such as emerging manufacturing technologies, surface modification techniques, and patient-oriented designs have remarkably influenced the microstructural characteristic, bioactive performance, and clinical indications of porous Ta scaffolds. The present review offers an overview of the fabrication methods, modification techniques, and orthopedic applications of porous Ta implants
Self-Ordering Point Clouds
In this paper we address the task of finding representative subsets of points
in a 3D point cloud by means of a point-wise ordering. Only a few works have
tried to address this challenging vision problem, all with the help of hard to
obtain point and cloud labels. Different from these works, we introduce the
task of point-wise ordering in 3D point clouds through self-supervision, which
we call self-ordering. We further contribute the first end-to-end trainable
network that learns a point-wise ordering in a self-supervised fashion. It
utilizes a novel differentiable point scoring-sorting strategy and it
constructs an hierarchical contrastive scheme to obtain self-supervision
signals. We extensively ablate the method and show its scalability and superior
performance even compared to supervised ordering methods on multiple datasets
and tasks including zero-shot ordering of point clouds from unseen categories
Anuário científico da Escola Superior de Tecnologia da Saúde de Lisboa - 2021
É com grande prazer que apresentamos a mais recente edição (a 11.ª) do Anuário Científico da Escola Superior de Tecnologia da Saúde de Lisboa. Como instituição de ensino superior, temos o compromisso de promover e incentivar a pesquisa científica em todas as áreas do conhecimento que contemplam a nossa missão. Esta publicação tem como objetivo divulgar toda a produção científica desenvolvida pelos Professores, Investigadores, Estudantes e Pessoal não Docente da ESTeSL durante 2021. Este Anuário é, assim, o reflexo do trabalho árduo e dedicado da nossa comunidade, que se empenhou na produção de conteúdo científico de elevada qualidade e partilhada com a Sociedade na forma de livros, capítulos de livros, artigos publicados em revistas nacionais e internacionais, resumos de comunicações orais e pósteres, bem como resultado dos trabalhos de 1º e 2º ciclo. Com isto, o conteúdo desta publicação abrange uma ampla variedade de tópicos, desde temas mais fundamentais até estudos de aplicação prática em contextos específicos de Saúde, refletindo desta forma a pluralidade e diversidade de áreas que definem, e tornam única, a ESTeSL. Acreditamos que a investigação e pesquisa científica é um eixo fundamental para o desenvolvimento da sociedade e é por isso que incentivamos os nossos estudantes a envolverem-se em atividades de pesquisa e prática baseada na evidência desde o início dos seus estudos na ESTeSL. Esta publicação é um exemplo do sucesso desses esforços, sendo a maior de sempre, o que faz com que estejamos muito orgulhosos em partilhar os resultados e descobertas dos nossos investigadores com a comunidade científica e o público em geral. Esperamos que este Anuário inspire e motive outros estudantes, profissionais de saúde, professores e outros colaboradores a continuarem a explorar novas ideias e contribuir para o avanço da ciência e da tecnologia no corpo de conhecimento próprio das áreas que compõe a ESTeSL. Agradecemos a todos os envolvidos na produção deste anuário e desejamos uma leitura inspiradora e agradável.info:eu-repo/semantics/publishedVersio
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The Epidemiology and Genetic Architecture of Vitamin D Deficiency in African Children
Vitamin D deficiency is a common public health problem worldwide. However, little is known about the epidemiology of vitamin D deficiency in Africa. In this thesis, I aimed to determine: 1) the prevalence of and risk factors associated with vitamin D deficiency in studies conducted in Africa; 2) the prevalence and predictors of vitamin D deficiency in African children; 3) the association between vitamin D and iron deficiency in African children; and 4) genetic variants that influence vitamin D status in Africans.
In a systematic review and meta-analyses of previous vitamin D studies in Africa, the average prevalence of low vitamin D status was 18.5%, 34.2% and 59.5% using cut-offs of 25-hydroxyvitamin D (25(OH)D) levels of <30 nmol/L, <50 nmol/L and <75 nmol/L, respectively. Populations at risk of vitamin D deficiency included newborns, women, and people living in high latitudes or urban areas.
In an epidemiological study of young children living in Africa, the prevalence of low vitamin D status was 0.6%, 7.8% and 44.5% using cut-offs of 25(OH)D levels of GC2 variant of the group-specific component (GC) gene, which encodes vitamin D binding protein.
Vitamin D deficiency was also associated with 80% higher odds of iron deficiency in these children. Adjusted regression models revealed that vitamin D deficiency was associated with higher ferritin and hepcidin levels suggesting lower iron status, and reduced sTfR and transferrin levels and increased TSAT and serum iron levels suggesting improved iron status.
Genome-wide association study (GWAS) in Africans revealed genetic variants that influence vitamin D status in vitamin D metabolism genes: DHCR7/NADSYN1, CYP2R1 and GC. However, the majority of SNPs from previous European GWASs did not replicate in the current GWAS.
Findings from this thesis indicate that vitamin D deficiency is prevalent in many African populations and should be considered in public health strategies in Africa
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