2 research outputs found
Siamese Verification Framework for Autism Identification During Infancy Using Cortical Path Signature Features
Autism spectrum disorder (ASD) is a complex neurodevelopmental disability, which is lack of biologic diagnostic markers. Therefore, exploring the ASD Identification directly from brain imaging data has been an important topic. In this work, we propose the Siamese verification model to identify ASD using 6 and 12 months cortical features. Rather than directly classifying a testing subject is ASD or not, we determine whether it has the same or different label with the reference subject who has been successfully diagnosed. Then, based on the comparison to all the reference subjects, we can predict the label of the testing subject. The advantage of modeling the classification problem as a verification framework is that it can greatly enlarge the training data size and enable us to train a more accurate and reliable model in an end-to-end manner. In addition, to further improve the classification performance, we introduce the path signature (PS) features, which can capture the dynamic longitudinal information of the brain development for the ASD Identification. Experiments showed that our proposed method reaches the best result, i.e., 87% accuracy, 83% sensitivity and 90% specificity comparing to the state-of-the-art methods
Automatic Autism Spectrum Disorder Detection Using Artificial Intelligence Methods with MRI Neuroimaging: A Review
Autism spectrum disorder (ASD) is a brain condition characterized by diverse
signs and symptoms that appear in early childhood. ASD is also associated with
communication deficits and repetitive behavior in affected individuals. Various
ASD detection methods have been developed, including neuroimaging modalities
and psychological tests. Among these methods, magnetic resonance imaging (MRI)
imaging modalities are of paramount importance to physicians. Clinicians rely
on MRI modalities to diagnose ASD accurately. The MRI modalities are
non-invasive methods that include functional (fMRI) and structural (sMRI)
neuroimaging methods. However, the process of diagnosing ASD with fMRI and sMRI
for specialists is often laborious and time-consuming; therefore, several
computer-aided design systems (CADS) based on artificial intelligence (AI) have
been developed to assist the specialist physicians. Conventional machine
learning (ML) and deep learning (DL) are the most popular schemes of AI used
for diagnosing ASD. This study aims to review the automated detection of ASD
using AI. We review several CADS that have been developed using ML techniques
for the automated diagnosis of ASD using MRI modalities. There has been very
limited work on the use of DL techniques to develop automated diagnostic models
for ASD. A summary of the studies developed using DL is provided in the
appendix. Then, the challenges encountered during the automated diagnosis of
ASD using MRI and AI techniques are described in detail. Additionally, a
graphical comparison of studies using ML and DL to diagnose ASD automatically
is discussed. We conclude by suggesting future approaches to detecting ASDs
using AI techniques and MRI neuroimaging