71 research outputs found

    A Brief History of the Department of Geometry between Anniversaries 40 and 50

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    Fabrication feasibility study of a 20 watt per pound solar cell array Final report, 22 Feb. - Dec. 1965

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    Feasibility of large deployable solar photovoltaic cell array for electric propulsion syste

    Guided Medical Data Segmentation Using Structure-Aligned Planar Contours

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    Segmentation of 3D/4D biological images is a critical step for a wide range of applications such as treatment planning, quantitative analysis, virtual simulations, and rendering visualizations. Automatic segmentation methods are becoming more reliable, but many experts still rely on manual intervention which makes segmentation a time and resource intensive bottleneck. Marking boundary contours in 3D images can be difficult when images are often noisy or the delineation of biological tissue is unclear. Non-parallel contours can be more accurate and reduce the amount of marking necessary, but require extra effort to ensure boundary consistency and maintain spatial orientation. This dissertation focuses three problems that pertain to drawing non-parallel contour networks and generating a segmentation surface from those networks. First a guided structure-aligned segmentation system is detailed that utilizes prior structure knowledge from past segmentations of similar data. It employs a contouring protocol to aid in navigating the volume data and support using arbitrarily-oriented contouring planes placed to capture or follow the global structure shape. A user study is provided to test how well novices perform segmentation using this system. The following two problems then aim to improve different aspects of this system. A new deformation approach to reconstruction is discussed which deforms previous segmentation meshes to fit protocol drawn contours from new data instances in order to obtain accurate segmentations that have the correct topology and general shape and preserves fine details. The focus is on the problem of finding a correspondence between a mesh and a set of contours describing a similar shape. And finally, a new robust algorithm that resolves inconsistencies in contour networks is detailed. Inconsistent contours are faster and less demanding to draw, and they allow the segmenter to focus on drawing boundaries and not maintaining consistency. However, inconsistency is detrimental to most reconstruction algorithms, so the network must be fixed as a post process after drawing

    Ninteenth Aerospace Mechanisms Symposium

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    The proceedings of the 19th Aerospace Mechanisms Symposium are reported. Technological areas covered include space lubrication, bearings, aerodynamic devices, spacecraft/Shuttle latches, deployment, positioning, and pointing. Devices for spacecraft docking and manipulator and teleoperator mechanisms are also described

    Propfan Test Assessment (PTA)

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    The objectives of the Propfan Test Assessment (PTA) Program were to validate in flight the structural integrity of large-scale propfan blades and to measure noise characteristics of the propfan in both near and far fields. All program objectives were met or exceeded, on schedule and under budget. A Gulfstream Aerospace Corporation GII aircraft was modified to provide a testbed for the 2.74m (9 ft) diameter Hamilton Standard SR-7 propfan which was driven by a 4475 kw (600 shp) turboshaft engine mounted on the left-hand wing of the aircraft. Flight research tests were performed for 20 combinations of speed and altitude within a flight envelope that extended to Mach numbers of 0.85 and altitudes of 12,192m (40,000 ft). Propfan blade stress, near-field noise on aircraft surfaces, and cabin noise were recorded. Primary variables were propfan power and tip speed, and the nacelle tilt angle. Extensive low altitude far-field noise tests were made to measure flyover and sideline noise and the lateral attenuation of noise. In coopertion with the FAA, tests were also made of flyover noise for the aircraft at 6100m (20,000 ft) and 10,668m (35,000 ft). A final series of tests were flown to evaluate an advanced cabin wall noise treatment that was produced under a separate program by NASA-Langley Research Center

    FIBER-TEX 1992: The Sixth Conference on Advanced Engineering Fibers and Textile Structures for Composites

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    The FIBER-TEX 1992 proceedings contain the papers presented at the conference held on 27-29 Oct. 1992 at Drexel University. The conference was held to create a forum to encourage an interrelationship of the various disciplines involved in the fabrication of materials, the types of equipment, and the processes used in the production of advanced composite structures. Topics discussed were advanced engineering fibers, textile processes and structures, structural fabric production, mechanics and characteristics of woven composites, and the latest requirements for the use of textiles in the production of composite materials and structures as related to global activities focused on textile structural composites

    The 29th Aerospace Mechanisms Symposium

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    The proceedings of the 29th Aerospace Mechanisms Symposium, which was hosted by NASA Johnson Space Center and held at the South Shore Harbour Conference Facility on May 17-19, 1995, are reported. Technological areas covered include actuators, aerospace mechanism applications for ground support equipment, lubricants, pointing mechanisms joints, bearings, release devices, booms, robotic mechanisms, and other mechanisms for spacecraft

    Tracking and data relay satellite system configuration and tradeoff study. Volume 5: TDRS spacecraft design, part 1

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    A dual spin stabilized TDR spacecraft design is presented for low data rate (LDR) and medium data rate (MDR) user spacecraft telecommunication relay service. The relay satellite provides command and data return channels for unmanned users together with duplex voice and data communication channels for manned user spacecraft. TDRS/ground links are in the Ku band. Command links are provided at UHF for LDR users and S band for MDR users. Voice communication channels are provided at UHF/VHF for LDR users and at S band for MDR users. The spacecraft is designed for launch on the Delta 2914 with system deployment planned for 1978. This volume contains a description of the overall TDR spacecraft configuration, a detailed description of the spacecraft subsystems, a reliability analysis, and a product effectiveness plan

    Quantifying Membrane Topology at the Nanoscale

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    Changes in the shape of cellular membranes are linked with viral replication, Alzheimer\u27s, heart disease and an abundance of other maladies. Some membranous organelles, such as the endoplasmic reticulum and the Golgi, are only 50 nm in diameter. As such, membrane shape changes are conventionally studied with electron microscopy (EM), which preserves cellular ultrastructure and achieves a resolution of 2 nm or better. However, immunolabeling in EM is challenging, and often destroys the cell, making it difficult to study interactions between membranes and other proteins. Additionally, cells must be fixed in EM imaging, making it impossible to study mechanisms of disease. To address these problems, this thesis advances nanoscale imaging and analysis of membrane shape changes and their associated proteins using super-resolution single-molecule localization microscopy. This thesis is divided into three parts. In the first, a novel correlative orientation-independent differential interference contrast (OI-DIC) and single-molecule localization microscopy (SMLM) instrument is designed to address challenges with live-cell imaging of membrane nanostructure. SMLM super-resolution fluorescence techniques image with ~ 20 nm resolution, and are compatible with live-cell imaging. However, due to SMLM\u27s slow imaging speeds, most cell movement is under-sampled. OI-DIC images fast, is gentle enough to be used with living cells and can image cellular structure without labelling, but is diffraction-limited. Combining SMLM with OI-DIC allows for imaging of cellular context that can supplement sparse super-resolution data in real time. The second part of the thesis describes an open-source software package for visualizing and analyzing SMLM data. SMLM imaging yields localization point clouds, which requires non-standard visualization and analysis techniques. Existing techniques are described, and necessary new ones are implemented. These tools are designed to interpret data collected from the OI-DIC/SMLM microscope, as well as from other optical setups. Finally, a tool for extracting membrane structure from SMLM point clouds is described. SMLM data is often noisy, containing multiple localizations per fluorophore and many non-specific localizations. SMLM\u27s resolution reveals labelling discontinuities, which exacerbate sparsity of localizations. It is non-trivial to reconstruct the continuous shape of a membrane from a discrete set of points, and even more difficult in the presence of the noise profile characteristic of most SMLM point clouds. To address this, a surface reconstruction algorithm for extracting continuous surfaces from SMLM data is implemented. This method employs biophysical curvature constraints to improve the accuracy of the surface

    Bibliography of Lewis Research Center technical publications announced in 1980

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    This compilation of abstracts describes and indexes over 780 research reports, journal articles, conference presentations, patents and patent applications, and theses resulting from the scientific and engineering work performed and managed by the Lewis Research Center in 1980. All the publications were announced in Scientific and Technical Aerospace Reports and/or International Aerospace Abstracts
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