Population, sexual and reproductive health, rights and sustainable development: forging a common agenda.

This article suggests that sexual and reproductive health and rights activists seeking to influence the post-2015 international development paradigm must work with sustainable development advocates concerned with a range of issues, including climate change, environmental issues, and food and water security, and that a way of building bridges with these communities is to demonstrate how sexual and reproductive health and rights are relevant for these issues. An understanding of population dynamics, including urbanization and migration, as well as population growth, can help to clarify these links. This article therefore suggests that whether or not sexual and reproductive health and rights activists can overcome resistance to discussing "population", become more knowledgeable about other sustainable development issues, and work with others in those fields to advance the global sustainable development agenda are crucial questions for the coming months. The article also contends that it is possible to care about population dynamics (including ageing and problems faced by countries with a high proportion of young people) and care about human rights at the same time. It expresses concern that, if sexual and reproductive health and rights advocates do not participate in the population dynamics discourse, the field will be left free for those for whom respecting and protecting rights may be less of a priority

Functional Profiling of Transcription Factor Genes in Neurospora crassa.

Regulation of gene expression by DNA-binding transcription factors is essential for proper control of growth and development in all organisms. In this study, we annotate and characterize growth and developmental phenotypes for transcription factor genes in the model filamentous fungus Neurospora crassa We identified 312 transcription factor genes, corresponding to 3.2% of the protein coding genes in the genome. The largest class was the fungal-specific Zn2Cys6 (C6) binuclear cluster, with 135 members, followed by the highly conserved C2H2 zinc finger group, with 61 genes. Viable knockout mutants were produced for 273 genes, and complete growth and developmental phenotypic data are available for 242 strains, with 64% possessing at least one defect. The most prominent defect observed was in growth of basal hyphae (43% of mutants analyzed), followed by asexual sporulation (38%), and the various stages of sexual development (19%). Two growth or developmental defects were observed for 21% of the mutants, while 8% were defective in all three major phenotypes tested. Analysis of available mRNA expression data for a time course of sexual development revealed mutants with sexual phenotypes that correlate with transcription factor transcript abundance in wild type. Inspection of this data also implicated cryptic roles in sexual development for several cotranscribed transcription factor genes that do not produce a phenotype when mutated

THE SEXUAL ORIENTATION OF CELIE IN ALICE WALKER’S THE COLOR PURPLE

The objectives of this research are to reveal the factors that cause Celie to become a lesbian and to describe Celie‟s homosexual identity development. The researcher used sexual orientation, lesbianism and other related theories to answer the formulated research questions. The method used in this research is qualitative content analysis. The subject of this research is a novel entitled The Color Purple by Walker. The data are some phrases, clauses, and sentences related to the factors that cause Celie to become a lesbian and process of Celie‟s homosexual identity development. The key instrument of this research is the researcher herself employing sexual orientation theory by Giddens and lesbianism theory by Rich as explained in the conceptual framework. Sexual orientation and lesbianism are used as the grand theories for the analysis. The indicators made are based on the employed theories to gain the research data. To gain the trustworthiness, the researcher used data triangulation technique by crosschecking the data with her consultants and other researchers. The findings of the research show two important points. First, the factors that cause Celie to become a lesbian are psychological and social/environmental factors. Second, Celie‟s homosexual identity development process covers four stages: sensitization or emergence, identity confusion, identity assumptiopn and first relationship

Assessment of sexual difficulties associated with multi-modal treatment for cervical or endometrial cancer: A systematic review of measurement instruments

Background: Practitioners and researchers require an outcome measure that accurately identifies the range of common treatment-induced changes in sexual function and well-being experienced by women after cervical or endometrial cancer. This systematic review critically appraised the measurement properties and clinical utility of instruments validated for the measurement of female sexual dysfunction (FSD) in this clinical population. Methods: A bibliographic database search for questionnaire development or validation papers was completed and methodological quality and measurement properties of selected studies rated using the Consensus-based Standards for the selection of health Measurement Instrument (COSMIN) checklist. Results: 738 articles were screened, 13 articles retrieved for full text assessment and 7 studies excluded, resulting in evaluation of 6 papers; 2 QoL and 4 female sexual morbidity measures. Five of the six instruments omitted one or more dimension of female sexual function and only one instrument explicitly measured distress associated with sexual changes as per DSM V (APA 2013) diagnostic criteria. None of the papers reported measurement error, responsiveness data was available for only two instruments, three papers failed to report on criterion validity, and test-retest reliability reporting was inconsistent. Heterosexual penile-vaginal intercourse remains the dominant sexual activity focus for sexual morbidity PROMS terminology and instruments lack explicit reference to solo or non-coital sexual expression or validation in a non-heterosexual sample. Four out of six instruments included mediating treatment or illness items such as vaginal changes, menopause or altered body image. Conclusions: Findings suggest that the Female Sexual Function Index (FSFI) remains the most robust sexual morbidity outcome measure, for research or clinical use, in sexually active women treated for cervical or endometrial cancer

The "backdoor pathway" of androgen synthesis in human male sexual development.

Mammalian sex determination (male versus female) is largely controlled by genes, whereas sex differentiation (development of reproductive structures) is largely controlled by hormones. Work in the 20th century indicated that female external anatomy was a "default" pathway of development not requiring steroids, whereas male genital development required testicular testosterone plus dihydrotestosterone (DHT) made in genital skin according to a "classic" pathway. Recent work added the description of an alternative "backdoor" pathway of androgen synthesis discovered in marsupials. Unique "backdoor steroids" are found in human hyperandrogenic disorders, and genetic disruption of the pathway causes disordered male sexual development, suggesting it plays an essential role. O'Shaughnessy and colleagues now show that the principal human backdoor androgen is androsterone and provide strong evidence that it derives from placental progesterone that is metabolized to androsterone in nontesticular tissues. These studies are essential to understanding human sexual development and its disorders

Sex, AIDS, Migration, and Prostitution: Human Trafficking in the Caribbean

Study of sexual tourism in Saint Martin/Sint Maarten, where prostitution is a widespread reality. Author argues that on this island where rapid economic development is based on the tourist industry and on offshore financial services, sexual relationships are determined by geopolitical and financial (neoliberal) interests that go beyond sexuality per se. She focuses on the precarious situation of the foreign prostitutes who have no working papers

Sexual selection in the Swallow Hirundo rustica - A review

Darwinian theory of sexual selection and its development up to the present state of knowledge are sketched. The most important results of empirical studies on sexual selection in the Swallow Hirundo rustica are reviewed. The Swallow is a socially monogamous, slightly sexually dimorphic avian species. Long tail streamers are considered as sexual ornaments of males. Female preference for long and symmetric male tails has been inferred on both observational and experimental grounds. Experimental elongation of the tail causes short-term benefits and long-term costs in male reproductive performance. Behavioural consequences of sexual selection acting in the Swallow are discussed. An aerodynamic role of male tail streamers is also considered.Zadanie pt. „Digitalizacja i udostępnienie w Cyfrowym Repozytorium Uniwersytetu Łódzkiego kolekcji czasopism naukowych wydawanych przez Uniwersytet Łódzki” nr 885/P-DUN/2014 dofinansowane zostało ze środków MNiSW w ramach działalności upowszechniającej naukę

Turning on and turning off: A focus group study of the factors that affect women's sexual arousal

This is a post print version of the article. The official published version can be accessed from the link below.The aim of this study was to inform the development of a questionnaire to assess a woman's tendency to respond with sexual excitation/inhibition in different situations. Nine focus groups, involving 80 women (M age = 34.3 years; range, 18-84), were conducted. Women described a wide range of physical (genital and nongenital), cognitive/emotional, and behavioral cues to arousal. The relationship between sexual interest (desire) and sexual arousal was complex; sexual interest was reported as sometimes preceding arousal, but at other times following it. Many women did not clearly differentiate between arousal and interest. Qualitative data on the factors that women perceived as enhancers and inhibitors of sexual arousal are presented, with a focus on the following themes: feelings about one's body; concern about reputation; unwanted pregnancy/ contraception; feeling desired versus feeling used by a partner; feeling accepted by a partner; style of approach/initiation; and negative mood. The findings can help inform conceptualizations of sexual arousal in women.This research was funded (in part) by a grant from the Lilly Centre for Women‟s Health

Rape Talk: Student Awareness and Perceptions of Campus Sexual Assault and Resources

This project evaluates student perceptions of campus sexual assault and related resources at Marquette University of Milwaukee, Wisconsin. As campus sexual assault and an unsafe rape culture are still persistent, research is needed to bring about awareness and spark an open discourse of this issue. The original data of this project consists of the researcher’s autoethnography, observations of Marquette’s online sexual violence resources, student interviews, and an online student survey. After analyzing this data, the most important finding was that students do not share the same perceptions and knowledge of this issue, despite receiving the same resources. Also, the relationship between Marquette students and staff and other non-student people is distant and in need of development. Lastly, students want to see more change on campus concerning this issue. However, the overarching theme of their desires for change is a wish for more transparency on campus.https://epublications.marquette.edu/english_3210ur/1028/thumbnail.jp