Multi-body Non-rigid Structure-from-Motion

Conventional structure-from-motion (SFM) research is primarily concerned with the 3D reconstruction of a single, rigidly moving object seen by a static camera, or a static and rigid scene observed by a moving camera --in both cases there are only one relative rigid motion involved. Recent progress have extended SFM to the areas of {multi-body SFM} (where there are {multiple rigid} relative motions in the scene), as well as {non-rigid SFM} (where there is a single non-rigid, deformable object or scene). Along this line of thinking, there is apparently a missing gap of "multi-body non-rigid SFM", in which the task would be to jointly reconstruct and segment multiple 3D structures of the multiple, non-rigid objects or deformable scenes from images. Such a multi-body non-rigid scenario is common in reality (e.g. two persons shaking hands, multi-person social event), and how to solve it represents a natural {next-step} in SFM research. By leveraging recent results of subspace clustering, this paper proposes, for the first time, an effective framework for multi-body NRSFM, which simultaneously reconstructs and segments each 3D trajectory into their respective low-dimensional subspace. Under our formulation, 3D trajectories for each non-rigid structure can be well approximated with a sparse affine combination of other 3D trajectories from the same structure (self-expressiveness). We solve the resultant optimization with the alternating direction method of multipliers (ADMM). We demonstrate the efficacy of the proposed framework through extensive experiments on both synthetic and real data sequences. Our method clearly outperforms other alternative methods, such as first clustering the 2D feature tracks to groups and then doing non-rigid reconstruction in each group or first conducting 3D reconstruction by using single subspace assumption and then clustering the 3D trajectories into groups.Comment: 21 pages, 16 figure

Stratified decision forests for accurate anatomical landmark localization in cardiac images

Accurate localization of anatomical landmarks is an important step in medical imaging, as it provides useful prior information for subsequent image analysis and acquisition methods. It is particularly useful for initialization of automatic image analysis tools (e.g. segmentation and registration) and detection of scan planes for automated image acquisition. Landmark localization has been commonly performed using learning based approaches, such as classifier and/or regressor models. However, trained models may not generalize well in heterogeneous datasets when the images contain large differences due to size, pose and shape variations of organs. To learn more data-adaptive and patient specific models, we propose a novel stratification based training model, and demonstrate its use in a decision forest. The proposed approach does not require any additional training information compared to the standard model training procedure and can be easily integrated into any decision tree framework. The proposed method is evaluated on 1080 3D highresolution and 90 multi-stack 2D cardiac cine MR images. The experiments show that the proposed method achieves state-of-theart landmark localization accuracy and outperforms standard regression and classification based approaches. Additionally, the proposed method is used in a multi-atlas segmentation to create a fully automatic segmentation pipeline, and the results show that it achieves state-of-the-art segmentation accuracy

Deep Learning in Cardiology

The medical field is creating large amount of data that physicians are unable to decipher and use efficiently. Moreover, rule-based expert systems are inefficient in solving complicated medical tasks or for creating insights using big data. Deep learning has emerged as a more accurate and effective technology in a wide range of medical problems such as diagnosis, prediction and intervention. Deep learning is a representation learning method that consists of layers that transform the data non-linearly, thus, revealing hierarchical relationships and structures. In this review we survey deep learning application papers that use structured data, signal and imaging modalities from cardiology. We discuss the advantages and limitations of applying deep learning in cardiology that also apply in medicine in general, while proposing certain directions as the most viable for clinical use.Comment: 27 pages, 2 figures, 10 table

Deep learning cardiac motion analysis for human survival prediction

Motion analysis is used in computer vision to understand the behaviour of moving objects in sequences of images. Optimising the interpretation of dynamic biological systems requires accurate and precise motion tracking as well as efficient representations of high-dimensional motion trajectories so that these can be used for prediction tasks. Here we use image sequences of the heart, acquired using cardiac magnetic resonance imaging, to create time-resolved three-dimensional segmentations using a fully convolutional network trained on anatomical shape priors. This dense motion model formed the input to a supervised denoising autoencoder (4Dsurvival), which is a hybrid network consisting of an autoencoder that learns a task-specific latent code representation trained on observed outcome data, yielding a latent representation optimised for survival prediction. To handle right-censored survival outcomes, our network used a Cox partial likelihood loss function. In a study of 302 patients the predictive accuracy (quantified by Harrell's C-index) was significantly higher (p < .0001) for our model C=0.73 (95$\%$ CI: 0.68 - 0.78) than the human benchmark of C=0.59 (95$\%$ CI: 0.53 - 0.65). This work demonstrates how a complex computer vision task using high-dimensional medical image data can efficiently predict human survival