A statement by Scientists for Future concerning the protests for more climate protection

In March 2019, German-speaking scientists and scholars calling themselves Scientists for Future, published a statement in support of the youth protesters in Germany, Austria, and Switzerland (Fridays for Future, Klimastreik/Climate Strike), verifying the scientific evidence that the youth protestors refer to. In this article, they provide the full text of the statement, including the list of supporting facts (in both English and German) as well as an analysis of the results and impacts of the statement. Furthermore, they reflect on the challenges for scientists and scholars who feel a dual responsibility: on the one hand, to remain independent and politically neutral, and, on the other hand, to inform and warn societies of the dangers that lie ahead

Optimizing Guideline-Recommended Antibiotic Doses for Pediatric Infective Endocarditis

The American Heart Association recently published an updated scientific statement on the management of infective endocarditis in childhood. The recommendations included for vancomycin, aminoglycoside, and β-lactam dosing and monitoring are based primarily on expert opinion and do not consider available evidence for dose optimization based on pharmacokinetic and pharmacodynamic principles in pediatric patients. This is concerning because even when clinically necessary, some practitioners may be hesitant to deviate from guideline-recommended doses. In this perspective, we highlight potential areas for improvement in the statement-recommended doses and summarize evidence supporting antibiotic dosing optimization. The addition of a pediatric clinical pharmacist with expertise in antibiotic dosing to the panel would be beneficial for future updates

Apriorist self-interest: How it embraces altruism and is not vacuous

This essay is part of an attempt to reconcile two extreme views in economics: the (neglected) subjective, apriorist approach and the (standard) objective, scientific (i.e., falsifiable) approach. The Austrian subjective view of value, building on Carl Menger’s theory of value, was developed into a theory of economics as being entirely an a priori theory of action. This probably finds its most extreme statement in Ludwig von Mises’ Human Action (1949). In contrast, the standard economic view has developed into making falsifiable predictions about economic phenomena whereby the truth of the assumptions, especially about economic agents, is relatively unimportant: predictive fecundity is all. This finds an extreme statement in Milton Friedman’s introductory essay in his Essays in Positive Economics (1953). However, many economists fall somewhere between the two extremes, such as McKenzie and Tullock (1978)

Lakatos on justificationism

According to the scientific "justificationist" method, knowledge consisted of proven sentences. Classical intellectuals (or "rationalists," in the narrow sense of the term) have accepted extremely varied - and powerful "proofs", through revelation, intellectual intuition, experience. These, with the help of logic, have allowed them to prove any kind of scientific statement. Classical empiricists accepted as axioms only a relatively small set of "factual propositions" that expressed "hard facts". The value of their truth has been established by experience and has been the empirical basis of science. DOI: 10.13140/RG.2.2.28722.2528

Falsification and refutation

A scientific theory, according to Popper, can be legitimately saved from falsification by introducing an auxiliary hypothesis to generate new, falsifiable predictions. Also, if there are suspicions of bias or error, the researchers might introduce an auxiliary falsifiable hypothesis that would allow testing. But this technique can not solve the problem in general, because any auxiliary hypothesis can be challenged in the same way, ad infinitum. To solve this regression, Popper introduces the idea of ​​a basic statement, an empirical statement that can be used both to determine whether a given theory is falsifiable and, if necessary, to corroborate falsification assumptions. DOI: 10.13140/RG.2.2.22162.0992

Correct statement of a scattering problem for quantum charged scalar particles on the Reissner-Nordstr\"{o}m black holes

We study a correct statement of the scattering problem arising for quantum charged scalar particles on the Reissner-Nordstr\"{o}m black holes when taking into account the own electric field of black hole. The elements of the corresponding S-matrix are explored in the form convenient to physical applications and for applying numerical methods. Some further possible issues are outlined.Comment: 12 pages, LaTeX with using the ijmpd1.sty file from the package of World Scientific Publishing Co., to appear in Int. J. Mod. Phys. D7 (1998

Do Alternative Therapies Have a Role in Autism?

Interventions considered to be branches of Complementary & Alternative Medicine (CAM) for autism are on the rise. Many new treatments have emerged & traditional beliefs of Ayurveda, Yoga, Behavioral therapy, Speech therapy and Homoeopathy have gained popularity and advocacy among parents. It is imperative that data supporting new treatments should be scrutinized for scientific study design, clinical safety, and scientific validity, before embarking on them as modes of therapy. Practitioners take care in explaining the rationale behind the various approaches that they practice, it is important to indicate possible limitations too during the initial clinical examination and interactive session. Clinicians must remember that parents may have different beliefs regarding the effectiveness of treatment since their information is derived more from the ‘hear-say’ route when they compare benefits/effects of CAM therapies on other children and often underestimate differential tolerance for treatment risks. It is thus significant that practitioners do not assume a "don't ask, don't tell" posture. The scientific validation and support for many interventions is incomplete and very different from the recommendations of the American Academy of Pediatrics Policy Statement. In this article, we discuss the various modes of CAM and their utilities and limitations in relation to autism

Inflammatory Airway Disease of Horses - Revised Consensus Statement

The purpose of this manuscript is to revise and update the previous consensus statement on inflammatory airway disease (IAD) in horses. Since 2007, a large number of scientific articles have been published on the topic and these new findings have led to a significant evolution of our understanding of IAD

2015 ACVIM Small Animal Consensus Statement on Seizure Management in Dogs

This report represents a scientific and working clinical consensus statement on seizure management in dogs based on current literature and clinical expertise. The goal was to establish guidelines for a predetermined, concise, and logical sequential approach to chronic seizure management starting with seizure identification and diagnosis (not included in this report), reviewing decision‐making, treatment strategies, focusing on issues related to chronic antiepileptic drug treatment response and monitoring, and guidelines to enhance patient response and quality of life. Ultimately, we hope to provide a foundation for ongoing and future clinical epilepsy research in veterinary medicine