MOLNs: A cloud platform for interactive, reproducible and scalable spatial stochastic computational experiments in systems biology using PyURDME

Computational experiments using spatial stochastic simulations have led to important new biological insights, but they require specialized tools, a complex software stack, as well as large and scalable compute and data analysis resources due to the large computational cost associated with Monte Carlo computational workflows. The complexity of setting up and managing a large-scale distributed computation environment to support productive and reproducible modeling can be prohibitive for practitioners in systems biology. This results in a barrier to the adoption of spatial stochastic simulation tools, effectively limiting the type of biological questions addressed by quantitative modeling. In this paper, we present PyURDME, a new, user-friendly spatial modeling and simulation package, and MOLNs, a cloud computing appliance for distributed simulation of stochastic reaction-diffusion models. MOLNs is based on IPython and provides an interactive programming platform for development of sharable and reproducible distributed parallel computational experiments

Ultra-reliable Low-latency, Energy-efficient and Computing-centric Software Data Plane for Network Softwarization

Network softwarization plays a significantly important role in the development and deployment of the latest communication system for 5G and beyond. A more flexible and intelligent network architecture can be enabled to provide support for agile network management, rapid launch of innovative network services with much reduction in Capital Expense (CAPEX) and Operating Expense (OPEX). Despite these benefits, 5G system also raises unprecedented challenges as emerging machine-to-machine and human-to-machine communication use cases require Ultra-Reliable Low Latency Communication (URLLC). According to empirical measurements performed by the author of this dissertation on a practical testbed, State of the Art (STOA) technologies and systems are not able to achieve the one millisecond end-to-end latency requirement of the 5G standard on Commercial Off-The-Shelf (COTS) servers. This dissertation performs a comprehensive introduction to three innovative approaches that can be used to improve different aspects of the current software-driven network data plane. All three approaches are carefully designed, professionally implemented and rigorously evaluated. According to the measurement results, these novel approaches put forward the research in the design and implementation of ultra-reliable low-latency, energy-efficient and computing-first software data plane for 5G communication system and beyond

Can open-source projects (re-) shape the SDN/NFV-driven telecommunication market?

Telecom network operators face rapidly changing business needs. Due to their dependence on long product cycles they lack the ability to quickly respond to changing user demands. To spur innovation and stay competitive, network operators are investigating technological solutions with a proven track record in other application domains such as open source software projects. Open source software enables parties to learn, use, or contribute to technology from which they were previously excluded. OSS has reshaped many application areas including the landscape of operating systems and consumer software. The paradigmshift in telecommunication systems towards Software-Defined Networking introduces possibilities to benefit from open source projects. Implementing the control part of networks in software enables speedier adaption and innovation, and less dependencies on legacy protocols or algorithms hard-coded in the control part of network devices. The recently proposed concept of Network Function Virtualization pushes the softwarization of telecommunication functionalities even further down to the data plane. Within the NFV paradigm, functionality which was previously reserved for dedicated hardware implementations can now be implemented in software and deployed on generic Commercial Off-The Shelf (COTS) hardware. This paper provides an overview of existing open source initiatives for SDN/NFV-based network architectures, involving infrastructure to orchestration-related functionality. It situates them in a business process context and identifies the pros and cons for the market in general, as well as for individual actors

A collaborative citizen science platform for real-time volunteer computing and games

Volunteer computing (VC) or distributed computing projects are common in the citizen cyberscience (CCS) community and present extensive opportunities for scientists to make use of computing power donated by volunteers to undertake large-scale scientific computing tasks. Volunteer computing is generally a non-interactive process for those contributing computing resources to a project whereas volunteer thinking (VT) or distributed thinking, which allows volunteers to participate interactively in citizen cyberscience projects to solve human computation tasks. In this paper we describe the integration of three tools, the Virtual Atom Smasher (VAS) game developed by CERN, LiveQ, a job distribution middleware, and CitizenGrid, an online platform for hosting and providing computation to CCS projects. This integration demonstrates the combining of volunteer computing and volunteer thinking to help address the scientific and educational goals of games like VAS. The paper introduces the three tools and provides details of the integration process along with further potential usage scenarios for the resulting platform.Comment: 12 pages, 13 figure

myTrustedCloud: Trusted cloud infrastructure for security-critical computation and data managment

Copyright @ 2012 IEEECloud Computing provides an optimal infrastructure to utilise and share both computational and data resources whilst allowing a pay-per-use model, useful to cost-effectively manage hardware investment or to maximise its utilisation. Cloud Computing also offers transitory access to scalable amounts of computational resources, something that is particularly important due to the time and financial constraints of many user communities. The growing number of communities that are adopting large public cloud resources such as Amazon Web Services [1] or Microsoft Azure [2] proves the success and hence usefulness of the Cloud Computing paradigm. Nonetheless, the typical use cases for public clouds involve non-business critical applications, particularly where issues around security of utilization of applications or deposited data within shared public services are binding requisites. In this paper, a use case is presented illustrating how the integration of Trusted Computing technologies into an available cloud infrastructure - Eucalyptus - allows the security-critical energy industry to exploit the flexibility and potential economical benefits of the Cloud Computing paradigm for their business-critical applications

Data-Driven Methods for Data Center Operations Support

During the last decade, cloud technologies have been evolving at an impressive pace, such that we are now living in a cloud-native era where developers can leverage on an unprecedented landscape of (possibly managed) services for orchestration, compute, storage, load-balancing, monitoring, etc. The possibility to have on-demand access to a diverse set of configurable virtualized resources allows for building more elastic, flexible and highly-resilient distributed applications. Behind the scenes, cloud providers sustain the heavy burden of maintaining the underlying infrastructures, consisting in large-scale distributed systems, partitioned and replicated among many geographically dislocated data centers to guarantee scalability, robustness to failures, high availability and low latency. The larger the scale, the more cloud providers have to deal with complex interactions among the various components, such that monitoring, diagnosing and troubleshooting issues become incredibly daunting tasks. To keep up with these challenges, development and operations practices have undergone significant transformations, especially in terms of improving the automations that make releasing new software, and responding to unforeseen issues, faster and sustainable at scale. The resulting paradigm is nowadays referred to as DevOps. However, while such automations can be very sophisticated, traditional DevOps practices fundamentally rely on reactive mechanisms, that typically require careful manual tuning and supervision from human experts. To minimize the risk of outages—and the related costs—it is crucial to provide DevOps teams with suitable tools that can enable a proactive approach to data center operations. This work presents a comprehensive data-driven framework to address the most relevant problems that can be experienced in large-scale distributed cloud infrastructures. These environments are indeed characterized by a very large availability of diverse data, collected at each level of the stack, such as: time-series (e.g., physical host measurements, virtual machine or container metrics, networking components logs, application KPIs); graphs (e.g., network topologies, fault graphs reporting dependencies among hardware and software components, performance issues propagation networks); and text (e.g., source code, system logs, version control system history, code review feedbacks). Such data are also typically updated with relatively high frequency, and subject to distribution drifts caused by continuous configuration changes to the underlying infrastructure. In such a highly dynamic scenario, traditional model-driven approaches alone may be inadequate at capturing the complexity of the interactions among system components. DevOps teams would certainly benefit from having robust data-driven methods to support their decisions based on historical information. For instance, effective anomaly detection capabilities may also help in conducting more precise and efficient root-cause analysis. Also, leveraging on accurate forecasting and intelligent control strategies would improve resource management. Given their ability to deal with high-dimensional, complex data, Deep Learning-based methods are the most straightforward option for the realization of the aforementioned support tools. On the other hand, because of their complexity, this kind of models often requires huge processing power, and suitable hardware, to be operated effectively at scale. These aspects must be carefully addressed when applying such methods in the context of data center operations. Automated operations approaches must be dependable and cost-efficient, not to degrade the services they are built to improve. i