Major Outcomes in Atrial Fibrillation Patients with One Risk Factor: Impact of Time in Therapeutic Range

BACKGROUND: The benefits and harms of oral anticoagulation (OAC) therapy in patients with only one stroke risk factor (i.e. CHA2DS2-VASc= 1 in males, or 2 in females) has been subject of debate. METHODS: We analysed all patients with only one stroke risk factor from the merged datasets of SPORTIF III and V trials. Anticoagulation control was defined according to time in therapeutic range (TTR). RESULTS: Of the original trial cohort, 1,097 patients had only one stroke risk factor. Stroke/systemic thromboembolic event had an incidence of 0.9 per 100 patient-years, with an incidence of 1.6 per 100 patient-years for all-cause death and 2.3%/patient-years for the composite outcome of stroke/systemic thromboembolic event/all-cause death. There were no significant differences in the risk for stroke/systemic thromboembolic event between sexes, nor between the different stroke risk factors amongst these atrial fibrillation patients with only one stroke risk factor. Cox regression analysis in patients treated with warfarin only found TTR to be inversely associated with stroke/systemic thromboembolic event (p=0.034) and all-cause death (p=0.015). Chronic heart failure was significantly associated with the outcome of all-cause death (p=0.0019) and the composite outcome of stroke/systemic thromboembolic event/all-cause death (p=0.021). There was a significant inverse linear association between TTR and the cumulative risk for both stroke/systemic thromboembolic event and all-cause death (both p<0.001). CONCLUSIONS: In atrial fibrillation patients with only one additional stroke risk factor (i.e. CHA2DS2-VASc= 1 in males or 2 in females), rates of major adverse events (stroke/systemic thromboembolic event, mortality) were high, despite anticoagulation. TTR in warfarin-treated patients was inversely associated with the occurrence of both stroke/systemic thromboembolic event and all-cause death

Country reports Clean Clothes Campaign – November 2003 – February 2004

A compilation of country reports on the activities of the various European Clean Clothes Campaigns from November 2003 to February 2004

280 Birds with One Stone: Inducing Multilingual Taxonomies from Wikipedia using Character-level Classification

We propose a simple, yet effective, approach towards inducing multilingual taxonomies from Wikipedia. Given an English taxonomy, our approach leverages the interlanguage links of Wikipedia followed by character-level classifiers to induce high-precision, high-coverage taxonomies in other languages. Through experiments, we demonstrate that our approach significantly outperforms the state-of-the-art, heuristics-heavy approaches for six languages. As a consequence of our work, we release presumably the largest and the most accurate multilingual taxonomic resource spanning over 280 languages

METAPHORS AS A DYNAMIC ARTEFACT OF SOCIAL VALUES EXPRESSED IN LETTERS TO EDITORS

Metaphor discussed in this paper is an expression formulated from metaphoric expressions used by the writer of letters to editors of Suara Merdeka daily newspaper. This paper aims at elaborating how metaphoric expressions used in letters to editors of Suara Merdeka Daily Newspaper become a dynamic artefact of social values. To achieve the goal, this research uses nonparticipant observation for collecting data and purposive sampling techniques for selecting and choosing samples. The samples are the metaphoric expressions found in the letters to editors of Suara Merdeka Daily Newspaper written in the period of general elections of House of Representative Members (Pileg) in 2009. To analyze the data, this research uses referential method and abductive inferencial technique. Referential method is used to show and interpret the concepts represented by the metaphoric expressions, while the abductive inferencial technique is used to show the social values formulated in the concepts of the metaphors. The result shows that the social values inferenced from the metaphoric expressions that became the artefacts are related with what people do or behave, perceive, and experience in the connection with the general elections conducted, House of Representative candidate‘s personality and behavior, the role of the political parties, the fund to run the elections, campaign, people aspiration and voice, vote gathering, the fixed list of the voter, general elections committee. The dynamicity of the artefact is shown horizontally and vertically. The horizontal dynamicity is shown by the arrangement of different words representing experience, thought, and feeling in connection with what people experience in general election in 2009, while the vertical dynamicity is shown by the choice of the different words in the same category representing their experience related to the election. The experience changes through time leading to the dynamicity of the expressions used

Etude de marché: l'avenir du Centre sportif de Cointrin

Le centre sportif de Cointrin possède depuis 1962 la première piscine publique genevoise connue également sous le nom de la piscine des Ailes. Elle se nomme de la sorte car la société coopérative d’habitation « les Ailes » gère l’administration du centre. En réalité, le centre et plus particulièrement les entrées de la piscine ne suffisent pas à couvrir les charges. En conséquence, la piscine a besoin du soutien de la commune pour continuer son activité. L’objectif de ce travail est d’analyser la pérennité du centre et de connaître les éléments qui font que la piscine génère du déficit. En menant une étude de marché, il sera possible d’évaluer la stratégie à adapter et d’en ressortir des recommandations pour améliorer le résultat. Ce travail s’est donc déroulé en plusieurs étapes. La première consiste à la récolte d’informations déjà existantes, d’évaluer les éléments pouvant influencer la pérennité du centre, mais également à se focaliser sur l’état financier du centre afin de comprendre ses résultats négatifs. Pour terminer, nous mènerons une enquête en complémentarité. Cette étude a dévoilé l’intérêt croissant pour les activités sportives (la natation par exemple), tandis que les piscines ouvertes en été (comprenant un espace vert) sont plutôt considérées comme occasions de détente et de loisir. Le centre devrait alors axer ses diverses activités pour répondre à cette demande. Le centre sportif donne satisfaction à ses clients, cependant des points d’amélioration tel l’espace de jeux sont à considérer, il faut toutefois veiller à respecter l’harmonie avec la première activité recherchée à la piscine, c’est-à-dire, la détente

Analyse du contexte de formation d’un jeune athlète. Etude de cas

peer reviewedNous nous sommes intéressés à un jeune espoir sportif belge pour lequel nous avons tenté de modéliser la structure d’encadrement. Pour ce faire, nous avons opté pour des entretiens exploratoires semi‐directifs dans les milieux familial, sportif et scolaire de l’athlète. L’analyse des informations recueillies nous a permis de dévoiler la qualité de la structure actuellement mise en place et, notamment, le rôle déterminant du père qui se charge de coordonner et de contrôler l’ensemble de celle‐ci. Notre étude a également conscientisé les acteurs sur le fonctionnement de la structure et s’est montrée efficace pour améliorer les relations entre les principaux acteurs