MEDIA DEVELOPMENT LEARNING MODULE ASSEMBLY ON THE COMPUTER LESSONS FOR ICT IN CLASS X SMA N 1 BANTUL

The purpose of this study is to develop a new product in the form of a computer assembly module in SMA N 1 Bantul. Another purpose of this study was to determine the feasibility stage of development and computer module assembly in accordance with the Education Unit Level Curriculum (SBC) in SMA N 1 Bantul. The research method used is the method of research and development ((Research and Development)). New product development in the form of modules ICT subjects through several stages, namely (1) a preliminary study, (2) planning, (3) initial product development, (4) revision of the design, (5) initial field trials, (6) revision I , (7) main field trials; (8) revision II; (9) operational field trials; (10) revision of the final product, and (11) product improvement. The research was conducted at Grade X SMA N 1 Bantul. Data was collected using a questionnaire instrument. The analysis technique used is the qualitative and quantitative analysis to determine the feasibility of a computer assembly module. Results of this study was generated in the form of instructional media products shaped modules ICT subjects. Based on the syllabus, standards of competence and basic competences materials then developed into two (2) materials and learning activities. Subject matter of the module, namely (1) the introduction of hardware (hardware) computer, (2) assemble a computer. According to expert faculty assessment materials obtained an overall average score of 4.17 with a good assessment criteria, ICT teacher as expert material 1 1 earned an average overall score of 3.94 with a good assessment criteria, ICT teacher as expert material 2 2 obtained average The average overall score of 4 with good assessment criteria, from 1 media specialists earned an average overall score of 4.11 with a good assessment criteria, from 2 media specialists earned an average overall score of 3.89 with both criteria, and from field trials to obtain an average overall score of 4.10 with a good assessment criteria. Eligibility standard module when overall average score of not less than a minimum standard that is good. Based on these data it can be concluded that the computer module assembly in SMA N 1 Bantul are already well developed so worthy used to support learning activities. Keywords: modules, computer assembly

A 2-Question Summative Score Correlates with the Maslach Burnout Inventory

Introduction: There is a high prevalence of burnout among emergency medicine (EM) residents. The Maslach Burnout Inventory - Human Services Survey (MBI-HSS) is a widely used tool to measure burnout. The objective of this study was to compare the MBI-HSS and a two-question tool to determine burnout in the EM resident population.Methods: Based on data from the 2017 National Emergency Medicine Resident Wellness Survey study, we determined the correlation between two single-item questions with their respective MBI subscales and the full MBI-HSS. We then compared a 2-Question Summative Score to the full MBI-HSS with respect to primary, more restrictive, and more inclusive definitions of burnout previously reported in the literature.Results: Of 1,522 residents who completed the survey 37.0% reported “I feel burned out from my work,” and 47.1% reported “I have become more callous toward people since I took this job” once a week or more (each item >3 on a scale of 0-6). A 2-Question Summative Score totaling >3 correlated most closely with the primary definition of burnout (Spearman’s rho 0.65 [95% confidence interval 0.62-0.68]). Using the summative score, 77.7% of residents were identified as burned out, compared to 76.1% using the full MBI-HSS, with a sensitivity and specificity of 93.6% and 73.0%, respectively.Conclusion: An abbreviated 2-Question Summative Score correlates well with the full MBI-HSS tool in assessing EM resident physician burnout and could be considered a rapid screening tool to identify at-risk residents experiencing burnout

Quantification of Maceration Changes using Post Mortem MRI in Fetuses

BACKGROUND: Post mortem imaging is playing an increasingly important role in perinatal autopsy, and correct interpretation of imaging changes is paramount. This is particularly important following intra-uterine fetal death, where there may be fetal maceration. The aim of this study was to investigate whether any changes seen on a whole body fetal post mortem magnetic resonance imaging (PMMR) correspond to maceration at conventional autopsy. METHODS: We performed pre-autopsy PMMR in 75 fetuses using a 1.5 Tesla Siemens Avanto MR scanner (Erlangen, Germany). PMMR images were reported blinded to the clinical history and autopsy data using a numerical severity scale (0 = no maceration changes to 2 = severe maceration changes) for 6 different visceral organs (total 12). The degree of maceration at autopsy was categorized according to severity on a numerical scale (1 = no maceration to 4 = severe maceration). We also generated quantitative maps to measure the liver and lung T2. RESULTS: The mean PMMR maceration score correlated well with the autopsy maceration score (R(2) = 0.93). A PMMR score of ≥4.5 had a sensitivity of 91%, specificity of 64%, for detecting moderate or severe maceration at autopsy. Liver and lung T2 were increased in fetuses with maceration scores of 3-4 in comparison to those with 1-2 (liver p = 0.03, lung p = 0.02). CONCLUSIONS: There was a good correlation between PMMR maceration score and the extent of maceration seen at conventional autopsy. This score may be useful in interpretation of fetal PMMR

Early Wound Healing Score: a system to evaluate the early healing of periodontal soft tissue wounds

Purpose: Numerous indices have been proposed to analyse wound healing in oral soft tissues, but each has specific shortcomings. A new method of analysis, the Early Wound Healing Score (EHS), was evaluated in the present study. The aim was to assess more accurately early healing by primary intention of surgical incisions in periodontal soft tissues. Methods: Twenty-one patients were treated with different surgical procedures comprising 1 or 2 vertical releasing incisions as part of a surgical access flap. Twenty-four hours after surgery, early wound healing at the vertical releasing incisions was assessed using the EHS. This score assessed clinical signs of re-epithelialization (CSR), clinical signs of haemostasis (CSH), and clinical signs of inflammation (CSI). Since complete wound epithelialization was the main outcome, the CSR score was weighted to be 60% of the total final score. Accordingly, a score of 0, 3, or 6 points was possible for the assessment of CSR, whereas scores of 0, 1, or 2 points were possible for CSH and CSI. Higher values indicated better healing. Accordingly, the score for ideal early wound healing was 10. Results: Thirty vertical releasing incisions were assessed in 21 patients. At 24 hours after incision, 16 vertical releasing incisions (53.33%) received the maximum score of CSR, while 6 cases (20%) received an EHS of 10. None of the cases received 0 points. Conclusion: The EHS system may be a useful tool for assessing early wound healing in periodontal soft tissue by primary intention after surgery

Risk Model Development and Validation for Prediction of Coronary Artery Aneurysms in Kawasaki Disease in a North American Population.

Background Accurate prediction of coronary artery aneurysms ( CAAs ) in patients with Kawasaki disease remains challenging in North American cohorts. We sought to develop and validate a risk model for CAA prediction. Methods and Results A binary outcome of CAA was defined as left anterior descending or right coronary artery Z score ≥2.5 at 2 to 8 weeks after fever onset in a development cohort (n=903) and a validation cohort (n=185) of patients with Kawasaki disease. Associations of baseline clinical, laboratory, and echocardiographic variables with later CAA were assessed in the development cohort using logistic regression. Discrimination (c statistic) and calibration (Hosmer-Lemeshow) of the final model were evaluated. A practical risk score assigning points to each variable in the final model was created based on model coefficients from the development cohort. Predictors of CAAs at 2 to 8 weeks were baseline Z score of left anterior descending or right coronary artery ≥2.0, age <6 months, Asian race, and C-reactive protein ≥13 mg/ dL (c=0.82 in the development cohort, c=0.93 in the validation cohort). The CAA risk score assigned 2 points for baseline Z score of left anterior descending or right coronary artery ≥2.0 and 1 point for each of the other variables, with creation of low- (0-1), moderate- (2), and high- (3-5) risk groups. The odds of CAA s were 16-fold greater in the high- versus the low-risk groups in the development cohort (odds ratio, 16.4; 95% CI , 9.71-27.7 [ P<0.001]), and >40-fold greater in the validation cohort (odds ratio, 44.0; 95% CI, 10.8-180 [ P<0.001]). Conclusions Our risk model for CAA in Kawasaki disease consisting of baseline demographic, laboratory, and echocardiographic variables had excellent predictive utility and should undergo prospective testing

Increased risk for malaria in chronically malnourished children under 5 years of age in rural Gambia.

Malaria and malnutrition cause high morbidity and mortality in rural sub-Saharan Africa. To explore the relationship between nutritional status and malaria, a cohort of Gambian children under 5 years of age was followed weekly during one malaria season. Anthropometric measurements were made at the beginning and at the end of the season. A total of 55/107 (51.4 per cent) children with baseline stunting, defined as having a height-for-age z-score below -2 standard deviations, subsequently experienced malaria episodes, compared to 145/380 (38.2 per cent) children who were not stunted (RR = 1.35; 95 per cent CI, 1.08-1.69; p value = 0.01). Neither wasting (weight-for-height z-score below -2 standard deviations) nor undernutrition (weight-for-age z-score below -2 standard deviations) influenced susceptibility to malaria. Adjustment for characteristics of age, sex, and ethnicity did not significantly change the risk ratios. Malaria had no effect on the nutritional status from the beginning to the end of the malaria season. Our findings suggest that chronically malnourished children may be at higher risk for developing malaria episodes

Sublinear algorithms for local graph centrality estimation

We study the complexity of local graph centrality estimation, with the goal of approximating the centrality score of a given target node while exploring only a sublinear number of nodes/arcs of the graph and performing a sublinear number of elementary operations. We develop a technique, that we apply to the PageRank and Heat Kernel centralities, for building a low-variance score estimator through a local exploration of the graph. We obtain an algorithm that, given any node in any graph of $m$ arcs, with probability $(1-\delta)$ computes a multiplicative $(1\pm\epsilon)$-approximation of its score by examining only $\tilde{O}(\min(m^{2/3} \Delta^{1/3} d^{-2/3},\, m^{4/5} d^{-3/5}))$ nodes/arcs, where $\Delta$ and $d$ are respectively the maximum and average outdegree of the graph (omitting for readability $\operatorname{poly}(\epsilon^{-1})$ and $\operatorname{polylog}(\delta^{-1})$ factors). A similar bound holds for computational complexity. We also prove a lower bound of $\Omega(\min(m^{1/2} \Delta^{1/2} d^{-1/2}, \, m^{2/3} d^{-1/3}))$ for both query complexity and computational complexity. Moreover, our technique yields a $\tilde{O}(n^{2/3})$ query complexity algorithm for the graph access model of [Brautbar et al., 2010], widely used in social network mining; we show this algorithm is optimal up to a sublogarithmic factor. These are the first algorithms yielding worst-case sublinear bounds for general directed graphs and any choice of the target node.Comment: 29 pages, 1 figur

Individualized Angiotensin‐Converting Enzyme (ACE)‐Inhibitor Therapy in Stable Coronary Artery Disease Based on Clinical and Pharmacogenetic Determinants: The PERindopril GENEtic (PERGENE) Risk Model

Patients with stable coronary artery disease (CAD) constitute a heterogeneous group in which the treatment benefits by angiotensin-converting enzyme (ACE)-inhibitor therapy vary between individuals. Our objective was to integrate clinical and pharmacogenetic determinants in an ultimate combined risk prediction model.Clinical, genetic, and outcomes data were used from 8726 stable CAD patients participating in the EUROPA/PERGENE trial of perindopril versus placebo. Multivariable analysis of phenotype data resulted in a clinical risk score (range, 0-21 points). Three single-nucleotide polymorphisms (rs275651 and rs5182 in the angiotensin-II type I-receptor gene and rs12050217 in the bradykinin type I-receptor gene) were used to construct a pharmacogenetic risk score (PGXscore; range, 0-6 points). Seven hundred eighty-five patients (9.0%) experienced the primary endpoint of cardiovascular mortality, nonfatal myocardial infarction or resuscitated cardiac arrest, during 4.2 years of follow-up. Absolute risk reductions ranged from 1.2% to 7.5% in the 73.5% of patients with PGXscore of 0 to 2. As a consequence, estimated annual numbers needed to treat ranged from as low as 29 (clinical risk score ≥10 and PGXscore of 0) to 521 (clinical risk score ≤6 and PGXscore of 2). Furthermore, our data suggest that long-term perindopril prescription in patients with a PGXscore of 0 to 2 is cost-effective.Both baseline clinical phenotype, as well as genotype determine the efficacy of widely prescribed ACE inhibition in stable CAD. Integration of clinical and pharmacogenetic determinants in a combined risk prediction model demonstrated a very wide range of gradients of absolute treatment benefit

TECHNICAL DRAWING SKILL IMPROVEMENT WITH MEDIA PEMBELAJARAN MODUL GAMBAR TEKNIK FOR TECHNICAL DRAWING COURSE IN ENGINEERING DEPARTEMENT OF AUDIO VIDEO SMK NEGERI 2 YOGYAKARTA

The purpose of this research is to find out the design of Modul Gambar Teknik, describing the learning process of technical drawing through Media Pembelajaran Modul Gambar Teknik in exertion to improve the technical drawing skill. In addition the purpose of this research is to find out the outcomes of learning the technical drawing course using Media Pembelajaran Modul Gambar Teknik at the students of class 1TAV1 in SMK Negeri 2 Yogyakarta TA 2010/2011. This research method is using the Classroom Action Research (CAR) with the cycle model that implemented as collaborative and passive participative. Implementation of learning through Media Pembelajaran Modul Gambar Teknik in action is interpolated to the cycles of actions. The research was originally planned for 1 cycle, but in the realization it takes three cycles with the whole students of the class 1TAV1 from Audio Video Departement in SMK Negeri 2 Yogyakarta as the research subject with a population 36 students consisting of 26 male and 9 female. Meanwhile the technique of data collection is done through observation, field notes, questionnaires and document of the learning outcomes. These data were analyzed using analysis of Miles-Huberman, which is started from data collection, data reduction, data presentation until the conclusion of the research is obtained. The learning outcomes of technical drawing using Media Pembelajaran Modul Gambar Teknik based on the criteria of class’s average score 80,00 and KKM score 80,00, with students percentage above the KKM is 80,00% or approximately 29 students. In the first cycle, there are 11 (30,56%) students that get the score above the KKM (80,00) and 25 (69,44%) students that get the score below the target of KKM, with the treatment that given by the teacher is only the explanation of the module. Then in the 2nd cycle its become 15 (41,67%) students that get the score above the KKM (80,00) while the other students who still get their score below the KKM is 21 (58,33%), with the treatment of module explanation along with the distribution of the drawing samples in the finished form, and in the 3rd cycle there are 30 (83,33%) students that get the score above the KKM (80,00) while the other student who still get the score below the target of KKM is 6 (16,67%) students, with the treatment given by the teacher is module explanation, providing PCB samples in the finished form along with the video tutorial of job sheet 3. Meanwhile the completeness criteria of finishing the job (6x45 minutes) in the cycle 1, 2 and 3 all of the students completed in completing job sheet. There are improvements of the class’s average score from cycle 1 (75,92) become 77,89 in the cycle 2 or increased ↑1,96 (7,39%), while from cycle 2 to cycle 3 become 79,97 or increased ↑2,09 point (13,95%). From the score of the drawing that shows the improvement from cycle 1 to cycle 3, it can be concluded that the using of Modul Gambar Teknik to improve the drawing skill are reasonable to be used as a learning media