29,177 research outputs found

    Comparaci贸n de la actividad catal铆tica del complejo FePcCl16 inmovilizado en SiO2 y SBA-15 en la cin茅tica de producci贸n de carvona por oxidaci贸n al铆lica de limoneno con per贸xido de tert-butilo

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    Se evalu贸 la actividad catal铆tica de una ftalocianina de hierro hexadecoclorada (FePcCl16) soportada en SiO2 amorfa y SBA-15 con diferentes tama帽os de part铆cula y velocidades de agitaci贸n en la producci贸n de carvona a partir de limoneno con per贸xido de tert-butilo (TBHP). Los resultados mostraron que, a 40掳C, el aumento de la velocidad de agitaci贸n y la disminuci贸n del tama帽o de part铆cula del catalizador favorecen la producci贸n de carvona con ambos soportes. La mejor actividad catal铆tica se observ贸 con el complejo inmovilizado en SiO2 amorfa, obteni茅ndose -rlimoneno = 1,101 mmol/gcat-min y rcarvona = 0,212 mmol/gcat-min a 40 掳C, 875 rpm, tama帽o de part铆cula del catalizador menor a 90 渭m y 30 min de reacci贸n.Departamento Administrativo de Ciencia, Tecnolog铆a e Innovaci贸n [CO] Colciencias5507-543-31904Programa: Bioprospecci贸n y desarrollo de ingredientes naturales para las industrias cosm茅tica, farmac茅utica y de productos de aseo con base en la biodiversidad colombianan

    Small newborns in post-conflict Northern Uganda: Burden and interventions for improved outcomes

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    Introduction: A small newborn can be the result of either a low birthweight (LBW), or a preterm birth (PB), or both. LBW can be due to either a preterm appropriate-for gestational-age (preterm-AGA), or a term small-for-gestational age (term-SGA) or intrauterine growth restriction (IUGR). An IUGR is a limited in-utero foetal growth rates or foetal weight < 10th percentile. Small newborns have an increased risk of dying, particularly in low-resource settings. We set out to assess the burden, the modifiable risk factors and health outcomes of small newborns in the post-conflict Northern Ugandan district of Lira. In addition, we studied the use of video-debriefing when training health staff in Helping Babies Breathe. Subjects and methods: In 2018-19, we conducted a community-based cohort study on 1556 mother-infant dyads, nested within a cluster randomized trial. In our cohort study, we estimated the incidence and risk factors for LBW and PB and the association of LBW with severe outcomes. We explored the prevalence of and factors associated with neonatal hypoglycaemia, as well as any association between neonatal death and hypoglycaemia. In addition, we conducted a cluster randomized trial to compare Helping Babies Breathe (HBB) training in combination with video debriefing to the traditional HBB training alone on the attainment and retention of health worker neonatal resuscitation competency. Results: The incidence of LBW and PB in our cohort was lower than the global estimates, 7.3% and 5.0%, respectively. Intermittent preventive treatment for malaria was associated with a reduced risk of LBW. HIV infection was associated with an increased risk of both LBW and PB, while maternal formal education (schooling) of 鈮7 years was associated with a reduced risk of LBW and PB. The proportions of neonatal deaths were many-folds higher among LBW infants compared to their non-LBW counterparts. The proportion of neonatal deaths among LBW was 103/1000 live births compared to 5/1000 among the non-LBW. The prevalence of neonatal hypoglycaemia in our cohort was 2.5%. LBW and PB each independently were associated with an increased risk of neonatal hypoglycaemia. Neonatal hypoglycaemia was associated with an increased risk of hospitalisation and severe outcomes. We demonstrated that neonatal resuscitation training with video debriefing, improved competence attainment and retention among health workers, compared to traditional HBB training alone. Conclusion: In northern Uganda, small infants still have a many-fold higher risk of dying compared to normal infants. In addition, small infants are also at more risk of neonatal hypoglycaemia compared to normal infants. Efforts are needed to secure essential newborn care, should we reach the target of Sustainable Development Goal number 3.2 of reducing infant mortality to less than 12/1000 live births by 2030

    孝械芯褉褨褟 褋懈褋褌械屑 屑芯斜褨谢褜薪懈褏 褨薪褎芯泻芯屑褍薪褨泻邪褑褨泄. 小懈褋褌械屑薪邪 邪褉褏褨褌械泻褌褍褉邪

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    袧邪胁褔邪谢褜薪懈泄 锌芯褋褨斜薪懈泻 屑褨褋褌懈褌褜 芯锌懈褋 谢芯谐褨褔薪懈褏 褌邪 褎褨蟹懈褔薪懈褏 褋褌褉褍泻褌褍褉, 锌褉芯褑械写褍褉, 邪谢谐芯褉懈褌屑褨胁, 锌褉芯褌芯泻芯谢褨胁, 锌褉懈薪褑懈锌褨胁 锌芯斜褍写芯胁懈 褨 褎褍薪泻褑褨芯薪褍胁邪薪薪褟 屑械褉械卸 褋褌褨谢褜薪懈泻芯胁芯谐芯 屑芯斜褨谢褜薪芯谐芯 蟹胁鈥櫻徯沸貉 (写芯 3G) 褨 屑芯斜褨谢褜薪懈褏 褨薪褎芯泻芯屑褍薪褨泻邪褑褨泄 (4G 褨 胁懈褖械), 锌褉懈写褨谢褟褞褔懈 褍胁邪谐褍 褉芯蟹谐谢褟写褍 蟹邪谐邪谢褜薪懈褏 邪褉褏褨褌械泻褌褍褉 屑械褉械卸 芯锌械褉邪褌芯褉褨胁 屑芯斜褨谢褜薪芯谐芯 蟹胁鈥櫻徯沸貉, 褩褏 褍锌褉邪胁谢褨薪薪褟 褨 泻芯芯褉写懈薪褍胁邪薪薪褟, 薪械锌械褉械褉胁薪芯褋褌褨 械胁芯谢褞褑褨褩 褉芯蟹胁懈褌泻褍 蟹邪褋芯斜褨胁 褎褍薪泻褑褨芯薪褍胁邪薪薪褟 褨 褋锌芯褋芯斜褨胁 薪邪写邪薪薪褟 锌芯褋谢褍谐 褌邪泻懈褏 屑械褉械卸. 袩芯褋褨斜薪懈泻 褋褌褉褍泻褌褍褉薪芯 屑邪褦 褋褨屑 褉芯蟹写褨谢褨胁 褨 锌芯斜褍写芯胁邪薪懈泄 褌邪泻, 褖芯 褋泻谢邪写薪褨褋褌褜 屑邪褌械褉褨邪谢褍 蟹褉芯褋褌邪褦 蟹 泻芯卸薪懈屑 薪邪褋褌褍锌薪懈屑 褉芯蟹写褨谢芯屑. 袧邪胁褔邪谢褜薪懈泄 锌芯褋褨斜薪懈泻 锌褉懈蟹薪邪褔械薪芯 写谢褟 蟹写芯斜褍胁邪褔褨胁 褋褌褍锌械薪褟 斜邪泻邪谢邪胁褉邪 蟹邪 褋锌械褑褨邪谢褜薪褨褋褌褞 172 芦孝械谢械泻芯屑褍薪褨泻邪褑褨褩 褌邪 褉邪写褨芯褌械褏薪褨泻邪禄, 斜褍写械 褌邪泻芯卸 泻芯褉懈褋薪懈屑 写谢褟 邪褋锌褨褉邪薪褌褨胁, 薪邪褍泻芯胁懈褏 褌邪 褨薪卸械薪械褉薪芯-褌械褏薪褨褔薪懈褏 锌褉邪褑褨胁薪懈泻褨胁 蟹邪 薪邪锌褉褟屑芯屑 褨薪褎芯褉屑邪褑褨泄薪芯-褌械谢械泻芯屑褍薪褨泻邪褑褨泄薪懈褏 褋懈褋褌械屑 褌邪 褌械褏薪芯谢芯谐褨泄.The manual contains a description of the logical and physical structures, procedures, algorithms, protocols, principles of construction and operation of cellular networks for mobile communications (up to 3G) and mobile infocommunications (4G and higher), paying attention to the consideration of general architectures of mobile operators' networks, their management, and coordination, the continuous evolution of the development of the means of operation and methods of providing services of such networks. The manual has seven structural sections and is structured in such a way that the complexity of the material increases with each subsequent chapter. The textbook is intended for applicants for a bachelor's degree in specialty 172 "Telecommunications and Radio Engineering", and will also be useful to graduate students, and scientific and engineering workers in the direction of information and telecommunication systems and technologies

    Use of Nanostructured Silica SBA-15 as an Oral Vaccine Adjuvant to Control <i>Mycoplasma hyopneumoniae</i> in Swine Production

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    Mycoplasma hyopneumoniae is a difficult-to-control bacterium since commercial vaccines do not prevent colonization and excretion. The present study aimed to evaluate the performance of an orally administered vaccine composed of antigens extracted from Mycoplasma hyopneumoniae and incorporated into mesoporous silica (SBA-15), which has an adjuvant-carrier function, aiming to potentiate the action of the commercial intramuscular vaccine. A total of 60 piglets were divided into four groups (n = 15) submitted to different vaccination protocols as follows, Group 1: oral SBA15 + commercial vaccine at 24 days after weaning, G2: oral vaccine on the third day of life + vaccine commercial vaccine at 24 days, G3: commercial vaccine at 24 days, and G4: commercial vaccine + oral vaccine at 24 days. On the first day, the piglets were weighed and, from the third day onwards, submitted to blood collections for the detection and quantification of anti-Mycoplasma hyopneumoniae IgG. Nasal swabs were collected to monitor IgA by ELISA, and oropharyngeal swabs were used to assess the bacterial load by qPCR. Biological samples were collected periodically from the third day of life until the 73rd day. At 41 days of life, 15 individuals of the same age, experimentally challenged with an inoculum containing M. hyopneumoniae, were co-housed with the animals from groups (1 to 4) in a single pen to increase the infection pressure during the nursery period. At 73 days, all piglets were euthanized, and lungs were evaluated by collecting samples for estimation of bacterial load by qPCR. Quantitative data obtained from physical parameters and laboratory investigation were analyzed by performing parametric or non-parametric statistical tests. Results indicate that animals from G2 showed smaller affected lung areas compared to G3. Animals from G2 and G4 had a low prevalence of animals shedding M. hyopneumoniae at 61 days of age. Additionally, no correlation was observed between lung lesions and M. hyopneumoniae load in lung and BALF samples in animals that received the oral vaccine, while a strong correlation was observed in other groups. In the present study, evidence points to the effectiveness of the oral vaccine developed for controlling M. hyopneumoniae in pig production under field conditions

    Explicit spectral gap for Schottky subgroups of SL(2,Z)\mathrm{SL} (2,\mathbb{Z})

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    Let \Gamma be a Schottky subgroup of SL(2,Z)\mathrm{SL} (2,\mathbb{Z}). We establish a uniform and explicit lower bound of the second eigenvalue of the Laplace-Beltrami operator of congruence coverings of the hyperbolic surface \H2\Gamma \backslash \mathbb{H}^2 provided the limit set of \Gamma is thick enough.Comment: 31 page

    Iron Oxide Nanoparticles and Nano-Composites: An Efficient Tool for Cancer Theranostics

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    In recent years, functional Iron oxides nanoparticles and nano-composites have gained a special traction in the field of nano-biomedicine, owing to their multifunctional capabilities that includes the inherent magnetic resonance imaging, magnetic bioseparation, cargo delivery and magnetic hyperthermia behavior. Interestingly, there are various forms of iron oxides available, with each form having their own specific characteristics. The different polymorphic forms of iron oxides are obtained through various synthetic routes and are usually surface modified to prevent their oxidation. The chapter shall encompass the synthesis and surface modification of Iron oxides nanoparticles, physicochemical properties, and theranostic application of the magnetic iron oxide nanoparticles in cancer. Also, the future directions of Iron oxide nanoparticles and nano-composites towards the achievement of clinically realizable nanoformulation for cancer theranostic applications were highlighted