450 research outputs found

    Two Novel Retinal Blood Vessel Segmentation Algorithms

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    Assessment of blood vessels in retinal images is an important factor for many medical disorders. The changes in the retinal vessels due to the pathologies can be easily identified by segmenting the retinal vessels. Segmentation of retinal vessels is done to identify the early diagnosis of the disease like glaucoma, diabetic retinopathy, macular degeneration, hypertensive retinopathy and arteriosclerosis. In this paper, we propose two automatic blood vessel segmentation methods. The first proposed algorithm starts with the extraction of blood vessel centerline pixels. The final segmentation is obtained using an iterative region growing method that merges the contents of several binary images resulting from vessel width dependent modified morphological filters on normalized retinal images. In the second proposed algorithm the blood vessel is segmented using normalized modified morphological operations and neuro fuzzy classifier. Normalized morphological operations are used to enhance the vessels and neuro fuzzy classifier is used to segment retinal blood vessels. These methods are applied on the publicly available DRIVE database and the experimental results obtained by using green channel images have been presented and their results are compared with recently published methods. The results demonstrate that our algorithms are very effective methods to detect retinal blood vessels.DOI:http://dx.doi.org/10.11591/ijece.v4i3.582

    Segmentation Of Retinal Blood Vessels Using A Novel Fuzzy Logic Algorithm

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    In this work, a rule-based method is presented for blood vessel segmentation in digital retinal images. This method can be used in computer analyses of retinal images, e.g., in automated screening for diabetic retinopathy. Diabetic retinopathy is the most common diabetic eye disease and a leading cause of blindness. Diagnosis of diabetic retinopathy at an early stage can be done through the segmentation of the blood vessels of retina. Many studies have been carried out in the last decade in order to obtain accurate blood vessel segmentation in retinal images including supervised and rule-based methods. This method uses eight feature vectors for each pixel. These features are means and medians of intensity values of pixel itself, first and second nearest neighbor at four directions. Features are used in fuzzy logic algorithm as crisp input. The final segmentation is obtained using a thresholding method. The method was tested on the publicly available database DRIVE and its results are compared with distinguished published methods. Our method achieved an average accuracy of 93.82% and an area under the receiver operating characteristic curve of 94.19% for DRIVE database. Our results demonstrated an average sensitivity of 72.28% and a specificity of 97.04%. The calculated sensitivity and specificity values for DRIVE database also state that the proposed segmentation method is effective and robust

    A Novel Retinal Blood Vessel Segmentation Algorithm using Fuzzy segmentation

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    Assessment of blood vessels in retinal images is an important factor for many medical disorders. The changes in the retinal vessels due to the pathologies can be easily identified by segmenting the retinal vessels. Segmentation of retinal vessels is done to identify the early diagnosis of the disease like glaucoma, diabetic retinopathy, macular degeneration, hypertensive retinopathy and arteriosclerosis. In this paper, we propose an automatic blood vessel segmentation method. The proposed algorithm starts with the extraction of blood vessel centerline pixels. The final segmentation is obtained using an iterative region growing method that merges the binary images resulting from centerline detection part with the image resulting from fuzzy vessel segmentation part. In this proposed algorithm, the blood vessel is enhanced using modified morphological operations and the salt and pepper noises are removed from retinal images using Adaptive Fuzzy Switching Median filter. This method is applied on two publicly available databases, the DRIVE and the STARE and the experimental results obtained by using green channel images have been presented and compared with recently published methods. The results demonstrate that our algorithm is very effective method to detect retinal blood vessels.DOI:http://dx.doi.org/10.11591/ijece.v4i4.625

    Human Treelike Tubular Structure Segmentation: A Comprehensive Review and Future Perspectives

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    Various structures in human physiology follow a treelike morphology, which often expresses complexity at very fine scales. Examples of such structures are intrathoracic airways, retinal blood vessels, and hepatic blood vessels. Large collections of 2D and 3D images have been made available by medical imaging modalities such as magnetic resonance imaging (MRI), computed tomography (CT), Optical coherence tomography (OCT) and ultrasound in which the spatial arrangement can be observed. Segmentation of these structures in medical imaging is of great importance since the analysis of the structure provides insights into disease diagnosis, treatment planning, and prognosis. Manually labelling extensive data by radiologists is often time-consuming and error-prone. As a result, automated or semi-automated computational models have become a popular research field of medical imaging in the past two decades, and many have been developed to date. In this survey, we aim to provide a comprehensive review of currently publicly available datasets, segmentation algorithms, and evaluation metrics. In addition, current challenges and future research directions are discussed.Comment: 30 pages, 19 figures, submitted to CBM journa

    Automated Detection of Retinal Hemorrhage based on Supervised Classifiers

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    Supervised machine learning algorithm based retinal hemorrhage detection and classification is presented. For developing an automated diabetic retinopathy screening system, efficient detection of retinal hemorrhage is important. Splat, which is a high level entity in image segmentation is used to mark out hemorrhage in the pre-processed fundus image. Here, color images of retina are portioned into different segments (splats) covereing the whole image. With the help of splat level and GLCM features extracted from the splats, three classifiers are trained and tested using the relevant features. The ground-truth is established with the help of a retinal expert and using dataset and clinical images the validation was done. The output obtained using the three classifiers had more than 96 % sensitivity and accuracy

    Detection of Macula and Recognition of Aged-Related Macular Degeneration in Retinal Fundus Images

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    In aged people, the central vision is affected by Age-Related Macular Degeneration (AMD). From the digital retinal fundus images, AMD can be recognized because of the existence of Drusen, Choroidal Neovascularization (CNV), and Geographic Atrophy (GA). It is time-consuming and costly for the ophthalmologists to monitor fundus images. A monitoring system for automated digital fundus photography can reduce these problems. In this paper, we propose a new macula detection system based on contrast enhancement, top-hat transformation, and the modified Kirsch template method. Firstly, the retinal fundus image is processed through an image enhancement method so that the intensity distribution is improved for finer visualization. The contrast-enhanced image is further improved using the top-hat transformation function to make the intensities level differentiable between the macula and different sections of images. The retinal vessel is enhanced by employing the modified Kirsch's template method. It enhances the vasculature structures and suppresses the blob-like structures. Furthermore, the OTSU thresholding is used to segment out the dark regions and separate the vessel to extract the candidate regions. The dark region and the background estimated image are subtracted from the extracted blood vessels image to obtain the exact location of the macula. The proposed method applied on 1349 images of STARE, DRIVE, MESSIDOR, and DIARETDB1 databases and achieved the average sensitivity, specificity, accuracy, positive predicted value, F1 score, and area under curve of 97.79 %, 97.65 %, 97.60 %, 97.38 %, 97.57 %, and 96.97 %, respectively. Experimental results reveal that the proposed method attains better performance, in terms of visual quality and enriched quantitative analysis, in comparison with eminent state-of-the-art methods

    Human treelike tubular structure segmentation: A comprehensive review and future perspectives

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    Various structures in human physiology follow a treelike morphology, which often expresses complexity at very fine scales. Examples of such structures are intrathoracic airways, retinal blood vessels, and hepatic blood vessels. Large collections of 2D and 3D images have been made available by medical imaging modalities such as magnetic resonance imaging (MRI), computed tomography (CT), Optical coherence tomography (OCT) and ultrasound in which the spatial arrangement can be observed. Segmentation of these structures in medical imaging is of great importance since the analysis of the structure provides insights into disease diagnosis, treatment planning, and prognosis. Manually labelling extensive data by radiologists is often time-consuming and error-prone. As a result, automated or semi-automated computational models have become a popular research field of medical imaging in the past two decades, and many have been developed to date. In this survey, we aim to provide a comprehensive review of currently publicly available datasets, segmentation algorithms, and evaluation metrics. In addition, current challenges and future research directions are discussed
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