3 research outputs found
Mesh-to-raster based non-rigid registration of multi-modal images
Region of interest (ROI) alignment in medical images plays a crucial role in
diagnostics, procedure planning, treatment, and follow-up. Frequently, a model
is represented as triangulated mesh while the patient data is provided from CAT
scanners as pixel or voxel data. Previously, we presented a 2D method for
curve-to-pixel registration. This paper contributes (i) a general
mesh-to-raster (M2R) framework to register ROIs in multi-modal images; (ii) a
3D surface-to-voxel application, and (iii) a comprehensive quantitative
evaluation in 2D using ground truth provided by the simultaneous truth and
performance level estimation (STAPLE) method. The registration is formulated as
a minimization problem where the objective consists of a data term, which
involves the signed distance function of the ROI from the reference image, and
a higher order elastic regularizer for the deformation. The evaluation is based
on quantitative light-induced fluoroscopy (QLF) and digital photography (DP) of
decalcified teeth. STAPLE is computed on 150 image pairs from 32 subjects, each
showing one corresponding tooth in both modalities. The ROI in each image is
manually marked by three experts (900 curves in total). In the QLF-DP setting,
our approach significantly outperforms the mutual information-based
registration algorithm implemented with the Insight Segmentation and
Registration Toolkit (ITK) and Elastix
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Mobile depth sensing technology and algorithms with application to occupational therapy healthcare
This thesis was submitted for the award of Doctor of Philosophy and was awarded by Brunel University LondonThe UK government is striving to shift its current healthcare delivery model from clini-cian–oriented services, to that of patient and self–care–oriented intervention strategies. It seeks to do so through Information Communication (ICT) and Computer Mediated Re-ality Technologies (CMRT) as a key strategy to overcome the ever–increasing scarcity of healthcare resources and costs. To this end, in the UK the use of paper–based information systems have exhibited their limitations in providing apposite care. At the national level, The Royal College of Occupational Therapists (RCOT) identify home visits and modifica-tions as key levers in a multifactorial health programme to evaluate interventions for older people with a history of falling or are identified as being prone to falling. Prescribing Assistive Equipment (AE) is one such mechanism that seeks to reduce the risk of falling whilst promoting the continued independence of physical dexterity and mobility in older adults at home. In the UK, the yearly cost of falls is estimated at £2.3 billion. Further evidence places a 30% to 60% abandonment rate on prescribed AE by and large due to a ‘poor fit’ and measurement inaccuracies.
To remain aligned with the national strategy, and assist in the eradication of measurement inaccuracies, this thesis employs Mobile Depth Sensing and Motion Track-ing Devices (MDSMTDs) to assist OTs in in the process of digitally measuring the extrin-sic fall–risk factors for the provision of AE. The quintessential component in this assess-ment lies in the measurement of fittings and furniture items in the home. To digitise and aid in this process, the artefact presented in this thesis employs stereo computer–vision and camera calibration algorithms to extract edges in 3D space. It modifies the Sobel–Feldman convolution filter by reducing the magnitude response and employs the camera intrinsic parameters as a mechanism to calculate the distortion matrix for interpolation between the edges and the 3D point cloud. Further Augmented Reality User Experience (AR-UX) facets are provided to digitise current state of the art clinical guidance and over-lay its instructions onto the real world (i.e., 3D space).
Empirical mixed methods assessment revealed that in terms of accuracy, the arte-fact exhibited enhanced performance gains over current paper–based guidance. In terms of accuracy consistency, the artefact can rectify measurement consistency inaccuracies, but there are still a wide range of factors that can influence the integrity of the point-cloud in respect of the device’s point-of-view, holding positions and measurement speed. To this end, OTs usability, and adoption preferences materialise in favour of the artefact. In conclusion, this thesis demonstrates that MDSMTDs are a promising alterna-tive to existing paper–based measurement practices as OTs appear to prefer the digital–based system and that they can take measurements more efficiently and accurately