6,280 research outputs found
Social and behavioral determinants of health in the era of artificial intelligence with electronic health records: A scoping review
Background: There is growing evidence that social and behavioral determinants
of health (SBDH) play a substantial effect in a wide range of health outcomes.
Electronic health records (EHRs) have been widely employed to conduct
observational studies in the age of artificial intelligence (AI). However,
there has been little research into how to make the most of SBDH information
from EHRs. Methods: A systematic search was conducted in six databases to find
relevant peer-reviewed publications that had recently been published. Relevance
was determined by screening and evaluating the articles. Based on selected
relevant studies, a methodological analysis of AI algorithms leveraging SBDH
information in EHR data was provided. Results: Our synthesis was driven by an
analysis of SBDH categories, the relationship between SBDH and
healthcare-related statuses, and several NLP approaches for extracting SDOH
from clinical literature. Discussion: The associations between SBDH and health
outcomes are complicated and diverse; several pathways may be involved. Using
Natural Language Processing (NLP) technology to support the extraction of SBDH
and other clinical ideas simplifies the identification and extraction of
essential concepts from clinical data, efficiently unlocks unstructured data,
and aids in the resolution of unstructured data-related issues. Conclusion:
Despite known associations between SBDH and disease, SBDH factors are rarely
investigated as interventions to improve patient outcomes. Gaining knowledge
about SBDH and how SBDH data can be collected from EHRs using NLP approaches
and predictive models improves the chances of influencing health policy change
for patient wellness, and ultimately promoting health and health equity.
Keywords: Social and Behavioral Determinants of Health, Artificial
Intelligence, Electronic Health Records, Natural Language Processing,
Predictive ModelComment: 32 pages, 5 figure
Utilizing Temporal Information in The EHR for Developing a Novel Continuous Prediction Model
Type 2 diabetes mellitus (T2DM) is a nation-wide prevalent chronic condition, which includes direct and indirect healthcare costs. T2DM, however, is a preventable chronic condition based on previous clinical research. Many prediction models were based on the risk factors identified by clinical trials. One of the major tasks of the T2DM prediction models is to estimate the risks for further testing by HbA1c or fasting plasma glucose to determine whether the patient has or does not have T2DM because nation-wide screening is not cost-effective.
Those models had substantial limitations on data quality, such as missing values. In this dissertation, I tested the conventional models which were based on the most widely used risk factors to predict the possibility of developing T2DM. The AUC was an average of 0.5, which implies the conventional model cannot be used to screen for T2DM risks. Based on this result, I further implemented three types of temporal representations, including non-temporal representation, interval-temporal representation, and continuous-temporal representation for building the T2DM prediction model. According to the results, continuous-temporal representation had the best performance. Continuous-temporal representation was based on deep learning methods. The result implied that the deep learning method could overcome the data quality issue and could achieve better performance.
This dissertation also contributes to a continuous risk output model based on the seq2seq model. This model can generate a monotonic increasing function for a given patient to predict the future probability of developing T2DM. The model is workable but still has many limitations to overcome.
Finally, this dissertation demonstrates some risks factors which are underestimated and are worthy for further research to revise the current T2DM screening guideline. The results were still preliminary. I need to collaborate with an epidemiologist and other fields to verify the findings. In the future, the methods for building a T2DM prediction model can also be used for other prediction models of chronic conditions
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