Peptide mass fingerprinting using field-programmable gate arrays

The reconfigurable computing paradigm, which exploits the flexibility and versatility of field-programmable gate arrays (FPGAs), has emerged as a powerful solution for speeding up time-critical algorithms. This paper describes a reconfigurable computing solution for processing raw mass spectrometric data generated by MALDI-TOF instruments. The hardware-implemented algorithms for denoising, baseline correction, peak identification, and deisotoping, running on a Xilinx Virtex-2 FPGA at 180 MHz, generate a mass fingerprint that is over 100 times faster than an equivalent algorithm written in C, running on a Dual 3-GHz Xeon server. The results obtained using the FPGA implementation are virtually identical to those generated by a commercial software package MassLynx

Reconfigurable Security: Edge Computing-based Framework for IoT

In various scenarios, achieving security between IoT devices is challenging since the devices may have different dedicated communication standards, resource constraints as well as various applications. In this article, we first provide requirements and existing solutions for IoT security. We then introduce a new reconfigurable security framework based on edge computing, which utilizes a near-user edge device, i.e., security agent, to simplify key management and offload the computational costs of security algorithms at IoT devices. This framework is designed to overcome the challenges including high computation costs, low flexibility in key management, and low compatibility in deploying new security algorithms in IoT, especially when adopting advanced cryptographic primitives. We also provide the design principles of the reconfigurable security framework, the exemplary security protocols for anonymous authentication and secure data access control, and the performance analysis in terms of feasibility and usability. The reconfigurable security framework paves a new way to strength IoT security by edge computing.Comment: under submission to possible journal publication

Reconfigurable Computing for Speech Recognition: Preliminary Findings

Continuous real-time speech recognition is a highly computationally-demanding task, but one which can take good advantage of a parallel processing system. To this end, we describe proposals for, and preliminary findings of, research in implementing in programmable logic the decoder part of a speech recognition system. Recognition via Viterbi decoding of Hidden Markov Models is outlined, along with details of current implementations, which aim to exploit properties of the algorithm that could make it well-suited for devices such as FPGAs. The question of how to deal with limited resources, by reconfiguration or otherwise, is also addressed