Adversarial Deformation Regularization for Training Image Registration Neural Networks

We describe an adversarial learning approach to constrain convolutional neural network training for image registration, replacing heuristic smoothness measures of displacement fields often used in these tasks. Using minimally-invasive prostate cancer intervention as an example application, we demonstrate the feasibility of utilizing biomechanical simulations to regularize a weakly-supervised anatomical-label-driven registration network for aligning pre-procedural magnetic resonance (MR) and 3D intra-procedural transrectal ultrasound (TRUS) images. A discriminator network is optimized to distinguish the registration-predicted displacement fields from the motion data simulated by finite element analysis. During training, the registration network simultaneously aims to maximize similarity between anatomical labels that drives image alignment and to minimize an adversarial generator loss that measures divergence between the predicted- and simulated deformation. The end-to-end trained network enables efficient and fully-automated registration that only requires an MR and TRUS image pair as input, without anatomical labels or simulated data during inference. 108 pairs of labelled MR and TRUS images from 76 prostate cancer patients and 71,500 nonlinear finite-element simulations from 143 different patients were used for this study. We show that, with only gland segmentation as training labels, the proposed method can help predict physically plausible deformation without any other smoothness penalty. Based on cross-validation experiments using 834 pairs of independent validation landmarks, the proposed adversarial-regularized registration achieved a target registration error of 6.3 mm that is significantly lower than those from several other regularization methods.Comment: Accepted to MICCAI 201

Data-driven weight optimization for real-time mesh deformation

3D model deformation has been an active research topic in geometric processing. Due to its efficiency, linear blend skinning (LBS) and its follow-up methods are widely used in practical applications as an efficient method for deforming vector images, geometric models and animated characters. LBS needs to determine the control handles and specify their influence weights, which requires expertise and is time-consuming. Further studies have proposed a method for efficiently calculating bounded biharmonic weights of given control handles which reduces user effort and produces smooth deformation results. The algorithm defines a high-order shape-aware smoothness function which tends to produce smooth deformation results, but fails to generate locally rigid deformations. To address this, we propose a novel data-driven approach to producing improved weights for handles that makes full use of available 3D model data by optimizing an energy consisting of data-driven, rigidity and sparsity terms, while maintaining its advantage of allowing handles of various forms. We further devise an efficient iterative optimization scheme. Through contrast experiments, it clearly shows that linear blend skinning based on our optimized weights better reflects the deformation characteristics of the model, leading to more accurate deformation results, outperforming existing methods. The method also retains real-time performance even with a large number of deformation examples. Our ablation experiments also show that each energy term is essential

Higher-Order Momentum Distributions and Locally Affine LDDMM Registration

To achieve sparse parametrizations that allows intuitive analysis, we aim to represent deformation with a basis containing interpretable elements, and we wish to use elements that have the description capacity to represent the deformation compactly. To accomplish this, we introduce in this paper higher-order momentum distributions in the LDDMM registration framework. While the zeroth order moments previously used in LDDMM only describe local displacement, the first-order momenta that are proposed here represent a basis that allows local description of affine transformations and subsequent compact description of non-translational movement in a globally non-rigid deformation. The resulting representation contains directly interpretable information from both mathematical and modeling perspectives. We develop the mathematical construction of the registration framework with higher-order momenta, we show the implications for sparse image registration and deformation description, and we provide examples of how the parametrization enables registration with a very low number of parameters. The capacity and interpretability of the parametrization using higher-order momenta lead to natural modeling of articulated movement, and the method promises to be useful for quantifying ventricle expansion and progressing atrophy during Alzheimer's disease

Parametric editing of clothed 3D avatars

Easy editing of a clothed 3D human avatar is central to many practical applications. However, it is easy to produce implausible, unnatural looking results, since subtle reshaping or pose alteration of avatars requires global consistency and agreement with human anatomy. Here, we present a parametric editing system for a clothed human body, based on use of a revised SCAPE model. We show that the parameters of the model can be estimated directly from a clothed avatar, and that it can be used as a basis for realistic, real-time editing of the clothed avatar mesh via a novel 3D body-aware warping scheme. The avatar can be easily controlled by a few semantically meaningful parameters, 12 biometric attributes controlling body shape, and 17 bones controlling pose. Our experiments demonstrate that our system can interactively produce visually pleasing results

A Revisit of Shape Editing Techniques: from the Geometric to the Neural Viewpoint

3D shape editing is widely used in a range of applications such as movie production, computer games and computer aided design. It is also a popular research topic in computer graphics and computer vision. In past decades, researchers have developed a series of editing methods to make the editing process faster, more robust, and more reliable. Traditionally, the deformed shape is determined by the optimal transformation and weights for an energy term. With increasing availability of 3D shapes on the Internet, data-driven methods were proposed to improve the editing results. More recently as the deep neural networks became popular, many deep learning based editing methods have been developed in this field, which is naturally data-driven. We mainly survey recent research works from the geometric viewpoint to those emerging neural deformation techniques and categorize them into organic shape editing methods and man-made model editing methods. Both traditional methods and recent neural network based methods are reviewed

Registration of 3D Point Clouds and Meshes: A Survey From Rigid to Non-Rigid

Three-dimensional surface registration transforms multiple three-dimensional data sets into the same coordinate system so as to align overlapping components of these sets. Recent surveys have covered different aspects of either rigid or nonrigid registration, but seldom discuss them as a whole. Our study serves two purposes: 1) To give a comprehensive survey of both types of registration, focusing on three-dimensional point clouds and meshes and 2) to provide a better understanding of registration from the perspective of data fitting. Registration is closely related to data fitting in which it comprises three core interwoven components: model selection, correspondences and constraints, and optimization. Study of these components 1) provides a basis for comparison of the novelties of different techniques, 2) reveals the similarity of rigid and nonrigid registration in terms of problem representations, and 3) shows how overfitting arises in nonrigid registration and the reasons for increasing interest in intrinsic techniques. We further summarize some practical issues of registration which include initializations and evaluations, and discuss some of our own observations, insights and foreseeable research trends