Residual Stress in Wheels: Comparison of Neutron Diffraction and Ultrasonic Methods, with Trends in RCF

The critical damage mechanism on many GB passenger train wheels is Rolling Contact Fatigue (RCF) cracking in the rim. Evidence from field observations suggests that RCF damage occurs much more quickly as the wheelsets near the end of their life. Wheel manufacturing processes induce a compressive hoop stress in the wheel rim; variations in residual stress through the life of a wheel may influence the observed RCF damage rates. This paper describes experiments to measure residual stresses in new and used wheel rims to identify whether this could be a significant factor, and compares the findings from neutron diffraction and ultrasonic birefringence methods. The scope goes beyond previous applications of neutron diffraction to railway wheels and identifies key considerations for future testing. Assuming that the as-manufactured stress distribution was similar for all three wheels tested, it is found that the stresses are redistributed within the wheel rim during its life as material is removed and plastic flow occurs. However, the hoop stress near the running surface remains compressive and may not have a large influence on the RCF damage rates

High sensitivity micro-fiber Mach-Zehnder interferometric temperature sensors with a high index ring layer

The influence of the high index ring layer (HIRL) in a tapered fiber Mach-Zehnder interferometer (MZI) on the interference observed, and thus on its potential applications in temperature sensing, has been investigated. The MZI was comprised of a tapered Ring Core Fiber (RCF), spliced between two single mode fibers (SMF). Since part of core mode from the SMF was converted into cladding modes in the RCF, due to the mismatch in the cores between the RCF and SMF, the residual power enters and then propagates along the center of the RCF (silica). The difference in phase between the radiation travelling along these different paths is separated by the HIRL to generate an interference effect. Compared with fiber interferometers based on core and cladding mode interference, the thin fiber HIRL is capable of separating the high order cladding modes and the silica core mode, under grazing incident conditions. Therefore, the optical path difference (OPD) and the sensitivity are both substantially improved over what is seen in conventional devices, showing their potential for interferometric temperature sensor applications. The optimum temperature sensitivity obtained was 186.6 pm/°C, which is ∼ 11.7 times higher than has been reported previously

A Practical System for Guaranteed Access in the Presence of DDoS Attacks and Flash Crowds

With the growing incidents of flash crowds and sophisticated DDoS attacks mimicking benign traffic, it becomes challenging to protect Internet-based services solely by differentiating attack traffic from legitimate traffic. While fair-sharing schemes are commonly suggested as a defense when differentiation is difficult, they alone may suffer from highly variable or even unbounded waiting times. We propose RainCheck Filter (RCF), a lightweight primitive that guarantees bounded waiting time for clients despite server flooding without keeping per-client state on the server. RCF achieves strong waiting time guarantees by prioritizing clients based on how long the clients have waited-as if the server maintained a queue in which the clients lined up waiting for service. To avoid keeping state for every incoming client request, the server sends to the client a raincheck, a timestamped cryptographic token that not only informs the client to retry later but also serves as a proof of the client's priority level within the virtual queue. We prove that every client complying with RCF can access the server in bounded time, even under a flash crowd incident or a DDoS attack. Our large-scale simulations confirm that RCF provides a small and predictable maximum waiting time while existing schemes cannot. To demonstrate its deployability, we implement RCF as a Python module such that web developers can protect a critical server resource by adding only three lines of code.Comment: 16 pages, a full technical report for 'A Practical System for Guaranteed Access in the Presence of DDoS Attacks and Flash Crowds' in IEEE International Conference on Network Protocols, 201

Rolling contact fatigue life of chromium ion plated 440C bearing steel

Rolling contact fatigue (RCF) test specimens of heat treated 440C bearing steel were chromium ion plated in thicknesses from 0.1 to 8.0 micron and tested in RCF tester using 700 ksi maximum Hertzian stress. Heavy coatings, greater than about 5 micron in thickness, peeled off or spalled readily, whereas thin coatings, less than 3 micron thick, were tenacious and did not come off. Furthermore, significant improvement in RCF life was obtained with thin chromium ion plated test specimens. The average increase in B10 life was 75% compared with unplated 440C. These preliminary results indicate that ion plating is a promising way to improve bearing life

An ultra scale-down analysis of the recovery by dead-end centrifugation of human cells for therapy.

An ultra scale-down method is described to determine the response of cells to recovery by dead-end (batch) centrifugation under commercially defined manufacturing conditions. The key variables studied are the cell suspension hold time prior to centrifugation, the relative centrifugal force (RCF), time of centrifugation, cell pellet resuspension velocities, and number of resuspension passes. The cell critical quality attributes studied are the cell membrane integrity and the presence of selected surface markers. Greater hold times and higher RCF values for longer spin times all led to the increased loss of cell membrane integrity. However, this loss was found to occur during intense cell resuspension rather than the preceding centrifugation stage. Controlled resuspension at low stress conditions below a possible critical stress point led to essentially complete cell recovery even at conditions of extreme centrifugation (e.g., RCF of 10000 g for 30 mins) and long (~2 h) holding times before centrifugation. The susceptibility to cell loss during resuspension under conditions of high stress depended on cell type and the age of cells before centrifugation and the level of matrix crosslinking within the cell pellet as determined by the presence of detachment enzymes or possibly the nature of the resuspension medium. Changes in cell surface markers were significant in some cases but to a lower extent than loss of cell membrane integrity. Biotechnol. Bioeng. 2015;112: 997-1011. © 2014 Wiley Periodicals, Inc

Residual stress field of HIPed silicon nitride rolling elements

The residual stress field of HIPed Si3N4 rolling elements were studied. Two kinds of HIPed Si3N4 ball blanks self-finished at different nominal lapping loads ranging from 1.3 to 10.87 kgf/ball and four kinds of commercially finished 1/2 in (12.7 mm) HIPed Si3N4 balls before, during and after RCF tests were investigated. The experimental results showed that in the finishing process of HIPed Si3N4 rolling elements. the surface and subsurface compressive residual stress induced is proportional to the lapping load applied. There was initially a high compressive residual stress layer on the HIPed Si3N4 ball blanks and this layer is mostly removed during the finishing process. During the rolling contact fatigue process of HIPed Si3N4 rolling elements, the residual stresses on the rolling track will change dramatically as RCF proceeds

Folate catabolites in spot urine as non-invasive biomarkers of folate status during habitual intake and folic acid supplementation.

Folate status, as reflected by red blood cell (RCF) and plasma folates (PF), is related to health and disease risk. Folate degradation products para-aminobenzoylglutamate (pABG) and para-acetamidobenzoylglutamate (apABG) in 24 hour urine have recently been shown to correlate with blood folate. Since blood sampling and collection of 24 hour urine are cumbersome, we investigated whether the determination of urinary folate catabolites in fasted spot urine is a suitable non-invasive biomarker for folate status in subjects before and during folic acid supplementation. Immediate effects of oral folic acid bolus intake on urinary folate catabolites were assessed in a short-term pre-study. In the main study we included 53 healthy men. Of these, 29 were selected for a 12 week folic acid supplementation (400 µg). Blood, 24 hour and spot urine were collected at baseline and after 6 and 12 weeks and PF, RCF, urinary apABG and pABG were determined. Intake of a 400 µg folic acid bolus resulted in immediate increase of urinary catabolites. In the main study pABG and apABG concentrations in spot urine correlated well with their excretion in 24 hour urine. In healthy men consuming habitual diet, pABG showed closer correlation with PF (rs = 0.676) and RCF (rs = 0.649) than apABG (rs = 0.264, ns and 0.543). Supplementation led to significantly increased folate in plasma and red cells as well as elevated urinary folate catabolites, while only pABG correlated significantly with PF (rs = 0.574) after 12 weeks. Quantification of folate catabolites in fasted spot urine seems suitable as a non-invasive alternative to blood or 24 hour urine analysis for evaluation of folate status in populations consuming habitual diet. In non-steady-state conditions (folic acid supplementation) correlations between folate marker (RCF, PF, urinary catabolites) decrease due to differing kinetics

Early handling and repeated cross-fostering have opposite effect on mouse emotionality

Early life events have a crucial role in programming the individual phenotype and exposure to traumatic experiences during infancy can increase later risk for a variety of neuropsychiatric conditions, including mood and anxiety disorders. Animal models of postnatal stress have been developed in rodents to explore molecular mechanisms responsible for the observed short and long lasting neurobiological effects of such manipulations. The main aim of this study was to compare the behavioral and hormonal phenotype of young and adult animals exposed to different postnatal treatments. Outbred mice were exposed to (i) the classical Handling protocol (H: 15 min-day of separation from the mother from day 1 to 14 of life) or to (ii) a Repeated Cross-Fostering protocol (RCF: adoption of litters from day 1 to 4 of life by different dams). Handled mice received more maternal care in infancy and showed the already described reduced emotionality at adulthood. Repeated cross fostered animals did not differ for maternal care received, but showed enhanced sensitivity to separation from the mother in infancy and altered respiratory response to 6% CO2 in breathing air in comparison with controls. Abnormal respiratory responses to hypercapnia are commonly found among humans with panic disorders (PD), and point to RCF-induced instability of the early environment as a valid developmental model for PD. The comparisons between short-and long-term effects of postnatal handling vs. RCF indicate that different types of early adversities are associated with different behavioral profiles, and evoke psychopathologies that can be distinguished according to the neurobiological systems disrupted by early-life manipulation