Multiple Antenna Techniques for Terahertz Nano-Bio Communication

Using higher frequency bands becomes an essential demand resulting from the explosive wireless traffic needs and the spectrum shortage of the currently used bands. This paper presents an overview on the terahertz technology and its application in the area of multi-input multi-output antenna system and in-vivo nano-communication. In addition, it presents a preliminary study on applying multiple input-single output (MISO) antenna technique to investigate the signal propagation and antenna diversity techniques inside the human skin tissues, which is represented by three layers: stratum corneum (SC), epidermis, and dermis layers, in the terahertz (THz) frequency range (0.8-1.2) THz. The spatial antenna diversity is investigated in this study to understand MISO system performance for two different in-vivo channels resulting from the signal propagation between two transmitting antennas, located at the dermis layer, and one receiving antenna, located at epidermis layer. Three techniques are investigated: selection combining (SC), equal-gain combing (EGC), and maximum-ratio combining (MRC). The initial study indicates that using multiple antenna technique with THz might be not useful for in-vivo nano-communication

THz Time Domain Characterization of Human Skin Tissue for Nano-Electromagnetic Communication

This paper presents an experimental investigation of excised human skin tissue material parameters by THz Time Domain Spectroscopy in the band 0.1-2.5 THz. The results are used to evaluate the channel path loss Nano-electromagnetic communication. Refractive index and absorption coefficient values are evaluated for dermis layer of the human skin. Results obtained illustrate the effect of hydrated tissue on channel parameters and provide the optimum distance, which can be utilized for effective communication inside the human skin

Emerging technologies for the non-invasive characterization of physical-mechanical properties of tablets

The density, porosity, breaking force, viscoelastic properties, and the presence or absence of any structural defects or irregularities are important physical-mechanical quality attributes of popular solid dosage forms like tablets. The irregularities associated with these attributes may influence the drug product functionality. Thus, an accurate and efficient characterization of these properties is critical for successful development and manufacturing of a robust tablets. These properties are mainly analyzed and monitored with traditional pharmacopeial and non-pharmacopeial methods. Such methods are associated with several challenges such as lack of spatial resolution, efficiency, or sample-sparing attributes. Recent advances in technology, design, instrumentation, and software have led to the emergence of newer techniques for non-invasive characterization of physical-mechanical properties of tablets. These techniques include near infrared spectroscopy, Raman spectroscopy, X-ray microtomography, nuclear magnetic resonance (NMR) imaging, terahertz pulsed imaging, laser-induced breakdown spectroscopy, and various acoustic- and thermal-based techniques. Such state-of-the-art techniques are currently applied at various stages of development and manufacturing of tablets at industrial scale. Each technique has specific advantages or challenges with respect to operational efficiency and cost, compared to traditional analytical methods. Currently, most of these techniques are used as secondary analytical tools to support the traditional methods in characterizing or monitoring tablet quality attributes. Therefore, further development in the instrumentation and software, and studies on the applications are necessary for their adoption in routine analysis and monitoring of tablet physical-mechanical properties

State-of-the-art terahertz sensing for food and water security – a comprehensive review

Background: Recently, there has been a dramatic change in the field of terahertz (THz) technology. The recent advancements in the THz radiation sector considering generation, manipulation and detection have brought revolution in this field, which enable the integration of THz sensing systems into real-world. The THz technology presents detection techniques and various issues, while providing significant opportunities for sensing food and water contamination detection. Scope and approach: Many researchers around the world have exploited the potential of invaluable new applications of THz sensing ranging from surveillance, healthcare and recently for food and water contamination detection. The microbial pollution in water and food is one the crucial issues with regard to the sanitary state for drinking water and daily consumption of food. To address this risk, the detection of microbial contamination is of utmost importance, since the consumption of insanitary or unhygienic food can lead to catastrophic illness. Key findings and conclusions: This paper presents a first-time review of the open literature covering the advances in the THz sensing for microbiological contamination of food and water, in addition to state-of-the-art in network architectures, applications and recent industrial developments. With unique superiority, the THz non-destructive detection technology in food inspection and water contamination detection is emerging as a new area of study. With the great progress, some important challenges and future research directions are presented within the field

THz Time-Domain Spectroscopy of Human Skin Tissue for In-Body Nanonetworks

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