Testing Prospects for Reliable Diatom Nanotechnology in Microgravity

The worldwide effort to grow nanotechnology, rather than use lithography, focuses on diatoms, single cell eukaryotic algae with ornate silica shells, which can be replaced by oxides and ceramics, or reduced to elemental silicon, to create complex nanostructures with compositions of industrial and electronics importance. Diatoms produce an enormous variety of structures, some of which are microtubule dependent and perhaps sensitive to microgravity. The NASA Single Loop for Cell Culture (SLCC) for culturing and observing microorganisms permits inexpensive, low labor in-space experiments. We propose to send up to the International Space Station diatom cultures of the three diatom species whose genomes are being sequenced, plus the giant diatoms of Antarctica (up to 2 mm diameter for a single cell) and the unique colonial diatom, Bacillaria paradoxa. Bacillaria cells move against each other in partial synchrony, like a sliding deck of cards, by a microfluidics mechanism. Will normal diatoms have aberrant pattern and shape or motility compared to ground controls? The generation time is typically one day, so that many generations may be examined from one flight. Rapid, directed evolution may be possible running the SLCC as a compustat. The shell shapes and patterns are preserved in hard silica, so that the progress of normal and aberrant morphogenesis may be followed by drying samples on a moving filter paper "diatom tape recorder". With a biodiversity of 100,000 distinct species, diatom nanotechnology may offer a compact and portable nanotechnology toolkit for exploration anywhere

A Multi-Level Framework for the Detection, Prioritization and Testing of Software Design Defects

Large-scale software systems exhibit high complexity and become difficult to maintain. In fact, it has been reported that software cost dedicated to maintenance and evolution activities is more than 80% of the total software costs. In particular, object-oriented software systems need to follow some traditional design principles such as data abstraction, encapsulation, and modularity. However, some of these non-functional requirements can be violated by developers for many reasons such as inexperience with object-oriented design principles, deadline stress. This high cost of maintenance activities could potentially be greatly reduced by providing automatic or semi-automatic solutions to increase system‟s comprehensibility, adaptability and extensibility to avoid bad-practices. The detection of refactoring opportunities focuses on the detection of bad smells, also called antipatterns, which have been recognized as the design situations that may cause software failures indirectly. The correction of one bad smell may influence other bad smells. Thus, the order of fixing bad smells is important to reduce the effort and maximize the refactoring benefits. However, very few studies addressed the problem of finding the optimal sequence in which the refactoring opportunities, such as bad smells, should be ordered. Few other studies tried to prioritize refactoring opportunities based on the types of bad smells to determine their severity. However, the correction of severe bad smells may require a high effort which should be optimized and the relationships between the different bad smells are not considered during the prioritization process. The main goal of this research is to help software engineers to refactor large-scale systems with a minimum effort and few interactions including the detection, management and testing of refactoring opportunities. We report the results of an empirical study with an implementation of our bi-level approach. The obtained results provide evidence to support the claim that our proposal is more efficient, on average, than existing techniques based on a benchmark of 9 open source systems and 1 industrial project. We have also evaluated the relevance and usefulness of the proposed bi-level framework for software engineers to improve the quality of their systems and support the detection of transformation errors by generating efficient test cases.Ph.D.Information Systems Engineering, College of Engineering and Computer ScienceUniversity of Michigan-Dearbornhttp://deepblue.lib.umich.edu/bitstream/2027.42/136075/1/Dilan_Sahin_Final Dissertation.pdfDescription of Dilan_Sahin_Final Dissertation.pdf : Dissertatio

Cassava brown streak virus disease: Past, present and future.

Cassava has been an important success story in Africa's developing agriculture over the past decade. The crop's inherei'lt capacity to cope with marginal growing conditions and unpredictable rainfall, coupled with determined efforts of a number of countries to move away from over-reliance on maize, have helped establish it as the continent's number one crop in terms of total fresh production. The hope provided by these gains is now threatened, however, by the devastating impact of the virus diseases, cassava mosaic and cassava brown streak. Both have been known for many years, but seem to be becoming increasingly damaging, and pose an ever greater threat to the livelihoods of the millions of Africans who depend on cassava as a food staple. Substantial effort has been directed towards understanding and managing cassava mosaic. By contrast, cassava brown streak disease (CBSD), which has a more limited distribution, and causes most severe damage in the coastal lowlands of Eastern and Southern Africa, has received little attention. In order to address this deficiency, an international workshop was convened at Mombasa, Kenya. This meeting brought together a diverse range of cassava stakeholders with the twin aims of reviewing current research into cassava brown streak and developing a plan to guide future research for development initiatives. The IS papers presented in these proceedings provide a useful and informative summary of the history and current status of CBSD, recent research initiatives and management options for the worst affected countries - Malawi, Tanzania, Kenya and Mozambique. Outputs of the research and on-farm working group sessions are also included. lt is anticipated that this information will serve both as a useful technical resource as well as an essential planning tool for scientists, development workers and others with an interest in the management of CBSD and the development of cassava in Africa

Faculty

Unprecedented recruiting success adds eight new faculty; Eisenberg, Schneider, \u2779, named to endowed professorships; Chinkin joins ranks of Affiliated Overseas Faculty; Heller, Hills, and Mann named full professors; Fox new director of Center for International and Comparative Law; CALC veteran Melissa Breger, \u2794, back on familiar turf; Legal Practice Program welcomes three new faculty members; Activities; Visiting faculty - reflections of the many sides of legal careers; U.S. Supreme Court draws on faculty members work; Faculty publications

Pest and disease incursions: risks, threats and management in Papua New Guinea; Papers presented at the 2nd Papua New Guinea Plant Protection Conference, Kokopo, East New Britain Province, 8–10 November 2004

Crop Production/Industries, Farm Management,