3,071 research outputs found

    A blockchain secured pharmaceutical distribution system to fight counterfeiting

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    Counterfeiting drugs has been a global concern for years. Considering the lack of transparency within the current pharmaceutical distribution system, research has shown that blockchain technology is a promising solution for an improved supply chain system. This study aims to explore the current solution proposals for distribution systems using blockchain technology. Based on a literature review on currently proposed solutions, it is identified that the secrecy of the data within the system and nodesā€™ reputation in decision making has not been considered. The proposed prototype uses a zero-knowledge proof protocol to ensure the integrity of the distributed data. It uses the Markov model to track each nodeā€™s ā€˜reputation scoreā€™ based on their interactions to predict the reliability of the nodes in consensus decision making. Analysis of the prototype demonstrates a reliable method in decision making, which concludes with overall improvements in the systemā€™s confidentiality, integrity, and availability. The result indicates that the decision protocol must be significantly considered in a reliable distribution system. It is recommended that the pharmaceutical distribution systems adopt a relevant protocol to design their blockchain solution. Continuous research is required further to increase performance and reliability within blockchain distribution systems

    Enhancing pharmaceutical packaging through a technology ecosystem to facilitate the reuse of medicines and reduce medicinal waste

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    The idea of reusing dispensed medicines is appealing to the general public provided its benefits are illustrated, its risks minimized, and the logistics resolved. For example, medicine reuse could help reduce medicinal waste, protect the environment and improve public health. However, the associated technologies and legislation facilitating medicine reuse are generally not available. The availability of suitable technologies could arguably help shape stakeholdersā€™ beliefs and in turn, uptake of a future medicine reuse scheme by tackling the risks and facilitating the practicalities. A literature survey is undertaken to lay down the groundwork for implementing technologies on and around pharmaceutical packaging in order to meet stakeholdersā€™ previously expressed misgivings about medicine reuse (ā€™stakeholder requirementsā€™), and propose a novel ecosystem for, in effect, reusing returned medicines. Methods: A structured literature search examining the application of existing technologies on pharmaceutical packaging to enable medicine reuse was conducted and presented as a narrative review. Results: Reviewed technologies are classified according to different stakeholdersā€™ requirements, and a novel ecosystem from a technology perspective is suggested as a solution to reusing medicines. Conclusion: Active sensing technologies applying to pharmaceutical packaging using printed electronics enlist medicines to be part of the Internet of Things network. Validating the quality and safety of returned medicines through this network seems to be the most effective way for reusing medicines and the correct application of technologies may be the key enabler

    Performance Analysis of Blockchain Platforms

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    Blockchain technologies have drawn massive attention to the world these past few years mostly because of the burst of cryptocurrencies like Bitcoin, Etherium, Ripple and many others. A Blockchain, also known as distributed ledger technology, has demonstrated huge potential in saving time and costs. This open-source technology which generates a decentralized public ledger of transactions is widely appreciated for ensuring a high level of privacy through encryption and thus sharing the transaction details only amongst the participants involved in the transactions. The Blockchain is used not only for cryptocurrency but also by various companies to meet their business ends, such as efficient management of supply chains and logistics. The rise and fall of numerous crypto-currencies based on blockchain technology have generated debate among tech-giants and regulatory bodies. There are various groups which are working on standardizing the blockchain technology. At the same time, numerous groups are actively working, developing and fine-tuning their own blockchain platforms. Platforms such as etherium, hyperledger, parity, etc. have their own pros and cons. This research is focused on the performance analysis of blockchain platforms which gives a comparative understanding of these platforms

    Benefits and guidelines for utilizing blockchain technology in pharmaceutical supply chains: case Bayer Pharmaceuticals

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    In this thesis, I explore how blockchain technology can improve pharmaceutical supply chain operations and discuss how the technology should be implemented. Furthermore, I study how the life science company Bayer's pharmaceutical division can utilize blockchain technology in its supply chain operations. I begin by defining the concepts of blockchain technology, smart contracts and pharmaceutical supply chain. Then I discuss the benefits and implementation in different sections: participating entities and information flow, contracts and payments, logistics, transparency and product security and blockchain infrastructure and governance. Both Bayer and the industry as a whole can benefit from blockchain technology. Blockchain enables for example efficient, safe and private transactions, product transparency and security and open information sharing without exposing trade secrets. For the first time a platform for all stakeholders can be developed that enables transacting information and value simultaneously
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