Graphical models for mediation analysis

Mediation analysis seeks to infer how much of the effect of an exposure on an outcome can be attributed to specific pathways via intermediate variables or mediators. This requires identification of so-called path-specific effects. These express how a change in exposure affects those intermediate variables (along certain pathways), and how the resulting changes in those variables in turn affect the outcome (along subsequent pathways). However, unlike identification of total effects, adjustment for confounding is insufficient for identification of path-specific effects because their magnitude is also determined by the extent to which individuals who experience large exposure effects on the mediator, tend to experience relatively small or large mediator effects on the outcome. This chapter therefore provides an accessible review of identification strategies under general nonparametric structural equation models (with possibly unmeasured variables), which rule out certain such dependencies. In particular, it is shown which path-specific effects can be identified under such models, and how this can be done

Nested Hierarchical Dirichlet Processes

We develop a nested hierarchical Dirichlet process (nHDP) for hierarchical topic modeling. The nHDP is a generalization of the nested Chinese restaurant process (nCRP) that allows each word to follow its own path to a topic node according to a document-specific distribution on a shared tree. This alleviates the rigid, single-path formulation of the nCRP, allowing a document to more easily express thematic borrowings as a random effect. We derive a stochastic variational inference algorithm for the model, in addition to a greedy subtree selection method for each document, which allows for efficient inference using massive collections of text documents. We demonstrate our algorithm on 1.8 million documents from The New York Times and 3.3 million documents from Wikipedia.Comment: To appear in IEEE Transactions on Pattern Analysis and Machine Intelligence, Special Issue on Bayesian Nonparametric

Long ranged singlet proximity effect in ferromagnetic nanowires

Recently a long ranged superconductor/ferromagnet (S/F) proximity effect has been reported in Co crystalline nanowires [1, Nature, 6 389 (2010)]. Since the authors of [1] take care to avoid the existence of magnetic domains, the triplet character of the long ranged proximity effect is improbable. Here we demonstrate that in the one-dimensional ballistic regime the standard singlet S/F proximity effect becomes long ranged. We provide an exact solution for the decay of the superconducting correlations near critical temperature ($T_{c}$) and for arbitrary impurities concentration. In particular we find a specific regime, between the diffusive and ballistic ones, where the decay length is simply the electronic mean-free path. Finally possible experiments which could permit to elucidate the nature of the observed long ranged proximity effect in Co nanowires are discussed.Comment: 4 page

Noncommutative Quantum Mechanics and rotating frames

We study the effect of noncommutativity of space on the physics of a quantum interferometer located in a rotating disk in a gauge field background. To this end, we develop a path-integral approach which allows defining an effective action from which relevant physical quantities can be computed as in the usual commutative case. For the specific case of a constant magnetic field, we are able to compute, exactly, the noncommutative Lagrangian and the associated shift on the interference pattern for any value of $\theta$.Comment: 17 pages, presentation improved, references added. To appear in Physical Review

The Fano regime of one-dot Aharonov-Bohm interferometers

We use the Landauer-B\"{u}ttiker formalism to study the mesoscopic Fano effect in Aharonov-Bohm rings with an embedded two-dimensional noninteracting dot. The magnetic field dependence of the dot levels leads to a global shift of the Fano lines which becomes important for small ring/dot area ratios. As the magnetic field is varied the Fano dips move periodically from one side of the peak to the other, as reported by Kobayashi {\it et al.} [Phys. Rev. Lett. {\bf 88}, 256806 (2002)]. We show that this effect appears due to a specific magnetic control of the difference between the phase of the single nonresonant path via the free arm of the ring and the global phase of all trajectories involving resonant tunnelings through the dot.Comment: To appear in Phys. Rev.

Path-Specific Effects

A cause may influence its effect via multiple paths. Paradigmatically (Hesslow, 1974), taking birth control pills both decreases one’s risk of thrombosis by preventing pregnancy and increases it by producing a blood chemical. Building on Pearl (2001), I explicate the notion of a path-specific effect. Roughly, a path-specific effect of C on E via path P is the degree to which a change in C would change E were they to be transmitted only via P. Facts about such effects may be gleaned from the structural equations commonly used to represent the causal relationships among variables. I contrast my analysis of the Hesslow case with those given by theorists of probabilistic causality, who mistakenly link it to issues of causal heterogeneity, token-causation and indeterminism. The reason probabilistic theories misdiagnose this case is that they pay inadequate attention to the structural relationships among variables