51,138 research outputs found
edge2vec: Representation learning using edge semantics for biomedical knowledge discovery
Representation learning provides new and powerful graph analytical approaches
and tools for the highly valued data science challenge of mining knowledge
graphs. Since previous graph analytical methods have mostly focused on
homogeneous graphs, an important current challenge is extending this
methodology for richly heterogeneous graphs and knowledge domains. The
biomedical sciences are such a domain, reflecting the complexity of biology,
with entities such as genes, proteins, drugs, diseases, and phenotypes, and
relationships such as gene co-expression, biochemical regulation, and
biomolecular inhibition or activation. Therefore, the semantics of edges and
nodes are critical for representation learning and knowledge discovery in real
world biomedical problems. In this paper, we propose the edge2vec model, which
represents graphs considering edge semantics. An edge-type transition matrix is
trained by an Expectation-Maximization approach, and a stochastic gradient
descent model is employed to learn node embedding on a heterogeneous graph via
the trained transition matrix. edge2vec is validated on three biomedical domain
tasks: biomedical entity classification, compound-gene bioactivity prediction,
and biomedical information retrieval. Results show that by considering
edge-types into node embedding learning in heterogeneous graphs,
\textbf{edge2vec}\ significantly outperforms state-of-the-art models on all
three tasks. We propose this method for its added value relative to existing
graph analytical methodology, and in the real world context of biomedical
knowledge discovery applicability.Comment: 10 page
Easing Embedding Learning by Comprehensive Transcription of Heterogeneous Information Networks
Heterogeneous information networks (HINs) are ubiquitous in real-world
applications. In the meantime, network embedding has emerged as a convenient
tool to mine and learn from networked data. As a result, it is of interest to
develop HIN embedding methods. However, the heterogeneity in HINs introduces
not only rich information but also potentially incompatible semantics, which
poses special challenges to embedding learning in HINs. With the intention to
preserve the rich yet potentially incompatible information in HIN embedding, we
propose to study the problem of comprehensive transcription of heterogeneous
information networks. The comprehensive transcription of HINs also provides an
easy-to-use approach to unleash the power of HINs, since it requires no
additional supervision, expertise, or feature engineering. To cope with the
challenges in the comprehensive transcription of HINs, we propose the HEER
algorithm, which embeds HINs via edge representations that are further coupled
with properly-learned heterogeneous metrics. To corroborate the efficacy of
HEER, we conducted experiments on two large-scale real-words datasets with an
edge reconstruction task and multiple case studies. Experiment results
demonstrate the effectiveness of the proposed HEER model and the utility of
edge representations and heterogeneous metrics. The code and data are available
at https://github.com/GentleZhu/HEER.Comment: 10 pages. In Proceedings of the 24th ACM SIGKDD International
Conference on Knowledge Discovery and Data Mining, London, United Kingdom,
ACM, 201
Predicting Social Links for New Users across Aligned Heterogeneous Social Networks
Online social networks have gained great success in recent years and many of
them involve multiple kinds of nodes and complex relationships. Among these
relationships, social links among users are of great importance. Many existing
link prediction methods focus on predicting social links that will appear in
the future among all users based upon a snapshot of the social network. In
real-world social networks, many new users are joining in the service every
day. Predicting links for new users are more important. Different from
conventional link prediction problems, link prediction for new users are more
challenging due to the following reasons: (1) differences in information
distributions between new users and the existing active users (i.e., old
users); (2) lack of information from the new users in the network. We propose a
link prediction method called SCAN-PS (Supervised Cross Aligned Networks link
prediction with Personalized Sampling), to solve the link prediction problem
for new users with information transferred from both the existing active users
in the target network and other source networks through aligned accounts. We
proposed a within-target-network personalized sampling method to process the
existing active users' information in order to accommodate the differences in
information distributions before the intra-network knowledge transfer. SCAN-PS
can also exploit information in other source networks, where the user accounts
are aligned with the target network. In this way, SCAN-PS could solve the cold
start problem when information of these new users is total absent in the target
network.Comment: 11 pages, 10 figures, 4 table
- …