18,235 research outputs found
Leakage-current properties of encapsulants
A theoretical modeling of leakage current in ethylene vinyl acetate (EVA) and polyvinyl butyral (PVB) modules is being developed and is described. The modeling effort derives mathematical relationships for the bulk and surface conductivites of EVA and PVB, the surface conductivities of glass and polymeric films, and the EVA and PVB pottants, all as functions of environmental parameters. Results from the modeling indicate that for glass/EVA, the glass surface controls the interfacial conductivity, although EVA bulk conductivity controls total leakage current. For PVB/glass, the interface conductivity controls leakage currents for relative humidity (RH) less than 40 to 50%, but PVB bulk conductivity controls leakage current above 50% RH
A new formulation of oral viscous budesonide in treating of paediatric eosinophilic oesophagitis: a pilot study
OBJECTIVES:
Oral viscous budesonide is a recent therapeutic option for eosinophilic oesophagitis (EoE) compared with dietary restriction and inhaled steroids. This single-centre, open-label, not blinded study aims to evaluate the efficacy and safety of a new, preprepared oral viscous budesonide suspension (PVB) in children and adolescents with EoE.
METHODS:
We treated 36 children with PVB (29 boys; median age 12 years) with EoE diagnosed according to European Society for Paediatric Gastroenterology Hepatology and Nutrition guidelines. Patients <150 and >150 cm height received 2 and 4 mg PVB daily, respectively, for 12 weeks. Upper gastrointestinal endoscopy was performed at baseline, after 12 weeks of therapy and 24 weeks after the end of therapy. Baseline and post-treatment scores were calculated for symptoms, endoscopy, and histology. Serum cortisol was performed at baseline, 12, and 36 weeks.
RESULTS:
At the end of PVB trial, endoscopy showed macroscopic remission in 32 patients (88.9%), whereas at histology median pre- and post-treatment peak eosinophil count/high power field (HPF) markedly decreased from 42.2 (range: 15-100) to 2.9 (range: 0-30); moreover, mean symptom and histology scores impressively improved compared with baseline (P < 0.01). At 24 weeks after the end of PVB therapy, endoscopy showed oesophageal relapse in 21 patients (58.3%), whereas 15 (41.7%) were still in remission. Seven children (19.4%) with positive multichannel intraluminal impedance-pH were treated also with proton pump inhibitors. No significant difference between pre-/post-treatment morning cortisol levels occurred.
CONCLUSIONS:
The new PVB suspension presented in the present study is effective and safe for treating children with proven EoE. Larger placebo-controlled clinical trials would provide more information about dosing, efficacy, and long-term safety of this formulation, specifically designed for the oesophagus
Partial-volume Bayesian classification of material mixtures in MR volume data using voxel histograms
The authors present a new algorithm for identifying the distribution of different material types in volumetric datasets such as those produced with magnetic resonance imaging (MRI) or computed tomography (CT). Because the authors allow for mixtures of materials and treat voxels as regions, their technique reduces errors that other classification techniques can create along boundaries between materials and is particularly useful for creating accurate geometric models and renderings from volume data. It also has the potential to make volume measurements more accurately and classifies noisy, low-resolution data well. There are two unusual aspects to the authors' approach. First, they assume that, due to partial-volume effects, or blurring, voxels can contain more than one material, e.g., both muscle and fat; the authors compute the relative proportion of each material in the voxels. Second, they incorporate information from neighboring voxels into the classification process by reconstructing a continuous function, ρ(x), from the samples and then looking at the distribution of values that ρ(x) takes on within the region of a voxel. This distribution of values is represented by a histogram taken over the region of the voxel; the mixture of materials that those values measure is identified within the voxel using a probabilistic Bayesian approach that matches the histogram by finding the mixture of materials within each voxel most likely to have created the histogram. The size of regions that the authors classify is chosen to match the sparing of the samples because the spacing is intrinsically related to the minimum feature size that the reconstructed continuous function can represent
The Pure Virtual Braid Group Is Quadratic
If an augmented algebra K over Q is filtered by powers of its augmentation
ideal I, the associated graded algebra grK need not in general be quadratic:
although it is generated in degree 1, its relations may not be generated by
homogeneous relations of degree 2. In this paper we give a sufficient criterion
(called the PVH Criterion) for grK to be quadratic. When K is the group algebra
of a group G, quadraticity is known to be equivalent to the existence of a (not
necessarily homomorphic) universal finite type invariant for G. Thus the PVH
Criterion also implies the existence of such a universal finite type invariant
for the group G. We apply the PVH Criterion to the group algebra of the pure
virtual braid group (also known as the quasi-triangular group), and show that
the corresponding associated graded algebra is quadratic, and hence that these
groups have a (not necessarily homomorphic) universal finite type invariant.Comment: 53 pages, 15 figures. Some clarifications added and inaccuracies
corrected, reflecting suggestions made by the referee of the published
version of the pape
Exotic Spin Order due to Orbital Fluctuations
We investigate the phase diagrams of the spin-orbital Kugel-Khomskii
model for increasing system dimensionality: from the square lattice monolayer,
via the bilayer to the cubic lattice. In each case we find strong competition
between different types of spin and orbital order, with entangled spin-orbital
phases at the crossover from antiferromagnetic to ferromagnetic correlations in
the intermediate regime of Hund's exchange. These phases have various types of
exotic spin order and are stabilized by effective interactions of longer range
which follow from enhanced spin-orbital fluctuations. We find that orbital
order is in general more robust and spin order melts first under increasing
temperature, as observed in several experiments for spin-orbital systems.Comment: 10 pages, 8 figure
Weak plaquette valence bond order in the honeycomb Heisenberg model
Using the density matrix renormalization group, we investigate the
Heisenberg model on the honeycomb lattice with first- () and
second-neighbor () interactions. We are able to study long open cylinders
with widths up to 12 lattice spacings. For near 0.3, we find an
apparently paramagnetic phase, bordered by an antiferromagnetic phase for
and by a valence bond crystal for . The
longest correlation length that we find in this intermediate phase is for
plaquette valence bond (PVB) order. This correlation length grows strongly with
cylinder circumference, indicating either quantum criticality or weak PVB
order.Comment: 9 pages, 15 figures, minor changes are made for publication in Phys.
Rev. Let
Polygonal vortex beams in quasi-frequency-degenerate states
We originally demonstrate the vortex beams with patterns of closed polygons
[namely polygonal vortex beams (PVBs)] generated by a
quasi-frequency-degenerate (QFD) Yb:CALGO laser resonator with astigmatic
transformation. The PVBs with peculiar patterns of triangular, square, and
parallelogram shapes carrying large orbital angular momentums (OAMs) are
theoretically investigated and experimentally obtained in the vicinity of the
SU(2) degenerate states of laser resonator. The PVBs in QFD states are compared
with the vortex beams with patterns of isolated spots arrays located on the
triangle-, square-, and parallelogram-shaped routes [namely
polygonalspots-array vortex beams (PSA-VBs)] under normal SU(2) degenerate
states. Beam profile shape of PVB or PSA-VB and OAM can be controlled by
adjusting the cavity length and the position of pump spot. The simulated and
experimental results validate the performance of our method to generate PVB,
which is of great potential for promoting novel technologies in particle
trapping and beam shaping
Impact of internal heating on the thermal evolution of neutron stars
The impact of various competing heating processes on the thermal evolution of
neutron stars is investigated. We show that internal heating leads to
significantly enhanced surface temperatures for pulsars of middle and old age.
The heating due to thermal creep of pinned vortices and due to outward motion
of proton vortices in the interior of the star leads to a better agreement with
the observed data in the case of enhanced cooling. The strong pinning models
are ruled out by a comparison with the cooling data on the old pulsars. For
millisecond pulsars, the heating due to thermal creep of pinned vortices and
chemical heating of the core have the largest impact on the surface
temperatures. The angular dependence of the heating rates require two
dimensional cooling simulations in general. Such a simulation is performed for
a selected case in order to check the applicability of one-dimensional codes
used in the past.Comment: 18 pages, to be published in A & A. Postscript and additional tables
at http://www.physik.uni-muenchen.de/sektion/suessmann/astro/cool/schaab.109
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