Effects of power law primordial magnetic field on big bang nucleosynthesis

Big bang nucleosynthesis (BBN) is affected by the energy density of a primordial magnetic field (PMF). For an easy derivation of constraints on models for PMF generations, we assume a PMF with a power law (PL) distribution in wave number defined with a field strength, a PL index, and maximum and minimum scales at a generation epoch. We then show a relation between PL-PMF parameters and the scale invariant (SI) strength of PMF for the first time. We perform a BBN calculation including PMF effects, and show abundances as a function of baryon to photon ratio $\eta$. The SI strength of the PMF is constrained from observational constraints on abundances of $^4$He and D. The minimum abundance of $^7$Li/H as a function of $\eta$ slightly moves to a higher $^7$Li/H value at a larger $\eta$ value when a PMF exists during BBN. We then discuss degeneracies between the PL-PMF parameters in the PMF effect. In addition, we assume a general case in which both the existence and the dissipation of PMF are possible. It is then found that an upper limit on the SI strength of the PMF can be derived from a constraint on $^4$He abundance, and that a lower limit on the allowed $^7$Li abundance is significantly higher than those observed in metal-poor stars.Comment: 15 pages, 5 figures, accepted for PRD 26 Oct 2012, published 10 December 201

Constraints on Primordial Magnetic Fields from Planck combined with the South Pole Telescope CMB B-mode polarization measurements

A primordial magnetic field (PMF) present before recombination can leave specific signatures on the cosmic microwave background (CMB) fluctuations. Of particular importance is its contribution to the B-mode polarization power spectrum. Indeed, vortical modes sourced by the PMF can dominate the B-mode power spectrum on small scales, as they survive damping up to a small fraction of the Silk length. Therefore, measurements of the B-mode polarization at high-$\ell$ , such as the one recently performed by the South Pole Telescope (SPT), have the potential to provide stringent constraints on the PMF. We use the publicly released SPT B-mode polarization spectrum, along with the temperature and polarization data from the Planck satellite, to derive constraints on the magnitude, the spectral index and the energy scale at which the PMF was generated. We find that, while Planck data constrains the magnetic amplitude to $B_{1 \, \text{Mpc}} < 3.3$ nG at 95\% confidence level (CL), the SPT measurement improves the constraint to $B_{1 \, \text{Mpc}} < 1.5$ nG. The magnetic spectral index, $n_B$, and the time of the generation of the PMF are unconstrained. For a nearly scale-invariant PMF, predicted by simplest inflationary magnetogenesis models, the bound from Planck+SPT is $B_{1 \, \text{Mpc}} < 1.2$ nG at 95% CL. For PMF with $n_B=2$, expected for fields generated in post-inflationary phase transitions, the 95% CL bound is $B_{1 \, \text{Mpc}} < 0.002$ nG, corresponding to the magnetic fraction of the radiation density $\Omega_{B\gamma} < 10^{-3}$ or the effective field $B_{\rm eff} < 100$ nG. The patches for the Boltzmann code CAMB and the Markov Chain Monte Carlo engine CosmoMC, incorporating the PMF effects on CMB, are made publicly available.Comment: 12 pages, 9 figures, 4 table

Optimization-Based Peptide Mass Fingerprinting for Protein Mixture Identification

*Motivation:* In current proteome research, peptide sequencing is probably the most widely used method for protein mixture identification. However, this peptide-centric method has its own disadvantages such as the immense volume of tandem Mass Spectrometry (MS) data for sequencing peptides. With the fast development of technology, it is possible to investigate other alternative techniques. Peptide Mass Fingerprinting (PMF) has been widely used to identify single purified proteins for more than 15 years. Unfortunately, this technique is less accurate than peptide sequencing method and cannot handle protein mixtures, which hampers the widespread use of PMF technique. If we can remove these limitations, PMF will become a useful tool in protein mixture identification. &#xd;&#xa;*Results:* We first formulate the problem of PMF protein mixture identification as an optimization problem. Then, we show that the use of some simple heuristics enables us to find good solutions. As a result, we obtain much better identification results than previous methods. Moreover, the result on real MS data can be comparable with that of the peptide sequencing method. Through a comprehensive simulation study, we identify a set of limiting factors that hinder the performance of PMF method in protein mixtures. We argue that it is feasible to remove these limitations and PMF can be a powerful tool in the analysis of protein mixtures

Shotguns vs Lasers: Identifying barriers and facilitators to scaling-up plant molecular farming for high-value health products.

Plant molecular farming (PMF) is a convenient and cost-effective way to produce high-value recombinant proteins that can be used in the production of a range of health products, from pharmaceutical therapeutics to cosmetic products. New plant breeding techniques (NPBTs) provide a means to enhance PMF systems more quickly and with greater precision than ever before. However, the feasibility, regulatory standing and social acceptability of both PMF and NPBTs are in question. This paper explores the perceptions of key stakeholders on two European Union (EU) Horizon 2020 programmes-Pharma-Factory and Newcotiana-towards the barriers and facilitators of PMF and NPBTs in Europe. One-on-one qualitative interviews were undertaken with N = 20 individuals involved in one or both of the two projects at 16 institutions in seven countries (Belgium, France, Germany, Italy, Israel, Spain and the UK). The findings indicate that the current EU regulatory environment and the perception of the public towards biotechnology are seen as the main barriers to scaling-up PMF and NPBTs. Competition from existing systems and the lack of plant-specific regulations likewise present challenges for PMF developing beyond its current niche. However, respondents felt that the communication of the benefits and purpose of NPBT PMF could provide a platform for improving the social acceptance of genetic modification. The importance of the media in this process was highlighted. This article also uses the multi-level perspective to explore the ways in which NPBTs are being legitimated by interested parties and the systemic factors that have shaped and are continuing to shape the development of PMF in Europe

The Search for a Primordial Magnetic Field

Magnetic fields appear wherever plasma and currents can be found. As such, they thread through all scales in Nature. It is natural, therefore, to suppose that magnetic fields might have been formed within the high temperature environments of the big bang. Such a primordial magnetic field (PMF) would be expected to arise from and/or influence a variety of cosmological phenomena such as inflation, cosmic phase transitions, big bang nucleosynthesis, the cosmic microwave background (CMB) temperature and polarization anisotropies, the cosmic gravity wave background, and the formation of large-scale structure. In this review, we summarize the development of theoretical models for analyzing the observational consequences of a PMF. We also summarize the current state of the art in the search for observational evidence of a PMF. In particular we review the framework needed to calculate the effects of a PMF power spectrum on the CMB and the development of large scale structure. We summarize the current constraints on the PMF amplitude $B_\lambda$ and the power spectral index $n_B$ and discuss prospects for better determining these quantities in the near future.Comment: 40 pages, 13 figures, Accepted for Physics Reports 23 Feb 2012. Available online 3 March 2012. In press, corrected proo