In vitro and in vivo leishmanicidal studies of Peperomia galioides (Piperaceae)

Petroleum ether and methylene chloride extracts of #Peperomia galioides and three phenylated diphenols, grifolic acid, grifolin and piperogalin exhibited in vitro antileishmanial activity. During the course of infection of BALB/c mice with #Leishmania amazonensis, the treatments with each of these compounds did not influence the progression of the disease. (Résumé d'auteur