Targeting inflammation to reduce cardiovascular disease risk

This joint themed section of the British Journal of Pharmacology and the British Journal of Clinical Pharmacology stems from a joint British Pharmacological Society – Italian Society of Pharmacology symposium held at the 37th National Congress of the Italian Society of Pharmacology in Naples (Italy) from 27 to 30 October 2015

English Language Acculturation and Academic Achievement Among Junior Year Nursing Students

Efforts to alleviate the current nursing shortage have focused on recruitment and retention of diverse nursing students. Language acculturation has been identified in the literature as one predictor of academic achievement (Salamonson et al, 2008) PURPOSE: This study examined the relationship between pathophysiology and pharmacology grades and scores on the English Language Acculturation Scale (ELAS) survey for junior-level nursing students (N = 65). The relationship between years living in the United States (U.S.) and pathophysiology and pharmacology grades was examined also. RESULTS: ELAS scores ranged from 7-25, with a mean of22 (SD = 4.27). No statistically significant correlation was found between pathophysiology or pharmacology grades and ELAS score. A weak correlation was identified between length of time lived in the U.S. and pathophysiology grades (r =.260, p \u3c .05) and pharmacology grades (r = .288, p \u3c .05). For this sample, success in pharmacology and pathophysiology coursework paralleled linguistic competence

Pharmacology

The popular trope which depicts the origin of life on earth as emerging from a ?chemical soup? continues to have an enduring hold over the imagination. Of course, whether this ?soup? was a prebiotic puddle on the surface of this third rock from the Sun, originally ?canned?, superheated and pressurised in one of its internal faults, or a kind of extraterrestrial material reheated in some way after having reached the early Earth from elsewhere in universe, may not be known for sure. Nevertheless, advances in sciences such as paleogenomics and paleohistology have shown us that at least a part of the story of the origin of life can be traced in each and every cell of our living bodies

A Multi-Level Analysis of World Scientific Output in Pharmacology

The purpose of this chapter is to analyse international research in “pharmacology, toxicology and pharmaceutics” (hereafter pharmacology) on the basis of the scientific papers listed in the Scopus multidisciplinary database. This primary objective is reached by answering the following questions (in the section on results). What weight does the subject area “pharmacology, toxicology and pharmaceutics” carry in world-wide science? What is the percentage contribution made by the various regions of the world to the subject area “pharmacology, toxicology and pharmaceutics”? Can certain regions be identified as leaders on that basis, as in other scientific contexts? Are emerging countries present in the field? Do the most productive countries also publish the largest number of journals? What features characterise the scientific output of companies that publish pharmacological papers

Systems Pharmacology

The slides are from a presentation given by Professor Ravi Iyengar from Mount Sinai School of Medicine at the Drug Forum Meeting #9 that took place in Washington, DC on February 20-21, 2008. The slides describe two projects: one that was published last year, and the other unpublished. These projects used network analysis to explore the relationships between FDA approved drugs and a human protein-protein interaction network

Clinical Pharmacology & Therapeutics: Past, Present, and Future.

Clinical Pharmacology & Therapeutics (CPT), the definitive and timely source for advances in human therapeutics, transcends the drug discovery, development, regulation, and utilization continuum to catalyze, evolve, and disseminate discipline-transformative knowledge. Prioritized themes and multidisciplinary content drive the science and practice of clinical pharmacology, offering a trusted point of reference. An authoritative herald across global communities, CPT is a timeless information vehicle at the vanguard of discovery, translation, and application ushering therapeutic innovation into modern healthcare

Personalized medicine : the impact on chemistry

An effective strategy for personalized medicine requires a major conceptual change in the development and application of therapeutics. In this article, we argue that further advances in this field should be made with reference to another conceptual shift, that of network pharmacology. We examine the intersection of personalized medicine and network pharmacology to identify strategies for the development of personalized therapies that are fully informed by network pharmacology concepts. This provides a framework for discussion of the impact personalized medicine will have on chemistry in terms of drug discovery, formulation and delivery, the adaptations and changes in ideology required and the contribution chemistry is already making. New ways of conceptualizing chemistry’s relationship with medicine will lead to new approaches to drug discovery and hold promise of delivering safer and more effective therapies