Usefulness of a commercial enzyme-linked immunosorbent assay kit for Candida mannan antigen for detecting Candida in oral rinse solutions

ArticleORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY. 107(4):531-534 (2009)journal articl

Immunohistochemical Localization of REG Ia Protein in Salivary Gland Tumors

The regenerating gene( Reg) Ia protein has a trophic effect on gastric epithelial cells, and its overexpressionis reported in gastrointestinal cancers. The salivary gland is a component of the digestive system, andtherefore, REG Ia protein may play some role in the pathophysiology of salivary gland tumors. In the presentstudy, we determined the immunohistochemical localization of REG Ia protein in salivary gland tumorsand moreover investigated its relationship to clinicopathological features. Twenty-eight patients with salivarygland tumor were enrolled. The specimens resected by surgery from those patients were examinedusing immunohistochemistry for REG Ia protein and Ki67. Five of the 16 pleomorphic adenomas (31.3%)were positive for REG Ia protein. Regarding salivary gland carcinomas, four of five mucoepidermoid carcinomas(80%), three of five adenoid cystic carcinomas (60%), one of two polymorphous low-grade adenocarcinomas(50%) were also positive for REG Ia protein. However, no relationships were found betweenREG Ia protein expression and clinicopathological features. Regarding the Ki67 expression, strong signalwas observed in the tumor cells of patients with salivary gland adenoma as well as carcinoma. REG Ia proteinis expressed not only in adenocarcinoma but also precancerous adenoma cells proliferating actively,suggesting that REG Ia protein may play a role at least in part in the development of salivary gland tumors

Oral biopsies in a Portuguese population : a 20-year clinicopathological study in a university clinic

Performing a biopsy is very important in oral medicine and the anatomopathological examination is fundamental to obtain or to confirm the diagnosis in oral and maxillofacial pathology. The purpose of this study is to analyse the frequency and characteris

SIPMO 2019

The biennial Congress of the Italian Society of Oral Pathology and Medicine (SIPMO) is an International meeting dedicated to the growing diagnostic challenges in the oral pathology and medicine field. The III International and XV National edition will be a chance to discuss clinical conditions which are unusual, rare, or difficult to define. Many consolidated national and international research groups will be involved in the debate and discussion through special guest lecturers, academic dissertations, single clinical case presentations, posters, and degree thesis discussions. The SIPMO Congress took place from the 17th to the 19th of October 2019 in Bari (Italy), and the enclosed copy of Proceedings is a non-exhaustive collection of abstracts from the SIPMO 2019 contributions

85th Birthady Prof. dr. Milutin Dobrenić

Profesor dr. sc. Milutin Dobrenić, dugogodišnji predstojnik Zavoda za oralnu patologiju Stomatološkog fakulteta u Zagrebu i pročelnik Odjela za bolesti usta Stomatološke klinike KBC-a Zagreb, slavi 15. svibnja ove godine 85. rođendan. Doktor Filozofskih i Medicinskih znanosti radi u stomatološkoj struci od godine 1948. Od školske poliklinike u Zagrebu, kao stručni suradnik i asistent na Stomatološkom fakultetu u Zagrebu, i kao docent na Zavodu za dentalnu patologiju. Od godine 1962. - 1983., tj. do umirovljenja, kao izvanredni i redovni profesor, vodi nastavu iz Oralne patologije, kao predstojnik toga zavoda.On the 15th May 2002 Prof. Milutin Dobrenić will celebrate his 85th birthday. Prof. Dobrenić was for many years Head of the Department of Oral Pathology at the School of Dental Medicine in Zagreb and Director of the Department of Oral Diseases in the Dental Clinic at the University Hospital Centre in Zagreb. He is a Doctor of Philosophy and Medical Sciences. He started work in the dental profession in 1948, in the School Polyclinic in Zagreb as a professional collaborator and Assistant at the School of Dental Medicine in Zagreb, and as lecturer in the Department of Dental Pathology. As Head of the Department, he taught Oral Pathology as an Associate and Full Professor from 1962 to 1983, up until his retirement. He was the founder of contemporary clinical disciplines in Oral Pathology, which he headed up until his retirement

A flipped classroom approach to teaching oral pathology using virtual microscopy - the Glasgow experience

This paper describes a student-centred, integrated teaching model in which oral pathology and oral medicine staff members jointly deliver tutorials in a combined online and face-to-face format. Students are provided with clinical and histopathological information, which they must review and use to answer questions via a Virtual Learning Environment before the tutorial takes place. By reviewing the students’ answers online before the teaching session, staff can focus the tutorial itself on resolving knowledge gaps and afterwards post a set of gold standard answers online for students to reflect upon. CPD/Clinical Relevance: This article illustrates a combination of teaching methods and modern technologies which integrate clinical with laboratory sciences and enhance the access of students to histopathological materials without the need for access to a traditional microscopy facility

Mucoceles of the oral cavity : a large case series (1994-2008) and a literature review

Objectives: Evaluating data of patients affected by oral mucoceles, examined at the Unit of Oral Medicine and Pathology of the University of Milan between January 1994 and December 2008. Study Design: Concise review on oral mucoceles and analysis of the clinical files of patients who underwent excisional biopsy (patient age, medical history, diagnosis, date and site of the biopsy, histopathological diagnosis and recurrences if any). Results: During the period June 1994-December 2008, 158 mucoceles were observed (93 males and 65 females), with the most frequent site being the lower lip (53%) (p=0.001 by Fisher?s test). The mean age of the patients was 31.9 years, with a peak of occurrence in the first four decades of life (75%). Conclusions: Mucoceles are lesions commonly seen in an oral medicine service, mainly affecting young people and lower lips

Autofluorescence and diagnostic accuracy of lesions of oral mucosa: a pilot study

The purpose of this study was to determine the accuracy of autofluorescence techniques for diagnosing oral mucosa lesions, using as reference pattern for comparison the visual diagnosis made by a clinical specialist. A pilot study was conducted with 60 patients divided in a control group without mucosal pathology and a study group with known clinical history for mucosal pathology. Both groups were examined by an oral medicine specialist and by a general dentist who used VELscope(r) system, which applies tissue fluorescence visualization to identify oral mucosal abnormalities. Using the VELscope(r) system, the general dentist made overdiagnosis in two cases and underdiagnosis in one case. The sensitivity and specificity for the oral medicine specialist were 1 (95% CI: 0.884 to 1). For the general dentist, the sensitivity did not improve significantly with the use of VELscope(r) system [0.53 (95% CI: 0.343 to 0.717) versus 0.49 (95% CI: 0.406 to 0.773)] and the specificity was 0.80 (95% CI: 0.614 to 0.923). A limitation of the study is the small sample size, which does not fully represent a population and extrapolation of the data should be done carefully. Based on the obtained results, no clinical benefits were obtained using this VELscope(r) system