4,177 research outputs found
UMSL Bulletin 2023-2024
The 2023-2024 Bulletin and Course Catalog for the University of Missouri St. Louis.https://irl.umsl.edu/bulletin/1088/thumbnail.jp
Study of neural circuits using multielectrode arrays in movement disorders
Treballs Finals de Grau d'Enginyeria Biomèdica. Facultat de Medicina i Ciències de la Salut. Universitat de Barcelona. Curs: 2022-2023. Tutor/Director: Rodríguez Allué, Manuel JoséNeurodegenerative movement-related disorders are characterized by a progressive degeneration and loss of neurons, which lead to motor control impairment. Although the precise mechanisms underlying these conditions are still unknown, an increasing number of studies point towards the analysis of neural networks and functional connectivity to unravel novel insights. The main objective of this work is to understand cellular mechanisms related to dysregulated motor control symptoms in movement disorders, such as Chorea-Acanthocytosis (ChAc), by employing multielectrode arrays to analyze the electrical activity of neuronal networks in mouse models. We found no notable differences in cell viability between neurons with and without VPS13A knockdown, that is the only gene known to be implicated in the disease, suggesting that the absence of VPS13A in neurons may be partially compensated by other proteins. The MEA setup used to capture the electrical activity from neuron primary cultures is described in detail, pointing out its specific characteristics. At last, we present the alternative backup approach implemented to overcome the challenges faced during the research process and to explore the advanced algorithms for signal processing and analysis.
In this report, we present a thorough account of the conception and implementation of our research, outlining the multiple limitations that have been encountered all along the course of the project. We provide a detailed analysis on the project’s economical and technical feasibility, as well as a comprehensive overview of the ethical and legal aspects considered during the execution
Reshaping Higher Education for a Post-COVID-19 World: Lessons Learned and Moving Forward
No abstract available
Making Connections: A Handbook for Effective Formal Mentoring Programs in Academia
This book, Making Connections: A Handbook for Effective Formal Mentoring Programs in Academia, makes a unique and needed contribution to the mentoring field as it focuses solely on mentoring in academia. This handbook is a collaborative institutional effort between Utah State University’s (USU) Empowering Teaching Open Access Book Series and the Mentoring Institute at the University of New Mexico (UNM). This book is available through (a) an e-book through Pressbooks, (b) a downloadable PDF version on USU’s Open Access Book Series website), and (c) a print version available for purchase on the USU Empower Teaching Open Access page, and on Amazon
Interdisciplinarity in the Scholarly Life Cycle
This open access book illustrates how interdisciplinary research develops over the lifetime of a scholar: not in a single project, but as an attitude that trickles down, or spirals up, into research. This book presents how interdisciplinary work has inspired shifts in how the contributors read, value concepts, critically combine methods, cope with knowledge hierarchies, write in style, and collaborate. Drawing on extensive examples from the humanities and social sciences, the editors and chapter authors show how they started, tried to open up, dealt with inconsistencies, had to adapt, and ultimately learned and grew as researchers. The book offers valuable insights into the conditions and complexities present for interdisciplinary research to be successful in an academic setting. This is an open access book
The mad manifesto
The “mad manifesto” project is a multidisciplinary mediated investigation into the circumstances by which mad (mentally ill, neurodivergent) or disabled (disclosed, undisclosed) students faced far more precarious circumstances with inadequate support models while attending North American universities during the pandemic teaching era (2020-2023).
Using a combination of “emergency remote teaching” archival materials such as national student datasets, universal design for learning (UDL) training models, digital classroom teaching experiments, university budgetary releases, educational technology coursewares, and lived experience expertise, this dissertation carefully retells the story of “accessibility” as it transpired in disabling classroom containers trapped within intentionally underprepared crisis superstructures. Using rhetorical models derived from critical disability studies, mad studies, social work practice, and health humanities, it then suggests radically collaborative UDL teaching practices that may better pre-empt the dynamic needs of dis/abled students whose needs remain direly underserviced.
The manifesto leaves the reader with discrete calls to action that foster more critical performances of intersectionally inclusive UDL classrooms for North American mad students, which it calls “mad-positive” facilitation techniques:
1. Seek to untie the bond that regards the digital divide and access as synonyms.
2. UDL practice requires an environment shift that prioritizes change potential.
3. Advocate against the usage of UDL as a for-all keystone of accessibility.
4. Refuse or reduce the use of technologies whose primary mandate is dataveillance.
5. Remind students and allies that university space is a non-neutral affective container.
6. Operationalize the tracking of student suicides on your home campus.
7. Seek out physical & affectual ways that your campus is harming social capital potential.
8. Revise policies and practices that are ability-adjacent imaginings of access.
9. Eliminate sanist and neuroscientific languaging from how you speak about students.
10. Vigilantly interrogate how “normal” and “belong” are socially constructed.
11. Treat lived experience expertise as a gift, not a resource to mine and to spend.
12. Create non-psychiatric routes of receiving accommodation requests in your classroom.
13. Seek out uncomfortable stories of mad exclusion and consider carceral logic’s role in it.
14. Center madness in inclusive methodologies designed to explicitly resist carceral logics.
15. Create counteraffectual classrooms that anticipate and interrupt kairotic spatial power.
16. Strive to refuse comfort and immediate intelligibility as mandatory classroom presences.
17. Create pathways that empower cozy space understandings of classroom practice.
18. Vector students wherever possible as dynamic ability constellations in assessment
Integration of BIM in Building Sustainability Assessment methods
Tese de doutoramento em Sustentabilidade do Ambiente ConstruídoThe Architecture, Engineering and Construction (AEC) industry is highly responsible for several environmental
impacts and worldwide authorities and societies are increasingly looking for more sustainable buildings.
Given the ambitious targets of climate neutrality and decarbonisation, there is an urgent need to develop
specific strategies to act in the building sector, as it has been recognised as a key industry to reverse
environmental impacts. Among the existing tools, Building Sustainability Assessment (BSA) methods stand
out as a pathway to evaluate and promote the integration of sustainability principles in buildings. However,
such methods often require multi-disciplinary information about the building and significant resources such
as time, money, and human labour. Consequently, and in the absence of mandatory legislation, BSA is
usually neglected or applied in project later stages just to provide a sustainable evaluation of the building.
With the deployment of Building Information Modelling (BIM), the opportunity for BSA to adopt and benefit
from BIM functionalities arises. Currently, BIM has not been used comprehensively in the evaluation process
of BSA but the potential for process automation and simplification are well known. To effectively integrate
BSA into BIM environment, this research aims to develop a BIM integration framework for the Portuguese
residential BSA method SBToolPT-H. Moreover, such framework will be materialized by the creation of an enduser
BIM-based application – SBToolBIM – which will act as a decision support tool regarding building
sustainability for the project's early stages. SBToolBIM will automate and accelerate the assessment of SBToolPTH
by reflecting its criteria through computable rules. Results show the attractiveness of SBToolBIM, as well as
the possibility to have real-time feedback about the building sustainability level in early project stages, allowing
for the introduction and comparison of different sustainability measures with few resources. SBToolBIM has
established a novel and common approach which can be used as a systematic framework to apply BIM in
other BSA schemes, representing a pathway to reduce the building sector impacts and provide valuable
contributes to reach worldwide climate neutrality and decarbonisation targets.A indústria da Arquitetura, Engenharia e Construção (AEC) é responsável por diversos impactes ambientais,
levando as autoridades e sociedades mundiais à procura por edifícios mais sustentáveis. Perante os
ambiciosos objetivos da neutralidade climática e descarbonização, surge a necessidade de desenvolver
estratégias específicas para o setor dos edifícios, dado ser uma indústria chave para a reversão dos referidos
impactes. Entre as ferramentas existentes, destacam-se os métodos da avaliação da sustentabilidade de
edifícios (BSA, do inglês Building Sustainability Assessment) como forma de avaliar e promover a integração
de medidas sustentáveis. No entanto, a sua utilização requer informações multidisciplinares do edifício, bem
como recursos significativos, tais como tempo, custos e mão de obra. Consequentemente e na ausência de
legislação obrigatória, os BSA são geralmente negligenciados ou aplicados em fases finais de projeto, apenas
para identificar o nível de sustentabilidade do edifício. Com a implementação do Building Information
Modeling (BIM), surge a oportunidade dos BSA adotarem e beneficiarem das suas funcionalidades.
Atualmente, o BIM ainda não é integralmente utilizado no processo de avaliação dos BSA, mas as suas
potencialidades para automação e simplificação do processo já foram reconhecidas. De modo a integrar os
BSA em ambiente BIM, este trabalho visa desenvolver uma estrutura de integração BIM para o método BSA
residencial português SBToolPT-H. A estrutura será materializada através da criação de uma aplicação BIM –
SBToolBIM – que irá atuar como uma ferramenta de apoio à decisão em fases iniciais de projeto. O SBToolBIM
irá automatizar e acelerar os processos de avaliação da sustentabilidade através do SBToolPT-H, refletindo os
seus critérios através de regras computacionais. Os resultados demonstram a utilidade do SBToolBIM, bem
como a possibilidade de fornecer feedback em tempo real sobre o nível de sustentabilidade do edifício nas
fases iniciais de projeto, permitindo a introdução e a comparação de diferentes medidas de sustentabilidade,
utilizando poucos recursos. O SBToolBIM estabelece uma nova abordagem sistemática para aplicação do BIM
noutros métodos BSA, representando um caminho para a redução dos impactes do setor e dando valiosas
contribuições para alcançar as metas de neutralidade climática e descarbonização.SBToolBIM research was funded by the Portuguese Foundation for Science and Technology (FCT), grant
number SFRH/BD/145735/2019
Architecture and Advanced Electronics Pathways Toward Highly Adaptive Energy- Efficient Computing
With the explosion of the number of compute nodes, the bottleneck of future computing systems lies in the network architecture connecting the nodes. Addressing the bottleneck requires replacing current backplane-based network topologies. We propose to revolutionize computing electronics by realizing embedded optical waveguides for onboard networking and wireless chip-to-chip links at 200-GHz carrier frequency connecting neighboring boards in a rack. The control of novel rate-adaptive optical and mm-wave transceivers needs tight interlinking with the system software for runtime resource management
2023-2024 Undergraduate Catalog
2023-2024 undergraduate catalog for Morehead State University
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