Exercise Does Not Effect Context-dependent Episodic Memory

Memory has been shown to be strongly associated with the context in which it is encoded, suggesting that the context is central to the memory itself. However, the effect of exercise on context dependent object recognition is not fully known. We then set out to investigate the effect of exercise on context dependent object recognition. In Experiment 1 we showed that a context change reduced object recognition memory but did not significantly disrupt object recognition. In Experiment 2 we assessed whether exercise would the mitigate the effect of context change. We showed that exercise does not significantly improve object recognition nor did it mitigate the effect of context change on object recognition. These results suggest that a discrete context change can significantly disrupt retrieval of object recognition memory. Our results do not agree with the body of literature related to this topic, so further inquisition into these effects should be undertaken to confirm or refute the impact of exercise on contextual object recognition

The self-reference effect on memory in early childhood

The self-reference effect in memory is the advantage for information encoded about self, relative to other people. The early development of this effect was explored here using a concrete encoding paradigm. Trials comprised presentation of a self- or other-image paired with a concrete object. In Study 1, 4- to 6-year-old children (N = 53) were asked in each trial whether the child pictured would like the object. Recognition memory showed an advantage for self-paired objects. Study 2 (N = 55) replicated this finding in source memory. In Study 3 (N = 56), participants simply indicated object location. Again, recognition and source memory showed an advantage for self-paired items. These findings are discussed with reference to mechanisms that ensure information of potential self-relevance is reliably encoded

A correspondence-based neural mechanism for position invariant feature processing

Poster presentation: Introduction We here focus on constructing a hierarchical neural system for position-invariant recognition, which is one of the most fundamental invariant recognition achieved in visual processing [1,2]. The invariant recognition have been hypothesized to be done by matching a sensory image of a particular object stimulated on the retina to the most suitable representation stored in memory of the higher visual cortical area. Here arises a general problem: In such a visual processing, the position of the object image on the retina must be initially uncertain. Furthermore, the retinal activities possessing sensory information are being far from the ones in the higher area with a loss of the sensory object information. Nevertheless, with such recognition ambiguity, the particular object can effortlessly and easily be recognized. Our aim in this work is an attempt to resolve such a general recognition problem. ..

NMDA receptor plasticity in the perirhinal and prefrontal cortices is crucial for the acquisition of long-term object-in-place associative memory

A key process for recognition memory is the formation of associations between an object and the place in which it was encountered, a process that has been shown to require the perirhinal (PRH) and medial prefrontal (mPFC) cortices. Here we demonstrate, for the first time, the importance of glutamatergic neurotransmission, within the PRH and mPFC, for object-in-place associative recognition memory. Unilateral blockade of AMPA receptors (by CNQX) in the PRH and mPFC in opposite hemispheres impaired an object-in-place task in rats, confirming that these cortical regions operate within a neural network for object-in-place recognition memory. Intra-mPFC infusions of AP5 (NMDA receptor antagonist) impaired short-term memory and the acquisition of long-term memory, but had no effect on retrieval. AP5 infusions into the PRH disrupted acquisition of long-term memory, but not short-term memory or retrieval. Significantly, crossed AP5 infusions into both the PRH and mPFC disrupted acquisition of long-term memory but were without effect on short-term memory. Finally a unilateral infusion of the selective kainate (GLU(K5)) receptor antagonist UBP302 [(S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione] into the PRH combined with a unilateral infusion of AP5 into the contralateral mPFC significantly impaired short-term object-in-place associative memory. These data show that the PRH and mPFC make distinct contributions to object-in-place associative memory and that the encoding of long-term but not short-term memory requires concurrent NMDA receptor activation in both cortical regions. In contrast, short-term object-in-place memory appears to be dependent on kainate receptor activation in the PRH and NMDA receptor activation in the mPFC.A key process for recognition memory is the formation of associations between an object and the place in which it was encountered, a process that has been shown to require the perirhinal (PRH) and medial prefrontal (mPFC) cortices. Here we demonstrate, for the first time, the importance of glutamatergic neurotransmission, within the PRH and mPFC, for object-in-place associative recognition memory. Unilateral blockade of AMPA receptors (by CNQX) in the PRH and mPFC in opposite hemispheres impaired an object-in-place task in rats, confirming that these cortical regions operate within a neural network for object-in-place recognition memory. Intra-mPFC infusions of AP5 (NMDA receptor antagonist) impaired short-term memory and the acquisition of long-term memory, but had no effect on retrieval. AP5 infusions into the PRH disrupted acquisition of long-term memory, but not short-term memory or retrieval. Significantly, crossed AP5 infusions into both the PRH and mPFC disrupted acquisition of long-term memory but were without effect on short-term memory. Finally a unilateral infusion of the selective kainate (GLU(K5)) receptor antagonist UBP302 [(S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione] into the PRH combined with a unilateral infusion of AP5 into the contralateral mPFC significantly impaired short-term object-in-place associative memory. These data show that the PRH and mPFC make distinct contributions to object-in-place associative memory and that the encoding of long-term but not short-term memory requires concurrent NMDA receptor activation in both cortical regions. In contrast, short-term object-in-place memory appears to be dependent on kainate receptor activation in the PRH and NMDA receptor activation in the mPFC

Change in background context disrupts performance on visual paired comparison following hippocampal damage

The medial temporal lobe plays a critical role in recognition memory but, within the medial temporal lobe, the precise neural structures underlying recognition memory remain equivocal. in this study, visual paired comparison (VPC) was used to investigate recognition memory in a human patient (YR), who had a discrete lesion of the hippocampus, and a group of monkeys with neonatal hippocampal lesions, which included the dentate gyrus, and a portion of parahippocampal region. Participants were required to view a picture of an object on a coloured background. Immediately afterwards, this familiar object was shown again, this time paired with a novel object. All participants displayed a novelty preference, provided the background on which the objects were shown was the same as the one used during the learning phase. When the background of the familiar object was changed between initial familiarization and test, only the control subjects showed a novelty preference; the hippocampal-lesioned monkeys and patient YR showed null preference. The results are interpreted within Eichenbaum and Bunsey's [Eichenbaum, H., & Bunsey, M. (1995). On the binding of associations in memory: Clues from studies on the role of the hippocampal region in paired-associate learning. Current Directions in Psychological Science, 4, 19-23] proposal that the hippocampus facilitates the formation of a flexible representation of the elements that make up a stimulus whereas the parahippocampal region is involved in the formation of a fused representation. (C) 2009 Elsevier Ltd. All rights reserved

Hippocampal Infusion of Zeta Inhibitory Peptide Impairs Recent, but Not Remote, Recognition Memory in Rats.

Spatial memory in rodents can be erased following the infusion of zeta inhibitory peptide (ZIP) into the dorsal hippocampus via indwelling guide cannulas. It is believed that ZIP impairs spatial memory by reversing established late-phase long-term potentiation (LTP). However, it is unclear whether other forms of hippocampus-dependent memory, such as recognition memory, are also supported by hippocampal LTP. In the current study, we tested recognition memory in rats following hippocampal ZIP infusion. In order to combat the limited targeting of infusions via cannula, we implemented a stereotaxic approach for infusing ZIP throughout the dorsal, intermediate, and ventral hippocampus. Rats infused with ZIP 3-7 days after training on the novel object recognition task exhibited impaired object recognition memory compared to control rats (those infused with aCSF). In contrast, rats infused with ZIP 1 month after training performed similar to control rats. The ability to form new memories after ZIP infusions remained intact. We suggest that enhanced recognition memory for recent events is supported by hippocampal LTP, which can be reversed by hippocampal ZIP infusion

The positional-specificity effect reveals a passive-trace contribution to visual short-term memory.

The positional-specificity effect refers to enhanced performance in visual short-term memory (VSTM) when the recognition probe is presented at the same location as had been the sample, even though location is irrelevant to the match/nonmatch decision. We investigated the mechanisms underlying this effect with behavioral and fMRI studies of object change-detection performance. To test whether the positional-specificity effect is a direct consequence of active storage in VSTM, we varied memory load, reasoning that it should be observed for all objects presented in a sub-span array of items. The results, however, indicated that although robust with a memory load of 1, the positional-specificity effect was restricted to the second of two sequentially presented sample stimuli in a load-of-2 experiment. An additional behavioral experiment showed that this disruption wasn't due to the increased load per se, because actively processing a second object--in the absence of a storage requirement--also eliminated the effect. These behavioral findings suggest that, during tests of object memory, position-related information is not actively stored in VSTM, but may be retained in a passive tag that marks the most recent site of selection. The fMRI data were consistent with this interpretation, failing to find location-specific bias in sustained delay-period activity, but revealing an enhanced response to recognition probes that matched the location of that trial's sample stimulus

A single-system model predicts recognition memory and repetition priming in amnesia

We challenge the claim that there are distinct neural systems for explicit and implicit memory by demonstrating that a formal single-system model predicts the pattern of recognition memory (explicit) and repetition priming (implicit) in amnesia. In the current investigation, human participants with amnesia categorized pictures of objects at study and then, at test, identified fragmented versions of studied (old) and nonstudied (new) objects (providing a measure of priming), and made a recognition memory judgment (old vs new) for each object. Numerous results in the amnesic patients were predicted in advance by the single-system model, as follows: (1) deficits in recognition memory and priming were evident relative to a control group; (2) items judged as old were identified at greater levels of fragmentation than items judged new, regardless of whether the items were actually old or new; and (3) the magnitude of the priming effect (the identification advantage for old vs new items) overall was greater than that of items judged new. Model evidence measures also favored the single-system model over two formal multiple-systems models. The findings support the single-system model, which explains the pattern of recognition and priming in amnesia primarily as a reduction in the strength of a single dimension of memory strength, rather than a selective explicit memory system deficit

Training methods for facial image comparison: a literature review

This literature review was commissioned to explore the psychological literature relating to facial image comparison with a particular emphasis on whether individuals can be trained to improve performance on this task. Surprisingly few studies have addressed this question directly. As a consequence, this review has been extended to cover training of face recognition and training of different kinds of perceptual comparisons where we are of the opinion that the methodologies or findings of such studies are informative. The majority of studies of face processing have examined face recognition, which relies heavily on memory. This may be memory for a face that was learned recently (e.g. minutes or hours previously) or for a face learned longer ago, perhaps after many exposures (e.g. friends, family members, celebrities). Successful face recognition, irrespective of the type of face, relies on the ability to retrieve the to-berecognised face from long-term memory. This memory is then compared to the physically present image to reach a recognition decision. In contrast, in face matching task two physical representations of a face (live, photographs, movies) are compared and so long-term memory is not involved. Because the comparison is between two present stimuli rather than between a present stimulus and a memory, one might expect that face matching, even if not an easy task, would be easier to do and easier to learn than face recognition. In support of this, there is evidence that judgment tasks where a presented stimulus must be judged by a remembered standard are generally more cognitively demanding than judgments that require comparing two presented stimuli Davies & Parasuraman, 1982; Parasuraman & Davies, 1977; Warm and Dember, 1998). Is there enough overlap between face recognition and matching that it is useful to look at the literature recognition? No study has directly compared face recognition and face matching, so we turn to research in which people decided whether two non-face stimuli were the same or different. In these studies, accuracy of comparison is not always better when the comparator is present than when it is remembered. Further, all perceptual factors that were found to affect comparisons of simultaneously presented objects also affected comparisons of successively presented objects in qualitatively the same way. Those studies involved judgments about colour (Newhall, Burnham & Clark, 1957; Romero, Hita & Del Barco, 1986), and shape (Larsen, McIlhagga & Bundesen, 1999; Lawson, Bülthoff & Dumbell, 2003; Quinlan, 1995). Although one must be cautious in generalising from studies of object processing to studies of face processing (see, e.g., section comparing face processing to object processing), from these kinds of studies there is no evidence to suggest that there are qualitative differences in the perceptual aspects of how recognition and matching are done. As a result, this review will include studies of face recognition skill as well as face matching skill. The distinction between face recognition involving memory and face matching not involving memory is clouded in many recognition studies which require observers to decide which of many presented faces matches a remembered face (e.g., eyewitness studies). And of course there are other forensic face-matching tasks that will require comparison to both presented and remembered comparators (e.g., deciding whether any person in a video showing a crowd is the target person). For this reason, too, we choose to include studies of face recognition as well as face matching in our revie

Associating object names with descriptions of shape that distinguish possible from impossible objects.

Five experiments examine the proposal that object names are closely linked torepresentations of global, 3D shape by comparing memory for simple line drawings of structurally possible and impossible novel objects.Objects were rendered impossible through local edge violations to global coherence (cf. Schacter, Cooper, & Delaney, 1990) and supplementary observations confirmed that the sets of possible and impossible objects were matched for their distinctiveness. Employing a test of explicit recognition memory, Experiment 1 confirmed that the possible and impossible objects were equally memorable. Experiments 2–4 demonstrated that adults learn names (single-syllable non-words presented as count nouns, e.g., “This is a dax”) for possible objectsmore easily than for impossible objects, and an item-based analysis showed that this effect was unrelated to either the memorability or the distinctiveness of the individual objects. Experiment 3 indicated that the effects of object possibility on name learning were long term (spanning at least 2months), implying that the cognitive processes being revealed can support the learning of object names in everyday life. Experiment 5 demonstrated that hearing someone else name an object at presentation improves recognition memory for possible objects, but not for impossible objects. Taken together, the results indicate that object names are closely linked to the descriptions of global, 3D shape that can be derived for structurally possible objects but not for structurally impossible objects. In addition, the results challenge the view that object decision and explicit recognition necessarily draw on separate memory systems,with only the former being supported by these descriptions of global object shape. It seems that recognition also can be supported by these descriptions, provided the original encoding conditions encourage their derivation. Hearing an object named at encoding appears to be just such a condition. These observations are discussed in relation to the effects of naming in other visual tasks, and to the role of visual attention in object identification