Buffalo Arts and Culture Organizations

Open Buffalo and Partnership for the Public Good collaboratively compiled a directory of organizations that promote social justice through locally based arts and cultural programmatic efforts. This directory has contact information, as well as the mission and social justice commitment of the various organizations

Country Snapshot Montenegro

A brief summary of the history and current status of religion in Montenegro

Country Snapshot Serbia

A brief summary of the history and current status of religion in Serbia

Local Government Website Updated Report Card

In 2017, the Buffalo Niagara Coalition for Open Government evaluated the websites of sixteen municipalities in Erie and Niagara County

Gold(III)-pyrrolidinedithiocarbamato Derivatives as Antineoplastic Agents

Transition metals offer many possibilities in developing potent chemotherapeutic agents. They are endowed with a variety of oxidation states, allowing for the selection of their coordination numbers and geometries via the choice of proper ligands, leading to the tuning of their final biological properties. We report here on the synthesis, physico-chemical characterization, and solution behavior of two gold(III) pyrrolidinedithiocarbamates (PDT), namely [AuIIIBr2(PDT)] and [AuIIICl2(PDT)]. We found that the bromide derivative was more effective than the chloride one in inducing cell death for several cancer cell lines. [AuIIIBr2(PDT)] elicited oxidative stress with effects on the permeability transition pore, a mitochondrial channel whose opening leads to cell death. More efficient antineoplastic strategies are required for the widespread burden that is cancer. In line with this, our results indicate that [AuIIIBr2(PDT)] is a promising antineoplastic agent that targets cellular components with crucial functions for the survival of tumor cells

Colloidal Synthesis of Gold Semishells

This work describes a novel and scalable colloid chemistry strategy to fabricate gold semishells based on the selective growth of gold on Janus silica particles (500 nm in diameter) partly functionalized with amino groups. The modulation of the geometry of the Janus silica particles allows us to tune the final morphology of the gold semishells. This method also provides a route to fabricating hollow gold semishells through etching of the silica cores with hydrofluoric acid. The optical properties were characterized by visible near-infrared (vis-NIR) spectroscopy and compared with simulations performed using the boundary element method (BEM). These revealed that the main optical features are located beyond the NIR region because of the large core size

Self-supported polypyrrole/polyvinylsulfate films: electrochemical synthesis, characterization, and sensing properties of their redox reactions

Thick films of polypyrrole/polyvinylsulfate (PPy/PVS) blends were electrogenerated on stainless‐steel electrodes under potentiostatic conditions from aqueous solution. The best electropolymerization potential window was determined by cyclic voltammetry. After removing the film from the back metal, self‐supported electrodes were obtained. Voltammetric, coulovoltammetric, and chronoamperometric responses from a LiClO4 aqueous solution indicated the formation of an energetically stable structure beyond a reduction threshold of the material. Its subsequent oxidation required higher anodic voltammetric overpotentials or longer chronoamperometric oxidation times. This structure was attributed to the formation of lamellar or vacuolar structures. X‐ray photoelectron spectroscopy analysis of the films under different oxidations states revealed that the electrochemical reactions drive the reversible exchange of cations between the film and the electrolyte. The electrical energy and the charge consumed by the reversible reaction of the film under voltammetric conditions between the constant potential limits are a function of the potential scan rate, that is, they sense the working electrochemical conditions.This project was supported by the Marie‐Sklodowska‐Curie Innovative Training Network MICACT‐H2020‐MSCA‐ITN‐2014 and by the Séneca Foundation project 19253/PI/14

State Capacity and Non-state Service Provision in Fragile and Conflict-affected States

How can governments effectively engage with non-state providers (NSPs) of basic services where capacity is weak? This paper examines whether and how fragile and conflict affected states can co-ordinate, finance, and set and apply standards for the provision of basic services by NSPs. It explores ways of incrementally engaging the state, beginning with activities that are least likely to do harm to non-state provision. Through the ‘indirect’ roles of setting the policy environment and engaging in policy dialogue, regulating and facilitating, contracting, and entering into mutual and informal agreements with NSPs, the state can in principle assume responsibility for the provision of basic services without necessarily being involved in direct provision. But government capacity to perform these roles is constrained by the state’s weak legitimacy, coverage and competence, lack of basic information about the non-state sector, and lack of basic organisational capacity to form and maintain relationships with NSPs. The experience of the exercise of the indirect roles in fragile settings suggests: * Governments may be more willing to engage with NSPs where there is recognition that government cannot alone deliver all services, where public and private services are not in competition, and where there is evidence that successful collaboration is possible (demonstrated through small-scale pilots). * The extent to which engagements are ‘pro-service’may be influenced by government motives for engagement and the extent to which the providers that are most important to poor people are engaged. * Formal policy dialogue between government and NSPs may be imperfect, unrepresentative and at times unhelpful in fragile settings. Informal dialogue - at the operational level - could more likely be where synergies can be found. * Regulation is more likely to be ‘pro-service’ where it offers incentives for compliance, and where it focuses on standards in terms of outputs and outcomes rather than inputs and entry controls. * Wide scale, performance-based contracting has been successful in delivering services in some cases, but the sustainability of this approach is often questioned. Some successful contractual agreements have a strong informal, relational element and grow out of earlier informal connections. * Informal and mutual agreements can avoid the capacity problems and tensions implicit in formal contracting but may present problems of non-transparency and exclusion of competition. Paradoxically, the need for large-scale approaches and quick co-ordination of services in fragile and conflict-affected settings may require ‘prematurely high’ levels of state-NSP engagement, before the development of the underlying institutional structures that would support them. When considering strategies to support the capacity of government to engagement with NSPs, donors should: * Recognise non-state service provision and adopt the ‘do no harm’ principle: It would be wrong to set the ambition of 'managing ‘ non-state provision in its entirety, and it can be very harmful for low-capacity states to seek to regulate all NSP or to draw it into clumsy contracts. * Beware of generalisation: Non-state provision takes many forms in response to different histories and to political and economic change. The possibilities and case for state engagement have to be assessed not assumed. The particular identities of NGOs and enterprises should be considered. * Recognise that state building can occur through any of the types of engagement with NSPs: Types of engagement should therefore be selected on the basis of their likely effectiveness in improving service delivery. * Begin with less risky/small scale forms of engagement where possible: State interventions that imply a direct controlling role for the state and which impose obligations on NSPs (i.e. contracting and regulation) require greater capacity (on both sides) and present greater risk of harm if performed badly than the roles of policy dialogue and entering into mutual agreements. * Adopt mixed approaches: The choice between forms of engagement does not have to be absolute. Rather than adopting a uniform plan of engagement in a particular country, it may be better to try different approaches in different regions or sectors

Local Government Authority in Erie and Niagara County Website Report Card

In February of 2018, the Buffalo Niagara Coalition for Open Government evaluated the websites of fourteen local government Authorities in Erie and Niagara Count

Gossip in a Smartphone Peer-to-Peer Network

In this paper, we study the fundamental problem of gossip in the mobile telephone model: a recently introduced variation of the classical telephone model modified to better describe the local peer-to-peer communication services implemented in many popular smartphone operating systems. In more detail, the mobile telephone model differs from the classical telephone model in three ways: (1) each device can participate in at most one connection per round; (2) the network topology can undergo a parameterized rate of change; and (3) devices can advertise a parameterized number of bits about their state to their neighbors in each round before connection attempts are initiated. We begin by describing and analyzing new randomized gossip algorithms in this model under the harsh assumption of a network topology that can change completely in every round. We prove a significant time complexity gap between the case where nodes can advertise $0$ bits to their neighbors in each round, and the case where nodes can advertise $1$ bit. For the latter assumption, we present two solutions: the first depends on a shared randomness source, while the second eliminates this assumption using a pseudorandomness generator we prove to exist with a novel generalization of a classical result from the study of two-party communication complexity. We then turn our attention to the easier case where the topology graph is stable, and describe and analyze a new gossip algorithm that provides a substantial performance improvement for many parameters. We conclude by studying a relaxed version of gossip in which it is only necessary for nodes to each learn a specified fraction of the messages in the system.Comment: Extended Abstract to Appear in the Proceedings of the ACM Conference on the Principles of Distributed Computing (PODC 2017