9,507 research outputs found
Multiple Random Walks to Uncover Short Paths in Power Law Networks
Consider the following routing problem in the context of a large scale
network , with particular interest paid to power law networks, although our
results do not assume a particular degree distribution. A small number of nodes
want to exchange messages and are looking for short paths on . These nodes
do not have access to the topology of but are allowed to crawl the network
within a limited budget. Only crawlers whose sample paths cross are allowed to
exchange topological information. In this work we study the use of random walks
(RWs) to crawl . We show that the ability of RWs to find short paths bears
no relation to the paths that they take. Instead, it relies on two properties
of RWs on power law networks: 1) RW's ability observe a sizable fraction of the
network edges; and 2) an almost certainty that two distinct RW sample paths
cross after a small percentage of the nodes have been visited. We show
promising simulation results on several real world networks
Community-based Immunization Strategies for Epidemic Control
Understanding the epidemic dynamics, and finding out efficient techniques to
control it, is a challenging issue. A lot of research has been done on targeted
immunization strategies, exploiting various global network topological
properties. However, in practice, information about the global structure of the
contact network may not be available. Therefore, immunization strategies that
can deal with a limited knowledge of the network structure are required. In
this paper, we propose targeted immunization strategies that require
information only at the community level. Results of our investigations on the
SIR epidemiological model, using a realistic synthetic benchmark with
controlled community structure, show that the community structure plays an
important role in the epidemic dynamics. An extensive comparative evaluation
demonstrates that the proposed strategies are as efficient as the most
influential global centrality based immunization strategies, despite the fact
that they use a limited amount of information. Furthermore, they outperform
alternative local strategies, which are agnostic about the network structure,
and make decisions based on random walks.Comment: 6 pages, 7 figure
Fundamental structures of dynamic social networks
Social systems are in a constant state of flux with dynamics spanning from
minute-by-minute changes to patterns present on the timescale of years.
Accurate models of social dynamics are important for understanding spreading of
influence or diseases, formation of friendships, and the productivity of teams.
While there has been much progress on understanding complex networks over the
past decade, little is known about the regularities governing the
micro-dynamics of social networks. Here we explore the dynamic social network
of a densely-connected population of approximately 1000 individuals and their
interactions in the network of real-world person-to-person proximity measured
via Bluetooth, as well as their telecommunication networks, online social media
contacts, geo-location, and demographic data. These high-resolution data allow
us to observe social groups directly, rendering community detection
unnecessary. Starting from 5-minute time slices we uncover dynamic social
structures expressed on multiple timescales. On the hourly timescale, we find
that gatherings are fluid, with members coming and going, but organized via a
stable core of individuals. Each core represents a social context. Cores
exhibit a pattern of recurring meetings across weeks and months, each with
varying degrees of regularity. Taken together, these findings provide a
powerful simplification of the social network, where cores represent
fundamental structures expressed with strong temporal and spatial regularity.
Using this framework, we explore the complex interplay between social and
geospatial behavior, documenting how the formation of cores are preceded by
coordination behavior in the communication networks, and demonstrating that
social behavior can be predicted with high precision.Comment: Main Manuscript: 16 pages, 4 figures. Supplementary Information: 39
pages, 34 figure
Temporal networks of face-to-face human interactions
The ever increasing adoption of mobile technologies and ubiquitous services
allows to sense human behavior at unprecedented levels of details and scale.
Wearable sensors are opening up a new window on human mobility and proximity at
the finest resolution of face-to-face proximity. As a consequence, empirical
data describing social and behavioral networks are acquiring a longitudinal
dimension that brings forth new challenges for analysis and modeling. Here we
review recent work on the representation and analysis of temporal networks of
face-to-face human proximity, based on large-scale datasets collected in the
context of the SocioPatterns collaboration. We show that the raw behavioral
data can be studied at various levels of coarse-graining, which turn out to be
complementary to one another, with each level exposing different features of
the underlying system. We briefly review a generative model of temporal contact
networks that reproduces some statistical observables. Then, we shift our focus
from surface statistical features to dynamical processes on empirical temporal
networks. We discuss how simple dynamical processes can be used as probes to
expose important features of the interaction patterns, such as burstiness and
causal constraints. We show that simulating dynamical processes on empirical
temporal networks can unveil differences between datasets that would otherwise
look statistically similar. Moreover, we argue that, due to the temporal
heterogeneity of human dynamics, in order to investigate the temporal
properties of spreading processes it may be necessary to abandon the notion of
wall-clock time in favour of an intrinsic notion of time for each individual
node, defined in terms of its activity level. We conclude highlighting several
open research questions raised by the nature of the data at hand.Comment: Chapter of the book "Temporal Networks", Springer, 2013. Series:
Understanding Complex Systems. Holme, Petter; Saram\"aki, Jari (Eds.
Detection of regulator genes and eQTLs in gene networks
Genetic differences between individuals associated to quantitative phenotypic
traits, including disease states, are usually found in non-coding genomic
regions. These genetic variants are often also associated to differences in
expression levels of nearby genes (they are "expression quantitative trait
loci" or eQTLs for short) and presumably play a gene regulatory role, affecting
the status of molecular networks of interacting genes, proteins and
metabolites. Computational systems biology approaches to reconstruct causal
gene networks from large-scale omics data have therefore become essential to
understand the structure of networks controlled by eQTLs together with other
regulatory genes, and to generate detailed hypotheses about the molecular
mechanisms that lead from genotype to phenotype. Here we review the main
analytical methods and softwares to identify eQTLs and their associated genes,
to reconstruct co-expression networks and modules, to reconstruct causal
Bayesian gene and module networks, and to validate predicted networks in
silico.Comment: minor revision with typos corrected; review article; 24 pages, 2
figure
- …