RandomBoost: Simplified Multi-class Boosting through Randomization

We propose a novel boosting approach to multi-class classification problems, in which multiple classes are distinguished by a set of random projection matrices in essence. The approach uses random projections to alleviate the proliferation of binary classifiers typically required to perform multi-class classification. The result is a multi-class classifier with a single vector-valued parameter, irrespective of the number of classes involved. Two variants of this approach are proposed. The first method randomly projects the original data into new spaces, while the second method randomly projects the outputs of learned weak classifiers. These methods are not only conceptually simple but also effective and easy to implement. A series of experiments on synthetic, machine learning and visual recognition data sets demonstrate that our proposed methods compare favorably to existing multi-class boosting algorithms in terms of both the convergence rate and classification accuracy.Comment: 15 page

A study of hierarchical and flat classification of proteins

Automatic classification of proteins using machine learning is an important problem that has received significant attention in the literature. One feature of this problem is that expert-defined hierarchies of protein classes exist and can potentially be exploited to improve classification performance. In this article we investigate empirically whether this is the case for two such hierarchies. We compare multi-class classification techniques that exploit the information in those class hierarchies and those that do not, using logistic regression, decision trees, bagged decision trees, and support vector machines as the underlying base learners. In particular, we compare hierarchical and flat variants of ensembles of nested dichotomies. The latter have been shown to deliver strong classification performance in multi-class settings. We present experimental results for synthetic, fold recognition, enzyme classification, and remote homology detection data. Our results show that exploiting the class hierarchy improves performance on the synthetic data, but not in the case of the protein classification problems. Based on this we recommend that strong flat multi-class methods be used as a baseline to establish the benefit of exploiting class hierarchies in this area

Utilizing Multi-level Classification Techniques to Predict Adverse Drug Effects and Reactions

Multi-class classification models are used to predict categorical response variables with more than two possible outcomes. A collection of multi-class classification techniques such as Multinomial Logistic Regression, Na\ {i}ve Bayes, and Support Vector Machine is used in predicting patients’ drug reactions and adverse drug effects based on patients’ demographic and drug administration. The newly released 2018 data on drug reactions and adverse drug effects from U.S. Food and Drug Administration are tested with the models. The applicability of model evaluation measures such as sensitivity, specificity and prediction accuracy in multi-class settings, are also discussed