Time-scale and pitch modifications of speech signals and resynthesis from the discrete short-time Fourier transform

The modification methods described in this paper combine characteristics of PSOLA-based methods and algorithms that resynthesize speech from its short-time Fourier magnitude only. The starting point is a short-time Fourier representation of the signal. In the case of duration modification, portions, in voiced speech corresponding to pitch periods, are removed from or inserted in this representation. In the case of pitch modification, pitch periods are shortened or extended in this representation, and a number of pitch periods is inserted or removed, respectively. Since it is an important tool for both duration and pitch modification, the resynthesis-from-short-time-Fourier-magnitude-only method of Griffin and Lim (1984) and Griffin et al. (1984) is reviewed and adapted. Duration and pitch modification methods and their results are presented.\ud \u

Probing medium-induced jet splitting and energy loss in heavy-ion collisions

The nuclear modification of jet splitting in relativistic heavy-ion collisions at RHIC and the LHC energies is studied based on the higher twist formalism. Assuming coherent energy loss for the two splitted subjets, a non-monotonic jet energy dependence is found for the nuclear modification of jet splitting function: strongest modification at intermediate jet energies whereas weaker modification for larger or smaller jet energies. Combined with the smaller size and lower density of the QGP medium at RHIC than at the LHC, this explains the CMS-STAR groomed jet puzzle -- strong nuclear modification of the momentum sharing $z_g$ distribution at the LHC whereas no obvious modification of the $z_g$ distribution at RHIC. In contrast, the observed nuclear modification pattern of the groomed jet $z_g$ distribution cannot be explained solely by independent energy loss of the two subjets. Our result may be tested in future measurements of groomed jets with lower jet energies at the LHC and larger jet energies at RHIC, for different angular separations between the two subjets.Comment: 10 pages, 12 figure

Ethics of modifying the mitochondrial genome

Recent preclinical studies have shown the feasibility of specific variants of nuclear transfer to prevent mitochondrial DNA disorders. Nuclear transfer could be a valuable reproductive option for carriers of mitochondrial mutations. A clinical application of nuclear transfer, however, would entail germ-line modification, more specifically a germ-line modification of the mitochondrial genome. One of the most prominent objections against germ-line modification is the fear that it would become possible to alter 'essential characteristics' of a future person, thereby possibly violating the child's right to an open future. As only the nuclear DNA would contain the ingredients for individual characteristics, modification of the mtDNA is often considered less controversial than modification of the nuclear DNA. This paper discusses the tenability of this dichotomy. After having clarified the concept of germ-line modification, it argues that modification of the mtDNA is not substantively different from modification of the nuclear DNA in terms of its effects on the identity of the future person. Subsequently the paper assesses how this conclusion affects the moral evaluation of nuclear transfer to prevent mtDNA disorders. It concludes that the moral acceptability of germ-line modification does not depend on whether it alters the identity of the future child-all germ-line modifications do-but on whether it safeguards the child's right to an open future. If nuclear transfer to prevent mtDNA disorders becomes safe and effective, then dismissing it because it involves germ-line modification is unjustified

Do Organic Consumers Oppose Genetically Modified Food Stronger than Others? Results of a Consumer Research in Germany

The majority of consumers, in particular European consumers oppose genetic modifi-cation of food. Although consumers oppose strongly genetic modification of food, genetically modified food production increases world wide. The co-existence of both, genetically modified food production and food production free of genetic modification cannot be ensured. There is always a risk that non-genetically modified food gets contaminated despite safety regulations. Thus, even organic production, which is supposed to be free of genetic modification, is endangered and can maybe not ensure to produce food definitely free of genetic modification. Against that background, this consumer research focuses on organic consumers and their attitudes towards geneti-cally modified food. The findings indicate clearly that organic consumer oppose ge-netically modified food stronger than others

Jet modification in the next decade: a pedestrian outlook

In this review, intended for non-specialists and beginners, we recount the current status of the theory of jet modification in dense matter. We commence with an outline of the "traditional" observables which may be calculated without recourse to event generators. These include single and double hadron suppression, nuclear modification factor versus reaction plane etc. All of these measurements are used to justify both the required underlying physical picture of jet modification as well as the final obtained values of jet transport coefficients. This is followed by a review of the more modern observables which have arisen with the ability to reconstruct full jets, and the challenges faced therein. This is followed by a preview of upcoming theoretical developments in the field and an outlook on how the interface between these developments, phenomenological improvements, and upcoming data will allow us to quantitatively determine properties of the medium which effect the modification of hard jets.Comment: 21 pages, 10 figure

Coupling Right- and Left-Handed Photons Differently to Charged Matter

We consider a modification of electrodynamics in which right- and left-circularly polarized photons are coupled to charged sources differently. Even though photon helicity is a Lorentz invariant quantity, such a modification breaks Lorentz symmetry, as well as locality. The modified theory includes novel magnetic forces between perpendicular currents. Existing data can be used to constrain the modification at approximately a 2 x 10^(-3) level.Comment: 12 page