Modeling Small Oscillating Biological Networks in Analog VLSI

We have used analog VLSI technology to model a class of small oscillating biological neural circuits known as central pattern generators (CPG). These circuits generate rhythmic patterns of activity which drive locomotor behaviour in the animal. We have designed, fabricated, and tested a model neuron circuit which relies on many of the same mechanisms as a biological central pattern generator neuron, such as delays and internal feedback. We show that this neuron can be used to build several small circuits based on known biological CPG circuits, and that these circuits produce patterns of output which are very similar to the observed biological patterns

VLSI analogs of neuronal visual processing: a synthesis of form and function

This thesis describes the development and testing of a simple visual system fabricated using complementary metal-oxide-semiconductor (CMOS) very large scale integration (VLSI) technology. This visual system is composed of three subsystems. A silicon retina, fabricated on a single chip, transduces light and performs signal processing in a manner similar to a simple vertebrate retina. A stereocorrespondence chip uses bilateral retinal input to estimate the location of objects in depth. A silicon optic nerve allows communication between chips by a method that preserves the idiom of action potential transmission in the nervous system. Each of these subsystems illuminates various aspects of the relationship between VLSI analogs and their neurobiological counterparts. The overall synthetic visual system demonstrates that analog VLSI can capture a significant portion of the function of neural structures at a systems level, and concomitantly, that incorporating neural architectures leads to new engineering approaches to computation in VLSI. The relationship between neural systems and VLSI is rooted in the shared limitations imposed by computing in similar physical media. The systems discussed in this text support the belief that the physical limitations imposed by the computational medium significantly affect the evolving algorithm. Since circuits are essentially physical structures, I advocate the use of analog VLSI as powerful medium of abstraction, suitable for understanding and expressing the function of real neural systems. The working chip elevates the circuit description to a kind of synthetic formalism. The behaving physical circuit provides a formal test of theories of function that can be expressed in the language of circuits