14,803 research outputs found
Improving Unsupervised Defect Segmentation by Applying Structural Similarity to Autoencoders
Convolutional autoencoders have emerged as popular methods for unsupervised
defect segmentation on image data. Most commonly, this task is performed by
thresholding a pixel-wise reconstruction error based on an distance.
This procedure, however, leads to large residuals whenever the reconstruction
encompasses slight localization inaccuracies around edges. It also fails to
reveal defective regions that have been visually altered when intensity values
stay roughly consistent. We show that these problems prevent these approaches
from being applied to complex real-world scenarios and that it cannot be easily
avoided by employing more elaborate architectures such as variational or
feature matching autoencoders. We propose to use a perceptual loss function
based on structural similarity which examines inter-dependencies between local
image regions, taking into account luminance, contrast and structural
information, instead of simply comparing single pixel values. It achieves
significant performance gains on a challenging real-world dataset of
nanofibrous materials and a novel dataset of two woven fabrics over the state
of the art approaches for unsupervised defect segmentation that use pixel-wise
reconstruction error metrics
Task adapted reconstruction for inverse problems
The paper considers the problem of performing a task defined on a model
parameter that is only observed indirectly through noisy data in an ill-posed
inverse problem. A key aspect is to formalize the steps of reconstruction and
task as appropriate estimators (non-randomized decision rules) in statistical
estimation problems. The implementation makes use of (deep) neural networks to
provide a differentiable parametrization of the family of estimators for both
steps. These networks are combined and jointly trained against suitable
supervised training data in order to minimize a joint differentiable loss
function, resulting in an end-to-end task adapted reconstruction method. The
suggested framework is generic, yet adaptable, with a plug-and-play structure
for adjusting both the inverse problem and the task at hand. More precisely,
the data model (forward operator and statistical model of the noise) associated
with the inverse problem is exchangeable, e.g., by using neural network
architecture given by a learned iterative method. Furthermore, any task that is
encodable as a trainable neural network can be used. The approach is
demonstrated on joint tomographic image reconstruction, classification and
joint tomographic image reconstruction segmentation
Whole-brain vasculature reconstruction at the single capillary level
The distinct organization of the brain’s vascular network ensures that it is adequately supplied with oxygen and nutrients. However, despite this fundamental role, a detailed reconstruction of the brain-wide vasculature at the capillary level remains elusive, due to insufficient image quality using the best available techniques. Here, we demonstrate a novel approach that improves vascular demarcation by combining CLARITY with a vascular staining approach that can fill the entire blood vessel lumen and imaging with light-sheet fluorescence microscopy. This method significantly improves image contrast, particularly in depth, thereby allowing reliable application of automatic segmentation algorithms, which play an increasingly important role in high-throughput imaging of the terabyte-sized datasets now routinely produced. Furthermore, our novel method is compatible with endogenous fluorescence, thus allowing simultaneous investigations of vasculature and genetically targeted neurons. We believe our new method will be valuable for future brain-wide investigations of the capillary network
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