Intervertebral disc characterization by shear wave elastography: an in-vitro preliminary study

Patient-specific numerical simulation of the spine is a useful tool both in clinic and research. While geometrical personalization of the spine is no more an issue, thanks to recent technological advances, non-invasive personalization of soft tissue’s mechanical properties remains a challenge. Ultrasound elastography is a relatively recent measurement technique allowing the evaluation of soft tissue’s elastic modulus through the measurement of shear wave speed (SWS). The aim of this study was to determine the feasibility of elastographic measurements in intervertebral disc (IVD). An in-vitro approach was chosen to test the hypothesis that SWS can be used to evaluate IVD mechanical properties and to assess measurement repeatability. Eleven oxtail IVDs were tested in compression to determine their stiffness and apparent elastic modulus at rest and at 400 N. Elastographic measurements were performed in these two conditions and compared to these mechanical parameters. The protocol was repeated six times to determine elastographic measurement repeatability. Average SWS over all samples was 5.3 ± 1.0 m/s, with a repeatability of 7 % at rest and 4.6 % at 400 N; stiffness and apparent elastic modulus were 266.3 ± 70.5 N/mm and 5.4 ± 1.1 MPa at rest, respectively, while at 400 N they were 781.0 ± 153.8 N/mm and 13.2 ± 2.4 MPa. Correlations were found between elastographic measurements and IVD mechanical properties; these preliminary results are promising for further in-vivo application.The authors are grateful to the ParisTech BiomecAM chair program on subject-specific musculoskeletal modelling for funding (with the support of Proteor, ParisTech and Yves Cotrel Foundations)

CMB anisotropy: deviations from Gaussianity due to non-linear gravity

Non-linear evolution of cosmological energy density fluctuations triggers deviations from Gaussianity in the temperature distribution of the cosmic microwave background. A method to estimate these deviations is proposed. N-body simulations -- in a $\Lambda$CDM cosmology -- are used to simulate the strongly non-linear evolution of cosmological structures. It is proved that these simulations can be combined with the potential approximation to calculate the statistical moments of the CMB anisotropies produced by non-linear gravity. Some of these moments are computed and the resulting values are different from those corresponding to Gaussianity.Comment: 6 latex pages with mn.sty, 3 eps figures. Accepted in MNRA

On the complete solution of the general quintic using Rogers-Ramanujan continued fraction

In this article we give solution of the general quintic equation by means of the Rogers-Ramanujan continued fraction. More precisely we express a root of the quintic as a known algebraic function of the Rogers-Ramanujan continued fraction.Comment: Quintic Equation, Rogers-Ramanujan Continued Fractio

Rethinking Zero-shot Video Classification: End-to-end Training for Realistic Applications

Trained on large datasets, deep learning (DL) can accurately classify videos into hundreds of diverse classes. However, video data is expensive to annotate. Zero-shot learning (ZSL) proposes one solution to this problem. ZSL trains a model once, and generalizes to new tasks whose classes are not present in the training dataset. We propose the first end-to-end algorithm for ZSL in video classification. Our training procedure builds on insights from recent video classification literature and uses a trainable 3D CNN to learn the visual features. This is in contrast to previous video ZSL methods, which use pretrained feature extractors. We also extend the current benchmarking paradigm: Previous techniques aim to make the test task unknown at training time but fall short of this goal. We encourage domain shift across training and test data and disallow tailoring a ZSL model to a specific test dataset. We outperform the state-of-the-art by a wide margin. Our code, evaluation procedure and model weights are available at this http URL

Nanotechnology for high frequency communications: nitrides and graphene

The achievement of higher frequencies (HF) and the reduction of energy consumption, to improve sensing, communication and computation, involve the continued scaling down to the nanometer level. This scaling is enabled by of innovative device designs, improved processing technologies and assessment tools, and new material structures. In this work, we have used all these factors to demonstrate state-of-the-art HF devices in two materials with quite different electronic properties: wide semiconductor bandgap III-nitrides for resonators and power amplifiers; and graphene, a zero bandgap material expected to revolutionize low noise and HF flexible electronics. Some issues faced during their development will be discussed during the talk

Postcranial remains of Fabrosauridae (Reptilia: Ornithischia) from the Stormberg of southern Africa

The postcranial skeletons of three fabrosaurids from the upper Elliot Formation "Red Beds" of the Stormberg Group in southern Africa are described. The material demonstrates details of fabrosaurid anatomy previously unknown, particularly a short, deep prepubic process which is undoubtedly primitive for the Ornithischia. Besides the short prepubis, fabrosaurids are characterized by 1) a reduced manus; 2) an ilium having a lateral extension of the supra-acetabular margin and a deep nearly vertical brevis shelf; and 3) an elongated hindlimb. Postcranial morphology excludes the fabrosaurids from the ancestry of the contemporaneous heterodontosaurids. Neither can the fabrosaurids be considered ancestral to the 'juvenile scelidosaurid' (BMNH R6704) as has been suggested. On the contrary, the 'scelidosaurid' is more primitive in structure than fabrosaurids. The assignment of Nanosaurus agilis Marsh to the Fabrosauridae is not substantiated after morphological comparisons between the postcranial material of both. The taxonomic status of Scutellosaurus lawleri is regarded as uncertain. The fabrosaurids are more similar to the Morrison Formation camptosaurids, than to Hypsilophodon. Finally, it is argued that ornithopods were not a basal stock for the phylogenesis of non-ornithopods but represent an independent radiation comparable to the other ornithischian suborders. The fabrosaurids were an early development of the ornithopod radiation itself