95 research outputs found

    The Palgrave handbook of global slavery throughout history

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    This open access handbook takes a comparative and global approach to analyse the practice of slavery throughout history. To understand slavery - why it developed, and how it functioned in various societies – is to understand an important and widespread practice in world civilisations. With research traditionally being dominated by the Atlantic world, this collection aims to illuminate slavery that existed in not only the Americas but also ancient, medieval, North and sub-Saharan African, Near Eastern, and Asian societies. Connecting civilisations through migration, warfare, trade routes and economic expansion, the practice of slavery integrated countries and regions through power-based relationships, whilst simultaneously dividing societies by class, race, ethnicity and cultural group. Uncovering slavery as a globalising phenomenon, the authors highlight the slave-trading routes that crisscrossed Africa, helped integrate the Mediterranean world, connected Indian Ocean societies and fused the Atlantic world. Split into five parts, the handbook portrays the evolution of slavery from antiquity to the contemporary era and encourages readers to realise similarities and differences between various manifestations of slavery throughout history. Providing a truly global coverage of slavery, and including thematic injections within each chronological part, this handbook is a comprehensive and transnational resource for all researchers interested in slavery, the history of labour, and anthropology.Cities, Migration and Global Interdependence 1350-200

    Biotechnology to Combat COVID-19

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    This book provides an inclusive and comprehensive discussion of the transmission, science, biology, genome sequencing, diagnostics, and therapeutics of COVID-19. It also discusses public and government health measures and the roles of media as well as the impact of society on the ongoing efforts to combat the global pandemic. It addresses almost every topic that has been studied so far in the research on SARS-CoV-2 to gain insights into the fundamentals of the disease and mitigation strategies. This volume is a useful resource for virologists, epidemiologists, biologists, medical professionals, public health and government professionals, and all global citizens who have endured and battled against the pandemic

    Nutritional Habits and Interventions in Childhood

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    The objective of this book is to present nutritional and educational interventions for children and their families. The creation of healthy preferences is a key determinant of food choices and therefore diet quality. Food choices have important implications for health, particularly for food-related diseases, such as feeding difficulties and the development of non-communicable diseases. The first years of a child's life are fundamental for the creation of tastes, eating habits and the relationship with food. Preferences for certain foods are neither innate nor unchangeable. Eating behaviour is the result of experience and learning, and, through the repeated offering of food by parents, especially those less accepted, it is possible to promote good nutrition. Behaviour depends on the interaction of environmental factors, genetics, sex, and age. The environment in which the child is immersed, and which influences them, includes family, other children, society, media and the supply of food. Achieving an adequate intake of macro and micro-nutrients is an important objective for all ages of life and, particularly, for those of pediatric age, since it is crucial for cognitive development. Nutrition has also a therapeutic effect. Nutritional interventions tailored to specific pathologies are needed to prevent nutritional deficiencies and maintain an adequate nutritional status, since children and adolescents with chronic or inflammatory diseases are particularly vulnerable and at major risk of developing malnutrition

    Routledge Handbook of Chinese Medicine

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    The Routledge Handbook of Chinese Medicine is an extensive, interdisciplinary guide to the nature of traditional medicine and healing in the Chinese cultural region, and its plural epistemologies. Established experts and the next generation of scholars interpret the ways in which Chinese medicine has been understood and portrayed from the beginning of the empire (third century BCE) to the globalisation of Chinese products and practices in the present day, taking in subjects from ancient medical writings to therapeutic movement, to talismans for healing and traditional medicines that have inspired global solutions to contemporary epidemics. The volume is divided into seven parts: Longue Durée and Formation of Institutions and Traditions Sickness and Healing Food and Sex Spiritual and Orthodox Religious Practices The World of Sinographic Medicine Wider Diasporas Negotiating Modernity This handbook therefore introduces the broad range of ideas and techniques that comprise pre-modern medicine in China, and the historiographical and ethnographic approaches that have illuminated them. It will prove a useful resource to students and scholars of Chinese studies, and the history of medicine and anthropology. It will also be of interest to practitioners, patients and specialists wishing to refresh their knowledge with the latest developments in the field. The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 licens

    Evaluation of PD-L1 expression in various formalin-fixed paraffin embedded tumour tissue samples using SP263, SP142 and QR1 antibody clones

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    Background & objectives: Cancer cells can avoid immune destruction through the inhibitory ligand PD-L1. PD-1 is a surface cell receptor, part of the immunoglobulin family. Its ligand PD-L1 is expressed by tumour cells and stromal tumour infltrating lymphocytes (TIL). Methods: Forty-four cancer cases were included in this study (24 triple-negative breast cancers (TNBC), 10 non-small cell lung cancer (NSCLC) and 10 malignant melanoma cases). Three clones of monoclonal primary antibodies were compared: QR1 (Quartett), SP 142 and SP263 (Ventana). For visualization, ultraView Universal DAB Detection Kit from Ventana was used on an automated platform for immunohistochemical staining Ventana BenchMark GX. Results: Comparing the sensitivity of two different clones on same tissue samples from TNBC, we found that the QR1 clone gave higher percentage of positive cells than clone SP142, but there was no statistically significant difference. Comparing the sensitivity of two different clones on same tissue samples from malignant melanoma, the SP263 clone gave higher percentage of positive cells than the QR1 clone, but again the difference was not statistically significant. Comparing the sensitivity of two different clones on same tissue samples from NSCLC, we found higher percentage of positive cells using the QR1 clone in comparison with the SP142 clone, but once again, the difference was not statistically significant. Conclusion: The three different antibody clones from two manufacturers Ventana and Quartett, gave comparable results with no statistically significant difference in staining intensity/ percentage of positive tumour and/or immune cells. Therefore, different PD-L1 clones from different manufacturers can potentially be used to evaluate the PD- L1 status in different tumour tissues. Due to the serious implications of the PD-L1 analysis in further treatment decisions for cancer patients, every antibody clone, staining protocol and evaluation process should be carefully and meticulously validated

    From Photography to fMRI

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    Hysteria, a mysterious disease known since antiquity, is said to have ceased to exist. Challenging this commonly held view, this is the first cross-disciplinary study to examine the current functional neuroimaging research into hysteria and compare it to the nineteenth-century image-based research into the same disorder. Paula Muhr's central argument is that, both in the nineteenth-century and the current neurobiological research on hysteria, images have enabled researchers to generate new medical insights. Through detailed case studies, Muhr traces how different images, from photography to functional brain scans, have reshaped the historically situated medical understanding of this disorder that defies the mind-body dualism
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