Deep learning cardiac motion analysis for human survival prediction

Motion analysis is used in computer vision to understand the behaviour of moving objects in sequences of images. Optimising the interpretation of dynamic biological systems requires accurate and precise motion tracking as well as efficient representations of high-dimensional motion trajectories so that these can be used for prediction tasks. Here we use image sequences of the heart, acquired using cardiac magnetic resonance imaging, to create time-resolved three-dimensional segmentations using a fully convolutional network trained on anatomical shape priors. This dense motion model formed the input to a supervised denoising autoencoder (4Dsurvival), which is a hybrid network consisting of an autoencoder that learns a task-specific latent code representation trained on observed outcome data, yielding a latent representation optimised for survival prediction. To handle right-censored survival outcomes, our network used a Cox partial likelihood loss function. In a study of 302 patients the predictive accuracy (quantified by Harrell's C-index) was significantly higher (p < .0001) for our model C=0.73 (95$\%$ CI: 0.68 - 0.78) than the human benchmark of C=0.59 (95$\%$ CI: 0.53 - 0.65). This work demonstrates how a complex computer vision task using high-dimensional medical image data can efficiently predict human survival

ToyArchitecture: Unsupervised Learning of Interpretable Models of the World

Research in Artificial Intelligence (AI) has focused mostly on two extremes: either on small improvements in narrow AI domains, or on universal theoretical frameworks which are usually uncomputable, incompatible with theories of biological intelligence, or lack practical implementations. The goal of this work is to combine the main advantages of the two: to follow a big picture view, while providing a particular theory and its implementation. In contrast with purely theoretical approaches, the resulting architecture should be usable in realistic settings, but also form the core of a framework containing all the basic mechanisms, into which it should be easier to integrate additional required functionality. In this paper, we present a novel, purposely simple, and interpretable hierarchical architecture which combines multiple different mechanisms into one system: unsupervised learning of a model of the world, learning the influence of one's own actions on the world, model-based reinforcement learning, hierarchical planning and plan execution, and symbolic/sub-symbolic integration in general. The learned model is stored in the form of hierarchical representations with the following properties: 1) they are increasingly more abstract, but can retain details when needed, and 2) they are easy to manipulate in their local and symbolic-like form, thus also allowing one to observe the learning process at each level of abstraction. On all levels of the system, the representation of the data can be interpreted in both a symbolic and a sub-symbolic manner. This enables the architecture to learn efficiently using sub-symbolic methods and to employ symbolic inference.Comment: Revision: changed the pdftitl

Multichannel Attention Network for Analyzing Visual Behavior in Public Speaking

Public speaking is an important aspect of human communication and interaction. The majority of computational work on public speaking concentrates on analyzing the spoken content, and the verbal behavior of the speakers. While the success of public speaking largely depends on the content of the talk, and the verbal behavior, non-verbal (visual) cues, such as gestures and physical appearance also play a significant role. This paper investigates the importance of visual cues by estimating their contribution towards predicting the popularity of a public lecture. For this purpose, we constructed a large database of more than $1800$ TED talk videos. As a measure of popularity of the TED talks, we leverage the corresponding (online) viewers' ratings from YouTube. Visual cues related to facial and physical appearance, facial expressions, and pose variations are extracted from the video frames using convolutional neural network (CNN) models. Thereafter, an attention-based long short-term memory (LSTM) network is proposed to predict the video popularity from the sequence of visual features. The proposed network achieves state-of-the-art prediction accuracy indicating that visual cues alone contain highly predictive information about the popularity of a talk. Furthermore, our network learns a human-like attention mechanism, which is particularly useful for interpretability, i.e. how attention varies with time, and across different visual cues by indicating their relative importance