11,333 research outputs found

    Integration of HeartSmart Kids into Clinical Practice: A Quality Improvement Project

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    Presented to the Faculty of the University of Alaska, Anchorage in partial fulfillment of requirements for the degree of MASTER OF SCIENCE, FAMILY PRACTICE NURSEIn 2009, the Centers for Medicare & Medicaid (CMS), established “Meaningful Use” regulations through an incentive program, as part of the American Recovery and Reinvestment Act of 2009 (Gance-Cleveland, Gilbert, Gilbert, Dandreaux, & Russell, 2014). Meaningful Use (MU) is tied to reimbursement and focuses on how the Electronic Health Record (EHR) is being used (Center for Disease Control and Prevention, 2012). The goal of MU is to transform the use of the EHR from a documentation tool, to a data reservoir which allows for meaningful reviews and interpretations of the quality of care (Gance-Cleveland et al, 2014).Project / Background / Significance / Review of Literature / Problem Overview / Problem Statement / Purpose / Design / Method / Plan Do Study Act (PDSA) / Ethical Considerations / Significance to Nursing / Dissemination / Conclusion

    A Peroxisomal Lon Protease and Peroxisome Degradation by Autophagy Play Key Roles in Vitality of Hansenula polymorpha Cells

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    In eukaryote cells various mechanisms exist that are responsible for the removal of non-functional proteins. Here we show that in the yeast Hansenula polymorpha (H. polymorpha) a peroxisomal Lon protease, Pln, plays a role in degradation of unfolded and non-assembled peroxisomal matrix proteins. In addition, we demonstrate that whole peroxisomes are constitutively degraded by autophagy during normal vegetative growth of WT cells. Deletion of both H. polymorpha PLN and ATG1, required for autophagy, resulted in a significant increase in peroxisome numbers, paralleled by a decrease in cell viability relative to WT cells. Also, in these cells and in cells of PLN and ATG1 single deletion strains, the intracellular levels of reactive oxygen species had increased relative to WT controls. The enhanced generation of reactive oxygen species may be related to an uneven distribution of peroxisomal catalase activities in the mutant cells, as demonstrated by cytochemistry. We speculate that in the absence of HpPln or autophagy unfolded and non-assembled peroxisomal matrix proteins accumulate, which can form aggregates and lead to an imbalance in hydrogen peroxide production and degradation in some of the organelles.

    Intergration of Intentional Research Assignments into Select Nursing Courses

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    Undergraduate Applie

    Intergration of control chart and pattern recognizer for bivariate quality control

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    Monitoring and diagnosis of mean shifts in manufacturing processes become more challenging when involving two or more correlated variables. Unfortunately, most of the existing multivariate statistical process control schemes are only effective in rapid detection but suffer high false alarm. This is referred to as imbalanced performance monitoring. The problem becomes more complicated when dealing with small mean shift particularly in identifying the causable variables. In this research, a scheme that integrated the control charting and pattern recognition technique has been investigated toward improving the quality control (QC) performance. Design considerations involved extensive simulation experiments to select input representation based on raw data and statistical features, recognizer design structure based on individual and Statistical Features-ANN models, and monitoring-diagnosis approach based on single stage and two stages techniques. The study focuses on correlated process mean shifts for cross correlation function, ρ = 0.1, 0.5, 0.9, and mean shift, μ = ± 0.75 ~ 3.00 standard deviations. Among the investigated design, an Integrated Multivariate Exponentially Weighted Moving Average with Artificial Neural Network scheme provides superior performance, namely the Average Run Length for grand average ARL1 = 7.55 7.78 ( for out-of-control) and ARL0 = 491.03 (small mean shift) and 524.80 (large mean shift) in control process and the grand average for recognition accuracy (RA) = 96.36 98.74. This research has provided a new perspective in realizing balanced monitoring and accurate diagnosis of correlated process mean shifts

    Pan-Arabism v. Pan-Africanism in the Sudan: The Crisis of Divergent Ethnic Ideologies

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    This article examines the nature and the extent of political and cultural conflict between Northern and Southern Sudanese. It describes and analyzes various attempts by Arab dominated regimes in the Sudan, since independence from Britain, to achieve national intergration[integration] through Pan-Arabist policies that seek to Islamize and Arabize the African and largely Christian South. The current military regime dominated by Muslim fundamentalists is trying to turn the Sudan into an Islamic republic. Not only has this brought about a civil war, but it has also alienated other Muslims in the North who favor a secular government

    A numerical method for solving the Vlasov equation

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    A numerical procedure is derived for the solution of the Vlasov-Poisson system of equations in two phase-space variables. Derivatives with respect to the phase-space variables are approximated by a weighted sum of the values of the distribution function at property chosen neighboring points. The resulting set of ordinary differential equations is then solved by using an appropriate time intergration scheme. The accuracy of the proposed method is tested with some simple model problems. The results for the free streaming case, linear Landau damping, and nonlinear Landau damping are investigated and compared with those of the splitting scheme. The proposed method is found to be very accurate and efficient

    U.S. PERSPECTIVES ON EAST ASIAN ECONOMIC INTEGRATION

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    USA only major trade power with equal economic stakes in all regions, and will oppose Asian economic integration if it excludes USA. Charts show relatively declining US role, rising China role as key trade partner for Japan, Korea, ASEAN. Responding to China¡¯s lead, as in its ASEAN trade deals, and shaped by former USTR Zoellick, there is growing US support for bilateral trade agreements, including Korea-US FTA, though most economists oppose bilateral/regional approach as inconsistent with the WTO-multilateral trade format. From US perspective, prognosis for East Asian economic integration not good.Economic Integration, APEC, FTA, ASEAN, Asian Economy, CAFTA, WTO

    Management Of Building Projects

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    In this work we have shown the concept of logistic support in management in building production and in building of objects, which is realised in Enterprise resource Planning – ERP system ERPINSG, developed in Informatic firm Informatic engineering – ININ in Slavonski Brod, and in cooperation with scientists of catedra for informatics of Faculty of Mechanical Engineering and users from building firms.manufacturing logistic, management, ERP systems, ERPINSG
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