13,820 research outputs found
Machine learning methods for histopathological image analysis
Abundant accumulation of digital histopathological images has led to the
increased demand for their analysis, such as computer-aided diagnosis using
machine learning techniques. However, digital pathological images and related
tasks have some issues to be considered. In this mini-review, we introduce the
application of digital pathological image analysis using machine learning
algorithms, address some problems specific to such analysis, and propose
possible solutions.Comment: 23 pages, 4 figure
Context-based Normalization of Histological Stains using Deep Convolutional Features
While human observers are able to cope with variations in color and
appearance of histological stains, digital pathology algorithms commonly
require a well-normalized setting to achieve peak performance, especially when
a limited amount of labeled data is available. This work provides a fully
automated, end-to-end learning-based setup for normalizing histological stains,
which considers the texture context of the tissue. We introduce Feature Aware
Normalization, which extends the framework of batch normalization in
combination with gating elements from Long Short-Term Memory units for
normalization among different spatial regions of interest. By incorporating a
pretrained deep neural network as a feature extractor steering a pixelwise
processing pipeline, we achieve excellent normalization results and ensure a
consistent representation of color and texture. The evaluation comprises a
comparison of color histogram deviations, structural similarity and measures
the color volume obtained by the different methods.Comment: In: 3rd Workshop on Deep Learning in Medical Image Analysis (DLMIA
2017
Interpreting Deep Visual Representations via Network Dissection
The success of recent deep convolutional neural networks (CNNs) depends on
learning hidden representations that can summarize the important factors of
variation behind the data. However, CNNs often criticized as being black boxes
that lack interpretability, since they have millions of unexplained model
parameters. In this work, we describe Network Dissection, a method that
interprets networks by providing labels for the units of their deep visual
representations. The proposed method quantifies the interpretability of CNN
representations by evaluating the alignment between individual hidden units and
a set of visual semantic concepts. By identifying the best alignments, units
are given human interpretable labels across a range of objects, parts, scenes,
textures, materials, and colors. The method reveals that deep representations
are more transparent and interpretable than expected: we find that
representations are significantly more interpretable than they would be under a
random equivalently powerful basis. We apply the method to interpret and
compare the latent representations of various network architectures trained to
solve different supervised and self-supervised training tasks. We then examine
factors affecting the network interpretability such as the number of the
training iterations, regularizations, different initializations, and the
network depth and width. Finally we show that the interpreted units can be used
to provide explicit explanations of a prediction given by a CNN for an image.
Our results highlight that interpretability is an important property of deep
neural networks that provides new insights into their hierarchical structure.Comment: *B. Zhou and D. Bau contributed equally to this work. 15 pages, 27
figure
Multilayer Complex Network Descriptors for Color-Texture Characterization
A new method based on complex networks is proposed for color-texture
analysis. The proposal consists on modeling the image as a multilayer complex
network where each color channel is a layer, and each pixel (in each color
channel) is represented as a network vertex. The network dynamic evolution is
accessed using a set of modeling parameters (radii and thresholds), and new
characterization techniques are introduced to capt information regarding within
and between color channel spatial interaction. An automatic and adaptive
approach for threshold selection is also proposed. We conduct classification
experiments on 5 well-known datasets: Vistex, Usptex, Outex13, CURet and MBT.
Results among various literature methods are compared, including deep
convolutional neural networks with pre-trained architectures. The proposed
method presented the highest overall performance over the 5 datasets, with 97.7
of mean accuracy against 97.0 achieved by the ResNet convolutional neural
network with 50 layers.Comment: 20 pages, 7 figures and 4 table
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