12,917 research outputs found
Deep Learning in Cardiology
The medical field is creating large amount of data that physicians are unable
to decipher and use efficiently. Moreover, rule-based expert systems are
inefficient in solving complicated medical tasks or for creating insights using
big data. Deep learning has emerged as a more accurate and effective technology
in a wide range of medical problems such as diagnosis, prediction and
intervention. Deep learning is a representation learning method that consists
of layers that transform the data non-linearly, thus, revealing hierarchical
relationships and structures. In this review we survey deep learning
application papers that use structured data, signal and imaging modalities from
cardiology. We discuss the advantages and limitations of applying deep learning
in cardiology that also apply in medicine in general, while proposing certain
directions as the most viable for clinical use.Comment: 27 pages, 2 figures, 10 table
Histopathological image analysis : a review
Over the past decade, dramatic increases in computational power and improvement in image analysis algorithms have allowed the development of powerful computer-assisted analytical approaches to radiological data. With the recent advent of whole slide digital scanners, tissue histopathology slides can now be digitized and stored in digital image form. Consequently, digitized tissue histopathology has now become amenable to the application of computerized image analysis and machine learning techniques. Analogous to the role of computer-assisted diagnosis (CAD) algorithms in medical imaging to complement the opinion of a radiologist, CAD algorithms have begun to be developed for disease detection, diagnosis, and prognosis prediction to complement the opinion of the pathologist. In this paper, we review the recent state of the art CAD technology for digitized histopathology. This paper also briefly describes the development and application of novel image analysis technology for a few specific histopathology related problems being pursued in the United States and Europe
Trustworthy clinical AI solutions: a unified review of uncertainty quantification in deep learning models for medical image analysis
The full acceptance of Deep Learning (DL) models in the clinical field is
rather low with respect to the quantity of high-performing solutions reported
in the literature. Particularly, end users are reluctant to rely on the rough
predictions of DL models. Uncertainty quantification methods have been proposed
in the literature as a potential response to reduce the rough decision provided
by the DL black box and thus increase the interpretability and the
acceptability of the result by the final user. In this review, we propose an
overview of the existing methods to quantify uncertainty associated to DL
predictions. We focus on applications to medical image analysis, which present
specific challenges due to the high dimensionality of images and their quality
variability, as well as constraints associated to real-life clinical routine.
We then discuss the evaluation protocols to validate the relevance of
uncertainty estimates. Finally, we highlight the open challenges of uncertainty
quantification in the medical field
On Using Active Learning and Self-Training when Mining Performance Discussions on Stack Overflow
Abundant data is the key to successful machine learning. However, supervised
learning requires annotated data that are often hard to obtain. In a
classification task with limited resources, Active Learning (AL) promises to
guide annotators to examples that bring the most value for a classifier. AL can
be successfully combined with self-training, i.e., extending a training set
with the unlabelled examples for which a classifier is the most certain. We
report our experiences on using AL in a systematic manner to train an SVM
classifier for Stack Overflow posts discussing performance of software
components. We show that the training examples deemed as the most valuable to
the classifier are also the most difficult for humans to annotate. Despite
carefully evolved annotation criteria, we report low inter-rater agreement, but
we also propose mitigation strategies. Finally, based on one annotator's work,
we show that self-training can improve the classification accuracy. We conclude
the paper by discussing implication for future text miners aspiring to use AL
and self-training.Comment: Preprint of paper accepted for the Proc. of the 21st International
Conference on Evaluation and Assessment in Software Engineering, 201
A Two-stage Classification Method for High-dimensional Data and Point Clouds
High-dimensional data classification is a fundamental task in machine
learning and imaging science. In this paper, we propose a two-stage multiphase
semi-supervised classification method for classifying high-dimensional data and
unstructured point clouds. To begin with, a fuzzy classification method such as
the standard support vector machine is used to generate a warm initialization.
We then apply a two-stage approach named SaT (smoothing and thresholding) to
improve the classification. In the first stage, an unconstraint convex
variational model is implemented to purify and smooth the initialization,
followed by the second stage which is to project the smoothed partition
obtained at stage one to a binary partition. These two stages can be repeated,
with the latest result as a new initialization, to keep improving the
classification quality. We show that the convex model of the smoothing stage
has a unique solution and can be solved by a specifically designed primal-dual
algorithm whose convergence is guaranteed. We test our method and compare it
with the state-of-the-art methods on several benchmark data sets. The
experimental results demonstrate clearly that our method is superior in both
the classification accuracy and computation speed for high-dimensional data and
point clouds.Comment: 21 pages, 4 figure
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