51,615 research outputs found

    Image-guided therapy using maghemite-MOF nanovectors

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    Advances in nanotechnology offer the possibility of tailored delivery of therapeutics with real-time imaging of disease. In this issue of Chem, Steunou and co-workers amalgamate the powerful MRI properties of ultra-small paramagnetic iron oxides with the excellent drug-delivery capabilities of metal-organic frameworks to produce theranostic nanoparticulate devices for cancer treatment and imaging

    Patterns of CT lung injury and toxicity after stereotactic radiotherapy delivered with helical tomotherapy in early stage medically inoperable NSCLC

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    To evaluate toxicity and patterns of radiologic lung injury on CT images after hypofractionated image-guided stereotactic body radiotherapy (SBRT) delivered with helical tomotherapy (HT) in medically early stage inoperable non-small-cell lung cancer (NSCLC)

    Improving elevation perception with a tool for image-guided head-related transfer function selection

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    This paper proposes an image-guided HRTF selection procedure that exploits the relation between features of the pinna shape and HRTF notches. Using a 2D image of a subject's pinna, the procedure selects from a database the HRTF set that best fits the anthropometry of that subject. The proposed procedure is designed to be quickly applied and easy to use for a user without previous knowledge on binaural audio technologies. The entire process is evaluated by means of an auditory model for sound localization in the mid-sagittal plane available from previous literature. Using virtual subjects from a HRTF database, a virtual experiment is implemented to assess the vertical localization performance of the database subjects when they are provided with HRTF sets selected by the proposed procedure. Results report a statistically significant improvement in predictions of localization performance for selected HRTFs compared to KEMAR HRTF which is a commercial standard in many binaural audio solutions; moreover, the proposed analysis provides useful indications to refine the perceptually-motivated metrics that guides the selection
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