8,477 research outputs found
Patch-based Convolutional Neural Network for Whole Slide Tissue Image Classification
Convolutional Neural Networks (CNN) are state-of-the-art models for many
image classification tasks. However, to recognize cancer subtypes
automatically, training a CNN on gigapixel resolution Whole Slide Tissue Images
(WSI) is currently computationally impossible. The differentiation of cancer
subtypes is based on cellular-level visual features observed on image patch
scale. Therefore, we argue that in this situation, training a patch-level
classifier on image patches will perform better than or similar to an
image-level classifier. The challenge becomes how to intelligently combine
patch-level classification results and model the fact that not all patches will
be discriminative. We propose to train a decision fusion model to aggregate
patch-level predictions given by patch-level CNNs, which to the best of our
knowledge has not been shown before. Furthermore, we formulate a novel
Expectation-Maximization (EM) based method that automatically locates
discriminative patches robustly by utilizing the spatial relationships of
patches. We apply our method to the classification of glioma and non-small-cell
lung carcinoma cases into subtypes. The classification accuracy of our method
is similar to the inter-observer agreement between pathologists. Although it is
impossible to train CNNs on WSIs, we experimentally demonstrate using a
comparable non-cancer dataset of smaller images that a patch-based CNN can
outperform an image-based CNN
Learning a Dilated Residual Network for SAR Image Despeckling
In this paper, to break the limit of the traditional linear models for
synthetic aperture radar (SAR) image despeckling, we propose a novel deep
learning approach by learning a non-linear end-to-end mapping between the noisy
and clean SAR images with a dilated residual network (SAR-DRN). SAR-DRN is
based on dilated convolutions, which can both enlarge the receptive field and
maintain the filter size and layer depth with a lightweight structure. In
addition, skip connections and residual learning strategy are added to the
despeckling model to maintain the image details and reduce the vanishing
gradient problem. Compared with the traditional despeckling methods, the
proposed method shows superior performance over the state-of-the-art methods on
both quantitative and visual assessments, especially for strong speckle noise.Comment: 18 pages, 13 figures, 7 table
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