Influence de la température et de l'acidité sur le développement en culture de Thielaviopsis paradoxa, parasite de l'ananas

Le développement, en culture, de Thielaviopsis paradoxa, est très rapide de 25¼C à 32¼C, mais il est nettement ralenti à 12¼C. En milieu tamponné, le champignon pousse bien de pH 3 à pH 6. A pH 2,3 et 7,0, il est légèrement inhib

Creation and study of formulations as inhibitors of metal corrosion and scaling for stabilization water treatment in water utilization systems (a review)

This review summarizes studies for the past 5 years aimed at creation of efficient organophosphonate reagents for the stabilization water treatment aimed at preventing metal corrosion and scaling in water utilization systems.This study was carried out with state financial support provided by the Russian Ministry of Education and Science under Subsidy Grant Agreement No. 14.576.21.0017 of August 23, 2014

Point: From animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system.

The Apc(Min/+) mouse model and the azoxymethane (AOM) rat model are the main animal models used to study the effect of dietary agents on colorectal cancer. We reviewed recently the potency of chemopreventive agents in the AOM rat model (D. E. Corpet and S. Tache, Nutr. Cancer, 43: 1-21, 2002). Here we add the results of a systematic review of the effect of dietary and chemopreventive agents on the tumor yield in Min mice. The review is based on the results of 179 studies from 71 articles and is displayed also on the internet http://corpet.net/min.(2) We compared the efficacy of agents in the Min mouse model and the AOM rat model, and found that they were correlated (r = 0.66; P < 0.001), although some agents that afford strong protection in the AOM rat and the Min mouse small bowel increase the tumor yield in the large bowel of mutant mice. The agents included piroxicam, sulindac, celecoxib, difluoromethylornithine, and polyethylene glycol. The reason for this discrepancy is not known. We also compare the results of rodent studies with those of clinical intervention studies of polyp recurrence. We found that the effect of most of the agents tested was consistent across the animal and clinical models. Our point is thus: rodent models can provide guidance in the selection of prevention approaches to human colon cancer, in particular they suggest that polyethylene glycol, hesperidin, protease inhibitor, sphingomyelin, physical exercise, epidermal growth factor receptor kinase inhibitor, (+)-catechin, resveratrol, fish oil, curcumin, caffeate, and thiosulfonate are likely important preventive agents

Developmental changes in the association between approximate number representations and addition skills in elementary school children

The approximate number system (ANS) is assumingly related to mathematical learning but evidence supporting this assumption is mixed. The inconsistent findings might be attributed to the fact that different measures have been used to assess the ANS and mathematical skills. Moreover, associations between the performance on a measure of the ANS and mathematical skills may be discontinuous, i.e., stronger for children with lower math scores than for children with higher math scores, and may change with age. The aim of the present study was to examine the development of the ANS and arithmetic skills in elementary school children and to investigate how the relationship between the ANS and arithmetic skills develops. Individual markers of children's ANS (internal Weber fractions and mean reaction times in a non-symbolic numerical comparison task) and addition skills were assessed in their first year of school and 1 year later. Children showed improvements in addition performance and in the internal Weber fractions, whereas mean reaction times in the non-symbolic numerical comparison task did not change significantly. While children's addition performance was associated with the internal Weber fractions in the first year, it was associated with mean reaction times in the non-symbolic numerical comparison task in the second year. These associations were not found to be discontinuous and could not be explained by individual differences in reasoning, processing speed, or inhibitory control. The present study extends previous findings by demonstrating that addition performance is associated with different markers of the ANS in the course of development

METHOD FOR MODULATING EICOSANOID MEDIATED IMMUNE RESPONSES IN ARTHROPODS

The invention is directed to compositions which alter the health of invertebrate organisms by affecting eicosanoid mediated immune responses, and methods of using the compositions. The invention provides pharmaceutical com positions and biopesticide compositions. The pharmaceuti cal composition is composed of an effective amount of at least one biologically active agent which enhances or inhib its eicosanoid-mediated immune responses in invertebrate Species and a physiological compatible carrier. The biope Sticide composition is composed of a biopesticidal amount of an inhibitor of eicosanoid-mediated immune responses in invertebrates and a physiologically acceptable carrier. The pharmaceutical compositions are useful to treat invertebrate Species to enhance or inhibit immune responses. The bio pesticide composition is useful to control the growth of or eradicate invertebrate pests. Methods are provided for deter mining which and what amounts of the biologically active agents are useful in the composition

Nonsteroidal Anti-Inflammatory Agents in the Therapy for Experimental Pneumococcal Meningitis

An increased inflammatory mass in the subarachnoid space during bacterial meningitis may correlate with a poor outcome of disease. Using a rabbit model of pneumococcal meningitis, we sought to reduce this inflammatory process. The ability of the pneumococcal cell wall to cause death and to generate leukocytosis and abnormal chemistry in cerebrospinal fluid was prevented when animals were treated with inhibitors of the cyclooxygenase pathway of arachidonate metabolism. Bacterial lysis by ampicillin led to release of cell wall that caused a significant, transient increase in meningeal inflammation. This inflammatory burst was also prevented by administering cyclooxygenase inhib-itors concurrently with the antibioti

A Forward Reachability Algorithm for Bounded Timed-Arc Petri Nets

Timed-arc Petri nets (TAPN) are a well-known time extension of the Petri net model and several translations to networks of timed automata have been proposed for this model. We present a direct, DBM-based algorithm for forward reachability analysis of bounded TAPNs extended with transport arcs, inhibitor arcs and age invariants. We also give a complete proof of its correctness, including reduction techniques based on symmetries and extrapolation. Finally, we augment the algorithm with a novel state-space reduction technique introducing a monotonic ordering on markings and prove its soundness even in the presence of monotonicity-breaking features like age invariants and inhibitor arcs. We implement the algorithm within the model-checker TAPAAL and the experimental results document an encouraging performance compared to verification approaches that translate TAPN models to UPPAAL timed automata.Comment: In Proceedings SSV 2012, arXiv:1211.587