207,016 research outputs found
Entry in the ADHD drugs market: Welfare impact of generics and me-toos
Recent decades have seen a growth in treatments for attention deficit hyperactivity disorder (ADHD) including many branded and generic drugs. In the early 2000's, new drug entry dramatically altered market shares. We estimate a demand system for ADHD drugs and assess the welfare impact of new drugs. We find that entry induced large welfare gains by reducing prices of substitute drugs, and by providing alternative delivery mechanisms for existing molecules. Our results suggest that the success of follow-on patented drugs may come from unanticipated innovations like delivery mechanisms, a factor ignored by proposals to retard new follow-on drug approvals
The Cowl - v.33 - n.7 - Oct 8, 1980
The Cowl - student newspaper of Providence College. Vol 33 - No. 7 - October 8, 1980. 12 pages
Epidemiology and immunogenetic background of islet cell antibody - positive nondiabetic schoolchildren : Ulm-Frankfurt population study
Islet cell antibodies (ICAs) were determined in a large cohort of white nondiabetic schoolchildren (n = 4287) from a homogenous population in southern Germany. The prevalence of ICA levels greater than or equal to 5 Juvenile Diabetes Foundation (JDF) U was 1.05% (95% confidence interval 0.8-1.4%). Analysis of HLA-DR beta and -DQ beta alleles revealed that the specificities found to be increased in insulin-dependent (type I) diabetic subjects with the same ethnic background were also associated with ICA positivity in the nondiabetic schoolchildren. HLA-DR3 (P less than 0.01) and -DR4 (P less than 0.01) phenotypes and absence of Asp residue (P less than 0.01) at codon 57 of the HLA-DQ beta-chain were significantly increased in ICA+ compared with control subjects. High levels of ICAs, which were categorized as either greater than or equal to 17 or greater than or equal to 30 JDF U, were found to be associated with amino acids other than Asp at position 57 of the HLA-DQ beta-chain. No association of ICA level was found for HLA-DR phenotypes
The Cowl - v.30 - n.8 - Mar 30, 1977
The Cowl - student newspaper of Providence College. Volume 30, Number 8 - March 30, 1977. 12 pages. Note: The volume number printed on the banner page of this issue (XXX) duplicates the volume number for the 1967-68 academic year
The Cowl - v.33 - n.18 - Mar 11, 1981
The Cowl - student newspaper of Providence College. Volume 33 - March 11, 1981. 12 pages
The Cowl - v.33 - n.13 - Jan 22, 1981
The Cowl - student newspaper of Providence College. Volume 33 - January 22, 1981. 12 pages
The Cowl - v.10 - n.1 - Oct 1, 1947
The Cowl - student newspaper of Providence College. Volume 10, Number 1 - Oct 1, 1947. 4 pages
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