Robust Estimation of Hypernasality in Dysarthria with Acoustic Model Likelihood Features

Hypernasality is a common characteristic symptom across many motor-speech disorders. For voiced sounds, hypernasality introduces an additional resonance in the lower frequencies and, for unvoiced sounds, there is reduced articulatory precision due to air escaping through the nasal cavity. However, the acoustic manifestation of these symptoms is highly variable, making hypernasality estimation very challenging, both for human specialists and automated systems. Previous work in this area relies on either engineered features based on statistical signal processing or machine learning models trained on clinical ratings. Engineered features often fail to capture the complex acoustic patterns associated with hypernasality, whereas metrics based on machine learning are prone to overfitting to the small disease-specific speech datasets on which they are trained. Here we propose a new set of acoustic features that capture these complementary dimensions. The features are based on two acoustic models trained on a large corpus of healthy speech. The first acoustic model aims to measure nasal resonance from voiced sounds, whereas the second acoustic model aims to measure articulatory imprecision from unvoiced sounds. To demonstrate that the features derived from these acoustic models are specific to hypernasal speech, we evaluate them across different dysarthria corpora. Our results show that the features generalize even when training on hypernasal speech from one disease and evaluating on hypernasal speech from another disease (e.g. training on Parkinson's disease, evaluation on Huntington's disease), and when training on neurologically disordered speech but evaluating on cleft palate speech.Comment: 12 pages, 9 figures, 2 table

A Deep Learning Algorithm for Objective Assessment of Hypernasality in Children with Cleft Palate

Objectives: Evaluation of hypernasality requires extensive perceptual training by clinicians and extending this training on a large scale internationally is untenable; this compounds the health disparities that already exist among children with cleft. In this work, we present the objective hypernasality measure (OHM), a speech analytics algorithm that automatically measures hypernasality in speech, and validate it relative to a group of trained clinicians. Methods: We trained a deep neural network (DNN) on approximately 100 hours of a publicly-available healthy speech corpus to detect the presence of nasal acoustic cues generated through the production of nasal consonants and nasalized phonemes in speech. Importantly, this model does not require any clinical data for training. The posterior probabilities of the deep learning model were aggregated at the sentence and speaker-levels to compute the OHM. Results: The results showed that the OHM was significantly correlated with the perceptual hypernasality ratings in the Americleft database ( r=0.797, ~p$<$0.001), and with the New Mexico Cleft Palate Center (NMCPC) database (r=0.713,p<$0.001). In addition, we evaluated the relationship between the OHM and articulation errors; the sensitivity of the OHM in detecting the presence of very mild hypernasality; and establishing the internal reliability of the metric. Further, the performance of OHM was compared with a DNN regression algorithm directly trained on the hypernasal speech samples. Significance: The results indicate that the OHM is able to rate the severity of hypernasality on par with Americleft-trained clinicians on this dataset