751 research outputs found
Multi-Planar Deep Segmentation Networks for Cardiac Substructures from MRI and CT
Non-invasive detection of cardiovascular disorders from radiology scans
requires quantitative image analysis of the heart and its substructures. There
are well-established measurements that radiologists use for diseases assessment
such as ejection fraction, volume of four chambers, and myocardium mass. These
measurements are derived as outcomes of precise segmentation of the heart and
its substructures. The aim of this paper is to provide such measurements
through an accurate image segmentation algorithm that automatically delineates
seven substructures of the heart from MRI and/or CT scans. Our proposed method
is based on multi-planar deep convolutional neural networks (CNN) with an
adaptive fusion strategy where we automatically utilize complementary
information from different planes of the 3D scans for improved delineations.
For CT and MRI, we have separately designed three CNNs (the same architectural
configuration) for three planes, and have trained the networks from scratch for
voxel-wise labeling for the following cardiac structures: myocardium of left
ventricle (Myo), left atrium (LA), left ventricle (LV), right atrium (RA),
right ventricle (RV), ascending aorta (Ao), and main pulmonary artery (PA). We
have evaluated the proposed method with 4-fold-cross validation on the
multi-modality whole heart segmentation challenge (MM-WHS 2017) dataset. The
precision and dice index of 0.93 and 0.90, and 0.87 and 0.85 were achieved for
CT and MR images, respectively. While a CT volume was segmented about 50
seconds, an MRI scan was segmented around 17 seconds with the GPUs/CUDA
implementation.Comment: The paper is accepted to STACOM 201
Iterative Segmentation from Limited Training Data: Applications to Congenital Heart Disease
We propose a new iterative segmentation model which can be accurately learned
from a small dataset. A common approach is to train a model to directly segment
an image, requiring a large collection of manually annotated images to capture
the anatomical variability in a cohort. In contrast, we develop a segmentation
model that recursively evolves a segmentation in several steps, and implement
it as a recurrent neural network. We learn model parameters by optimizing the
interme- diate steps of the evolution in addition to the final segmentation. To
this end, we train our segmentation propagation model by presenting incom-
plete and/or inaccurate input segmentations paired with a recommended next
step. Our work aims to alleviate challenges in segmenting heart structures from
cardiac MRI for patients with congenital heart disease (CHD), which encompasses
a range of morphological deformations and topological changes. We demonstrate
the advantages of this approach on a dataset of 20 images from CHD patients,
learning a model that accurately segments individual heart chambers and great
vessels. Com- pared to direct segmentation, the iterative method yields more
accurate segmentation for patients with the most severe CHD malformations.Comment: Presented at the Deep Learning in Medical Image Analysis Workshop,
MICCAI 201
Adversarial Convolutional Networks with Weak Domain-Transfer for Multi-sequence Cardiac MR Images Segmentation
Analysis and modeling of the ventricles and myocardium are important in the
diagnostic and treatment of heart diseases. Manual delineation of those tissues
in cardiac MR (CMR) scans is laborious and time-consuming. The ambiguity of the
boundaries makes the segmentation task rather challenging. Furthermore, the
annotations on some modalities such as Late Gadolinium Enhancement (LGE) MRI,
are often not available. We propose an end-to-end segmentation framework based
on convolutional neural network (CNN) and adversarial learning. A dilated
residual U-shape network is used as a segmentor to generate the prediction
mask; meanwhile, a CNN is utilized as a discriminator model to judge the
segmentation quality. To leverage the available annotations across modalities
per patient, a new loss function named weak domain-transfer loss is introduced
to the pipeline. The proposed model is evaluated on the public dataset released
by the challenge organizer in MICCAI 2019, which consists of 45 sets of
multi-sequence CMR images. We demonstrate that the proposed adversarial
pipeline outperforms baseline deep-learning methods.Comment: 9 pages, 4 figures, conferenc
Deep Learning in Cardiology
The medical field is creating large amount of data that physicians are unable
to decipher and use efficiently. Moreover, rule-based expert systems are
inefficient in solving complicated medical tasks or for creating insights using
big data. Deep learning has emerged as a more accurate and effective technology
in a wide range of medical problems such as diagnosis, prediction and
intervention. Deep learning is a representation learning method that consists
of layers that transform the data non-linearly, thus, revealing hierarchical
relationships and structures. In this review we survey deep learning
application papers that use structured data, signal and imaging modalities from
cardiology. We discuss the advantages and limitations of applying deep learning
in cardiology that also apply in medicine in general, while proposing certain
directions as the most viable for clinical use.Comment: 27 pages, 2 figures, 10 table
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