Bostonia: The Boston University Alumni Magazine. Volume 9

Founded in 1900, Bostonia magazine is Boston University's main alumni publication, which covers alumni and student life, as well as university activities, events, and programs

Ultrasound-mediated transdermal drug delivery: Mechanisms, scope, and emerging trends

The use of ultrasound for the delivery of drugs to, or through, the skin is commonly known as sonophoresis or phonophoresis. The use of therapeutic and high frequencies of ultrasound (≥ 0.7 MHz) for sonophoresis (HFS) dates back to as early as the 1950s, while low-frequency sonophoresis (LFS, 20–100 kHz) has only been investigated significantly during the past two decades. Although HFS and LFS are similar because they both utilize ultrasound to increase the skin penetration of permeants, the mechanisms associated with each physical enhancer are different. Specifically, the location of cavitation and the extent to which each process can increase skin permeability are quite dissimilar. Although the applications of both technologies are different, they each have strengths that could allow them to improve current methods of local, regional, and systemic drug delivery. In this review, we will discuss the mechanisms associated with both HFS and LFS, specifically concentrating on the key mechanistic differences between these two skin treatment methods. Background on the relevant physics associated with ultrasound transmitted through aqueous media will also be discussed, along with implications of these phenomena on sonophoresis. Finally, a thorough review of the literature is included, dating back to the first published reports of sonophoresis, including a discussion of emerging trends in the field.National Institutes of Health (U.S.) (Grant EB-00351)Massachusetts Institute of Technology. Institute for Soldier Nanotechnologies (Grant DAAD-19-02-D-002

'At the Mercy of the German Eagle': images of London in dissolution in the novels of William Le Queux

The works of the prolific author, William Le Queux, represent the highpoint of the German 'invasion panic' genre in the years before 1914. Widely read by contemporaries, his novels provided a catalyst for British debates about the economic, military and spiritual exhaustion of the empire in the face of new national and imperial rivals. For Le Queux, the capture of London was integral to German military occupation. Either buttressing the capital’s will to resist, or undermining its capacity to withstand attack, the vigour and vitality of London was always at issue in his novels. Drawing on contemporary fears about the capital and its dissolution, this article considers the moral panics about London and Londoners and their relationship to Britain’s martial decline reflected in his stories. Ranging across anxieties about anarchist and foreign terrorism, attuned to fears of the mob, and suspicious about wealthy spy masters at large in governmental circles, Le Queux’s fiction reflects concerns about London as a decadent ’new Rome’ in process of lengthy and agonising disintegration. Le Queux pursued a populist path in his vision of an embattled London, brought low by a decadent leadership but saved by a population purged of bankers, outsiders, immigrants, its cultural establishment, and defeatists. Analysing these themes in Le Queux’s fiction, this article exposes the vein of anxiety about the defence of London in the invasion panic genre, and raises questions about the degree to which contemporaries believed the nation might turn to the capital for its salvation in its hour of need

‘John Hewitt: Creating a Canon of Ulster Art’

This article explores the role of John Hewitt (1907 – 87) in attempting to articulate a distinctive artistic and cultural identity for Ulster from the middle of the twentieth century. Focusing on Hewitt’s interpretation of the visual arts, this essay examines the ways in which he acted as a curator and advocate for particular artists who he felt embodied his sense of a regional style of art for Ulster. Hewitt’s work is contextualised by a broader discussion of ideas of national and regional identity following the Second World War, and also by the increasingly visible avant-garde centres of artistic development in places such as London and New York

Bioarchaeological Investigations of Nineteenth-Century African American Burials at the Pioneer Cemetery (41BO202) in Brazoria, Texas

A search for unmarked graves in the state-owned right of way and underneath the pavement of State Highway 332 resulted in the discovery and archeological excavation of 11 unmarked graves associated with Pioneer Cemetery, an African American burial ground in Brazoria, Texas. Prewitt and Associates, Inc., conducted the fieldwork for the Texas Department of Transportation’s Archeological Studies Program. Between 2008 and 2012, the 11 unmarked graves were discovered, exhumed, analyzed, and then reinterred in Pioneer Cemetery in September 2012. This report describes the bioarcheological investigations of those burials along with 3 other unmarked burials that were previously exhumed and reburied in 2003. The mortuary remains, especially the manufacturing dates on the coffin hardware, indicate that the 14 exhumed burials date to the late-nineteenth century and early-twentieth centuries. Based on the osteological evidence, the deceased persons were 5 women, 2 men, 2 indeterminate adults, and 5 children. Seven of the 14 individuals display skeletal traits indicating that they are of African descent, but 2 indeterminate adults and 5 children do not. Based on historical evidence, it is likely that all 14 individuals were African Americans, and several of the older individuals may have been born into slavery. These 14 burials do not constitute a representative sample of the African Americans in Brazoria County or the town of Brazoria, but they are an interesting and historically significant burial population nonetheless. The overall health status of these people was generally good, with no evidence of abnormally high pathologies. However, skeletal remains of several older individuals exhibited evidence of various forms of degenerative joint disease indicative of lives spent doing hard labor. One adult male had an amputated leg and an iron and wooden prosthesis; it is not known if the loss of his leg was due to violence, accidental trauma, or disease. Several of the Pioneer burials exhibit traits that may represent mortuary behaviors of African origin. Three individuals had vaulted burials, with the casket or coffin located inside a shaft under a protective wooden arch. One adult female was buried with a complete whiteware saucer and a bird talon that was partially wrapped in gold plating and may have been worn as a necklace

Howard Gest Special Collection: Associations with outstanding scientists during a research career in microbiology and biochemistry

Associations with distinguished scientists during an academic career of over 60 years. Memorabilia include various research papers, books, correspondence, photographs and obituaries

The Lows of Lowes Cove (1830s-1880s)

This is about the people and place of Wentworth Point in Walpole, Maine before the inception of the Darling Marine Center in 1965. This is about the Lowe family, and the Bennett family, and the Haggett family during the 19th century. It is about Lowe\u27s Cove and the neighbors of the Lowe family

The Norwegian Ancestry of Oscar Martin Remington; Tracing his Roots in Roldal Parish, Hordaland County and Suldal Parish, Rogaland County, Norway and Telling the Story of his Family in Juneau County, Wisconsin

Cataloging Data Onsager, Lawrence William, 1944- The Norwegian Ancestry of Oscar Martin Remington; Tracing His Roots in Roldal Parish, Hordaland County and Suldal Parish, Rogaland County, Norway and Telling the Story of His Family in Juneau County, Wisconsin. Mauston, Wisconsin and Berrien Springs, Michigan: The Lemonweir Valley Press, 2018. 1. Juneau County, Wisconsin 2. Norwegian-Americans--Wisconsin 3. Clifton Township, Monroe County, Wisconsin 4. Suldal Norwegian-American Settlement 5. Suldal Parish, Rogaland County, Norway 6. Roldal Parish, Hordaland County, Norway 7. Knutson Family 8. Remington Famil

Supplying new cocoa planting material to farmers: a review of propagation methodologies

The review, coordinated by Bioversity International, presents an impartial, evidence-based review of cacao propagation methods, to serve as a basis for the assessment and implementation of strategies for providing farmers with quality planting materials, adapted to current and future needs (cultural, institutional, technical, environmental and financial). It describes the various propagation methods available for the production and supply of large numbers of cacao plants to growers. It is hoped that the result of the efforts of the key authors provides a basis to build on for case-specific recommendations. As the supply of new improved planting material to farmers is at the heart of improving cocoa productivity and modernizing the crop, we hope that the information in the review will make its way into national cocoa plans, and help to make cocoa farming more attractive and more sustainable